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[Acute biphenotypic leukemia followed by two color flow cytometry].
Rinsho Ketsueki. 1989 Oct; 30(10):1810-4.RK

Abstract

In this paper is reported a case of acute biphenotypic leukemia who was treated by chemotherapy and pursued its effect by two color flow cytometry. A 33-year-old male patient was admitted due to fever and general fatigue and diagnosed as acute leukemia by hematological findings. Surface markers were investigated to find positive reaction of Leu 12 (CD19), J 5 (CD10), My 7 (CD13) and My 9 (CD33), in which Leu 12 and My 9 were simultaneously expressed on the same blast cells by two color flow cytometry. He was treated with daunorubicin, enocitabine, mercaptopurine, vincristine, and prednisolone to obtain partial remission. Then, he was administered L-asparaginase, doxorubicin, vincristine and prednisolone to reach complete remission. The effect of chemotherapy was investigated by not only bone marrow puncture, but also by two color flow cytometry. From the findings in this case, the two flow cytometry was proved to be a useful tool for not only diagnosis of acute mixed leukemia, aut also the judgement of the effect of treatment.

Authors

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Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

jpn

PubMed ID

2593247

Citation

Watanabe, M, et al. "[Acute Biphenotypic Leukemia Followed By Two Color Flow Cytometry]." [Rinsho Ketsueki] the Japanese Journal of Clinical Hematology, vol. 30, no. 10, 1989, pp. 1810-4.
Watanabe M, Shimamoto Y, Sano M, et al. [Acute biphenotypic leukemia followed by two color flow cytometry]. Rinsho Ketsueki. 1989;30(10):1810-4.
Watanabe, M., Shimamoto, Y., Sano, M., Matsuzaki, M., Suga, K., Tokioka, T., Sueoka, E., Ono, K., Yamaguchi, M., & Nagumo, F. (1989). [Acute biphenotypic leukemia followed by two color flow cytometry]. [Rinsho Ketsueki] the Japanese Journal of Clinical Hematology, 30(10), 1810-4.
Watanabe M, et al. [Acute Biphenotypic Leukemia Followed By Two Color Flow Cytometry]. Rinsho Ketsueki. 1989;30(10):1810-4. PubMed PMID: 2593247.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Acute biphenotypic leukemia followed by two color flow cytometry]. A1 - Watanabe,M, AU - Shimamoto,Y, AU - Sano,M, AU - Matsuzaki,M, AU - Suga,K, AU - Tokioka,T, AU - Sueoka,E, AU - Ono,K, AU - Yamaguchi,M, AU - Nagumo,F, PY - 1989/10/1/pubmed PY - 1989/10/1/medline PY - 1989/10/1/entrez SP - 1810 EP - 4 JF - [Rinsho ketsueki] The Japanese journal of clinical hematology JO - Rinsho Ketsueki VL - 30 IS - 10 N2 - In this paper is reported a case of acute biphenotypic leukemia who was treated by chemotherapy and pursued its effect by two color flow cytometry. A 33-year-old male patient was admitted due to fever and general fatigue and diagnosed as acute leukemia by hematological findings. Surface markers were investigated to find positive reaction of Leu 12 (CD19), J 5 (CD10), My 7 (CD13) and My 9 (CD33), in which Leu 12 and My 9 were simultaneously expressed on the same blast cells by two color flow cytometry. He was treated with daunorubicin, enocitabine, mercaptopurine, vincristine, and prednisolone to obtain partial remission. Then, he was administered L-asparaginase, doxorubicin, vincristine and prednisolone to reach complete remission. The effect of chemotherapy was investigated by not only bone marrow puncture, but also by two color flow cytometry. From the findings in this case, the two flow cytometry was proved to be a useful tool for not only diagnosis of acute mixed leukemia, aut also the judgement of the effect of treatment. SN - 0485-1439 UR - https://www.unboundmedicine.com/medline/citation/2593247/[Acute_biphenotypic_leukemia_followed_by_two_color_flow_cytometry]_ L2 - http://www.diseaseinfosearch.org/result/179 DB - PRIME DP - Unbound Medicine ER -