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Seroprevalence of HIV, HBV, HCV, and HTLV among Pregnant Women in Southwestern Nigeria.
J Immunoassay Immunochem. 2016; 37(1):29-42.JI

Abstract

Sexually transmitted infections (STIs) are major public health challenge especially in developing countries. This study was designed to determine the prevalence of Hepatitis B virus (HBV), Hepatitis C Virus (HCV), Human immunodeficiency virus (HIV), and Human T-cell lymphotropic Virus type I (HTLV-I) among pregnant women attending antenatal clinic, in Ladoke Akintola University Teaching Hospital, Osogbo, and South-Western Nigeria. One hundred and eighty two randomly selected pregnant women were screened for HBsAg, anti-HCV, anti-HIV and HTLV-1 IgM antibodies using commercially available ELISA kit. Of the 182 blood samples of pregnant women screened whose age ranged from 15-49 years, 13 (7.1%), 5 (2.7%), 9 (4.9%), and 44 (24.2%) were positive for HBsAg, anti-HCV, anti-HIV, and HTLV-1 IgM antibodies, respectively. The co-infection rate of 0.5% was obtained for HBV/HCV, HBV/HIV, HIV/HTLV-1, and HCV/HTLV-1 while 1.1% and 0% was recorded for HBV/HTLV-1 and HCV/HIV co-infections, respectively. Expected risk factors such as history of surgery, circumcision, tattooing and incision showed no significant association with any of the viral STIs (P > 0.05). This study shows that there is the need for a comprehensive screening of all pregnant women for HBsAg, anti-HCV, anti-HIV and HTLV-1 to prevent mother to child transmission of these viral infections and its attending consequences.

Authors+Show Affiliations

a Department of Medical Microbiology and Parasitology , College of Health Sciences, Ladoke Akintola University of Technology , Osogbo , Nigeria.a Department of Medical Microbiology and Parasitology , College of Health Sciences, Ladoke Akintola University of Technology , Osogbo , Nigeria.a Department of Medical Microbiology and Parasitology , College of Health Sciences, Ladoke Akintola University of Technology , Osogbo , Nigeria.a Department of Medical Microbiology and Parasitology , College of Health Sciences, Ladoke Akintola University of Technology , Osogbo , Nigeria.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

25879258

Citation

Opaleye, Oluyinka Oladele, et al. "Seroprevalence of HIV, HBV, HCV, and HTLV Among Pregnant Women in Southwestern Nigeria." Journal of Immunoassay & Immunochemistry, vol. 37, no. 1, 2016, pp. 29-42.
Opaleye OO, Igboama MC, Ojo JA, et al. Seroprevalence of HIV, HBV, HCV, and HTLV among Pregnant Women in Southwestern Nigeria. J Immunoassay Immunochem. 2016;37(1):29-42.
Opaleye, O. O., Igboama, M. C., Ojo, J. A., & Odewale, G. (2016). Seroprevalence of HIV, HBV, HCV, and HTLV among Pregnant Women in Southwestern Nigeria. Journal of Immunoassay & Immunochemistry, 37(1), 29-42. https://doi.org/10.1080/15321819.2015.1040160
Opaleye OO, et al. Seroprevalence of HIV, HBV, HCV, and HTLV Among Pregnant Women in Southwestern Nigeria. J Immunoassay Immunochem. 2016;37(1):29-42. PubMed PMID: 25879258.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seroprevalence of HIV, HBV, HCV, and HTLV among Pregnant Women in Southwestern Nigeria. AU - Opaleye,Oluyinka Oladele, AU - Igboama,Magdalene C, AU - Ojo,Johnson Adeyemi, AU - Odewale,Gbolabo, PY - 2015/4/17/entrez PY - 2015/4/17/pubmed PY - 2016/10/8/medline KW - HBV KW - HCV KW - HIV KW - HTLV-1 KW - co-infection KW - seroprevalence KW - sexually transmitted infections SP - 29 EP - 42 JF - Journal of immunoassay & immunochemistry JO - J Immunoassay Immunochem VL - 37 IS - 1 N2 - Sexually transmitted infections (STIs) are major public health challenge especially in developing countries. This study was designed to determine the prevalence of Hepatitis B virus (HBV), Hepatitis C Virus (HCV), Human immunodeficiency virus (HIV), and Human T-cell lymphotropic Virus type I (HTLV-I) among pregnant women attending antenatal clinic, in Ladoke Akintola University Teaching Hospital, Osogbo, and South-Western Nigeria. One hundred and eighty two randomly selected pregnant women were screened for HBsAg, anti-HCV, anti-HIV and HTLV-1 IgM antibodies using commercially available ELISA kit. Of the 182 blood samples of pregnant women screened whose age ranged from 15-49 years, 13 (7.1%), 5 (2.7%), 9 (4.9%), and 44 (24.2%) were positive for HBsAg, anti-HCV, anti-HIV, and HTLV-1 IgM antibodies, respectively. The co-infection rate of 0.5% was obtained for HBV/HCV, HBV/HIV, HIV/HTLV-1, and HCV/HTLV-1 while 1.1% and 0% was recorded for HBV/HTLV-1 and HCV/HIV co-infections, respectively. Expected risk factors such as history of surgery, circumcision, tattooing and incision showed no significant association with any of the viral STIs (P > 0.05). This study shows that there is the need for a comprehensive screening of all pregnant women for HBsAg, anti-HCV, anti-HIV and HTLV-1 to prevent mother to child transmission of these viral infections and its attending consequences. SN - 1532-4230 UR - https://www.unboundmedicine.com/medline/citation/25879258/Seroprevalence_of_HIV_HBV_HCV_and_HTLV_among_Pregnant_Women_in_Southwestern_Nigeria_ L2 - https://www.tandfonline.com/doi/full/10.1080/15321819.2015.1040160 DB - PRIME DP - Unbound Medicine ER -