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Childhood trauma and childhood urbanicity in relation to psychotic disorder.
Soc Psychiatry Psychiatr Epidemiol. 2015 Oct; 50(10):1481-8.SP

Abstract

BACKGROUND

Urban upbringing and childhood trauma are both associated with psychotic disorders. However, the association between childhood urbanicity and childhood trauma in psychosis is poorly understood. The urban environment could occasion a background of social adversity against which any effect of childhood trauma increases. Also, any impact of the urban environment on likelihood of exposure to childhood trauma could be stronger in children who later develop psychotic disorder. The aim of this study was twofold: (1) to investigate whether childhood urbanicity moderates the effect of childhood trauma, in a model predicting psychotic disorder; (2) to investigate whether there is an association between the urban environment and childhood trauma and whether this is moderated by genetic liability for psychotic disorder.

METHODS

Patients with a diagnosis of non-affective psychotic disorder (n = 1119) and 589 healthy controls from the Netherlands and Belgium were studied. Childhood trauma was assessed with the Dutch version of the Childhood Trauma Questionnaire Short Form. Urban exposure was defined at four levels, considering the population density, using data from Statistics Netherlands and the equivalent database in Belgium.

RESULTS

There was a significant interaction between childhood urbanicity on the one hand and childhood trauma on the other, indicating that trauma was significantly associated with psychotic disorder, with increasing odds ratios for higher levels of childhood urbanicity. In addition, there was weak evidence that childhood urbanicity was associated with childhood trauma in the patient group: higher levels of childhood urbanicity were associated with higher trauma scores.

CONCLUSION

The urban environment may moderate the risk-increasing effect of childhood trauma for psychotic disorder and childhood urbanicity may be a risk factor for childhood trauma in individuals who later develop psychotic disorder.

Authors+Show Affiliations

Department of Psychiatry and Psychology, Maastricht University, PO Box 616 (DRT10), 6200 MD, Maastricht, The Netherlands.Department of Psychiatry and Psychology, Maastricht University, PO Box 616 (DRT10), 6200 MD, Maastricht, The Netherlands. R.Lieverse@maastrichtuniversity.nl.Department of Psychiatry and Psychology, Maastricht University, PO Box 616 (DRT10), 6200 MD, Maastricht, The Netherlands.Department of Psychiatry and Psychology, Maastricht University, PO Box 616 (DRT10), 6200 MD, Maastricht, The Netherlands.Department of Psychiatry and Psychology, Maastricht University, PO Box 616 (DRT10), 6200 MD, Maastricht, The Netherlands.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

25895686

Citation

Frissen, Aleida, et al. "Childhood Trauma and Childhood Urbanicity in Relation to Psychotic Disorder." Social Psychiatry and Psychiatric Epidemiology, vol. 50, no. 10, 2015, pp. 1481-8.
Frissen A, Lieverse R, Drukker M, et al. Childhood trauma and childhood urbanicity in relation to psychotic disorder. Soc Psychiatry Psychiatr Epidemiol. 2015;50(10):1481-8.
Frissen, A., Lieverse, R., Drukker, M., van Winkel, R., & Delespaul, P. (2015). Childhood trauma and childhood urbanicity in relation to psychotic disorder. Social Psychiatry and Psychiatric Epidemiology, 50(10), 1481-8. https://doi.org/10.1007/s00127-015-1049-7
Frissen A, et al. Childhood Trauma and Childhood Urbanicity in Relation to Psychotic Disorder. Soc Psychiatry Psychiatr Epidemiol. 2015;50(10):1481-8. PubMed PMID: 25895686.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Childhood trauma and childhood urbanicity in relation to psychotic disorder. AU - Frissen,Aleida, AU - Lieverse,Ritsaert, AU - Drukker,Marjan, AU - van Winkel,Ruud, AU - Delespaul,Philippe, AU - ,, Y1 - 2015/04/21/ PY - 2014/07/08/received PY - 2015/03/23/accepted PY - 2015/4/22/entrez PY - 2015/4/22/pubmed PY - 2016/3/24/medline KW - Childhood KW - Environment KW - Psychosis KW - Trauma KW - Urbanicity SP - 1481 EP - 8 JF - Social psychiatry and psychiatric epidemiology JO - Soc Psychiatry Psychiatr Epidemiol VL - 50 IS - 10 N2 - BACKGROUND: Urban upbringing and childhood trauma are both associated with psychotic disorders. However, the association between childhood urbanicity and childhood trauma in psychosis is poorly understood. The urban environment could occasion a background of social adversity against which any effect of childhood trauma increases. Also, any impact of the urban environment on likelihood of exposure to childhood trauma could be stronger in children who later develop psychotic disorder. The aim of this study was twofold: (1) to investigate whether childhood urbanicity moderates the effect of childhood trauma, in a model predicting psychotic disorder; (2) to investigate whether there is an association between the urban environment and childhood trauma and whether this is moderated by genetic liability for psychotic disorder. METHODS: Patients with a diagnosis of non-affective psychotic disorder (n = 1119) and 589 healthy controls from the Netherlands and Belgium were studied. Childhood trauma was assessed with the Dutch version of the Childhood Trauma Questionnaire Short Form. Urban exposure was defined at four levels, considering the population density, using data from Statistics Netherlands and the equivalent database in Belgium. RESULTS: There was a significant interaction between childhood urbanicity on the one hand and childhood trauma on the other, indicating that trauma was significantly associated with psychotic disorder, with increasing odds ratios for higher levels of childhood urbanicity. In addition, there was weak evidence that childhood urbanicity was associated with childhood trauma in the patient group: higher levels of childhood urbanicity were associated with higher trauma scores. CONCLUSION: The urban environment may moderate the risk-increasing effect of childhood trauma for psychotic disorder and childhood urbanicity may be a risk factor for childhood trauma in individuals who later develop psychotic disorder. SN - 1433-9285 UR - https://www.unboundmedicine.com/medline/citation/25895686/Childhood_trauma_and_childhood_urbanicity_in_relation_to_psychotic_disorder_ L2 - https://dx.doi.org/10.1007/s00127-015-1049-7 DB - PRIME DP - Unbound Medicine ER -