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[Efficacy comparison between electroacupuncture and dyne-35 in treatment of polycystic ovary syndrome].
Zhongguo Zhen Jiu. 2014 Dec; 34(12):1174-8.ZZ

Abstract

OBJECTIVE

To compare the difference in clinical efficacy on polycystic ovary syndrome (PCOS) between electroacupuncture (EA) and dyne-35 and to explore the effect mechanism.

METHODS

Sixty-five patients were randomized into an EA group (33 cases) and a western medication group (32 cases). In the EA group, the selected acupoints were Danzhong (CV 17), Qimen (LR 14), Zhongwan (CV 12), Tianshu (ST 25), Guanyuan (CV 4), Zigong (EX-CA 1), Sanyinjiao (SP 6), Zusanli (ST 36) and Taichong (LR 3), etc. After the arrival of qi, electric stimulation was attached to the acupoints for 30 min. The treatment was given 3 times a week. In the western medication group, dyne-35 was prescribed on the 5th day of natural menstruation or withdrawal bleeding, one tablet a day, continuously for 21 days. The treatment cycle was 3 months in the two groups. The menstrual condition, body mass, body mass index (BMI), serum testosterone (T), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and LH/FSH were compared before and after treatment in the two groups. The clinical efficacy was assessed in the two groups.

RESULTS

The total effective rate was 90.6% (29/32) in the EA group and was 93.3% (28/30) in the western medication group. The efficacy was similar in the two groups (P > 0.05). After treatment, the levels of LH and LH/FSH were all reduced significantly in the two groups (all P < 0.01). After treatment, T level in serum was reduced apparently in the western medication group (P < 0.05). Before and after treatment, the differences in body mass and BMI in the EA group were more significant than those in the western medication group (P < 0.01, P < 0.05).

CONCLUSION

EA is the effective method for PCOS, similar to that of dyne-35. The effect of it for weight loss is superior to dyne-35 and no apparent adverse reactions happen. The effect mechanism of EA is related to the regulation of serum sexual hormone levels and their ratio, as well as to the regulation of body lipid metabolism.

Authors

Jin CL
No affiliation info available
Wei LX
No affiliation info available
Zhao JP
No affiliation info available
Wu ZC
No affiliation info available

MeSH

Acupuncture PointsAdolescentAdultCyproterone AcetateDrug CombinationsElectroacupunctureEthinyl EstradiolFemaleFollicle Stimulating HormoneHumansLuteinizing HormonePolycystic Ovary SyndromeYoung Adult

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

25876344

Citation

Jin, Chun-Lan, et al. "[Efficacy Comparison Between Electroacupuncture and Dyne-35 in Treatment of Polycystic Ovary Syndrome]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 34, no. 12, 2014, pp. 1174-8.
Jin CL, Wei LX, Zhao JP, et al. [Efficacy comparison between electroacupuncture and dyne-35 in treatment of polycystic ovary syndrome]. Zhongguo Zhen Jiu. 2014;34(12):1174-8.
Jin, C. L., Wei, L. X., Zhao, J. P., & Wu, Z. C. (2014). [Efficacy comparison between electroacupuncture and dyne-35 in treatment of polycystic ovary syndrome]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 34(12), 1174-8.
Jin CL, et al. [Efficacy Comparison Between Electroacupuncture and Dyne-35 in Treatment of Polycystic Ovary Syndrome]. Zhongguo Zhen Jiu. 2014;34(12):1174-8. PubMed PMID: 25876344.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Efficacy comparison between electroacupuncture and dyne-35 in treatment of polycystic ovary syndrome]. AU - Jin,Chun-Lan, AU - Wei,Li-Xin, AU - Zhao,Ji-Ping, AU - Wu,Zhong-Chao, PY - 2015/4/17/entrez PY - 2015/4/17/pubmed PY - 2015/5/9/medline SP - 1174 EP - 8 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 34 IS - 12 N2 - OBJECTIVE: To compare the difference in clinical efficacy on polycystic ovary syndrome (PCOS) between electroacupuncture (EA) and dyne-35 and to explore the effect mechanism. METHODS: Sixty-five patients were randomized into an EA group (33 cases) and a western medication group (32 cases). In the EA group, the selected acupoints were Danzhong (CV 17), Qimen (LR 14), Zhongwan (CV 12), Tianshu (ST 25), Guanyuan (CV 4), Zigong (EX-CA 1), Sanyinjiao (SP 6), Zusanli (ST 36) and Taichong (LR 3), etc. After the arrival of qi, electric stimulation was attached to the acupoints for 30 min. The treatment was given 3 times a week. In the western medication group, dyne-35 was prescribed on the 5th day of natural menstruation or withdrawal bleeding, one tablet a day, continuously for 21 days. The treatment cycle was 3 months in the two groups. The menstrual condition, body mass, body mass index (BMI), serum testosterone (T), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and LH/FSH were compared before and after treatment in the two groups. The clinical efficacy was assessed in the two groups. RESULTS: The total effective rate was 90.6% (29/32) in the EA group and was 93.3% (28/30) in the western medication group. The efficacy was similar in the two groups (P > 0.05). After treatment, the levels of LH and LH/FSH were all reduced significantly in the two groups (all P < 0.01). After treatment, T level in serum was reduced apparently in the western medication group (P < 0.05). Before and after treatment, the differences in body mass and BMI in the EA group were more significant than those in the western medication group (P < 0.01, P < 0.05). CONCLUSION: EA is the effective method for PCOS, similar to that of dyne-35. The effect of it for weight loss is superior to dyne-35 and no apparent adverse reactions happen. The effect mechanism of EA is related to the regulation of serum sexual hormone levels and their ratio, as well as to the regulation of body lipid metabolism. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/25876344/[Efficacy_comparison_between_electroacupuncture_and_dyne_35_in_treatment_of_polycystic_ovary_syndrome]_ DB - PRIME DP - Unbound Medicine ER -