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Statins and diabetes.
Cardiol Clin 2015; 33(2):233-43CC

Abstract

A statin is first-line drug therapy for dyslipidemia. Clinical trial data suggest there is an increase in the incidence of new-onset type 2 diabetes mellitus with statin use. The National Lipid Association (NLA) Statin Diabetes Safety Task Force concluded that the cardiovascular benefit of statin therapy outweighs the risk for developing diabetes. The NLA panel advocated following the standards of care from the American Diabetes Association for screening and diagnosis of diabetes, and emphasized the importance of lifestyle modification. This article summarizes NLA's review of the evidence, expanding it to include recent results, and outlines the clinical recommendations.

Authors+Show Affiliations

Metabolic Sciences, Midwest Center for Metabolic & Cardiovascular Research, 489 Taft Avenue, Suite 202, Glen Ellyn, IL 60137, USA. Electronic address: kmaki@mc-mcr.com.Metabolic Sciences, Midwest Center for Metabolic & Cardiovascular Research, 489 Taft Avenue, Suite 202, Glen Ellyn, IL 60137, USA.Division of Medicine, Charles E. Schmidt College of Biomedical Science, Florida Atlantic University, 777 Glades Road, Boca Raton, FL 33431, USA.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

25939296

Citation

Maki, Kevin C., et al. "Statins and Diabetes." Cardiology Clinics, vol. 33, no. 2, 2015, pp. 233-43.
Maki KC, Dicklin MR, Baum SJ. Statins and diabetes. Cardiol Clin. 2015;33(2):233-43.
Maki, K. C., Dicklin, M. R., & Baum, S. J. (2015). Statins and diabetes. Cardiology Clinics, 33(2), pp. 233-43. doi:10.1016/j.ccl.2015.02.004.
Maki KC, Dicklin MR, Baum SJ. Statins and Diabetes. Cardiol Clin. 2015;33(2):233-43. PubMed PMID: 25939296.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Statins and diabetes. AU - Maki,Kevin C, AU - Dicklin,Mary R, AU - Baum,Seth J, PY - 2015/5/6/entrez PY - 2015/5/6/pubmed PY - 2016/1/27/medline KW - Cardiovascular disease KW - Coronary heart disease KW - Diabetes mellitus KW - Dyslipidemia KW - Glucose KW - Glycemia KW - High intensity statins KW - Statins SP - 233 EP - 43 JF - Cardiology clinics JO - Cardiol Clin VL - 33 IS - 2 N2 - A statin is first-line drug therapy for dyslipidemia. Clinical trial data suggest there is an increase in the incidence of new-onset type 2 diabetes mellitus with statin use. The National Lipid Association (NLA) Statin Diabetes Safety Task Force concluded that the cardiovascular benefit of statin therapy outweighs the risk for developing diabetes. The NLA panel advocated following the standards of care from the American Diabetes Association for screening and diagnosis of diabetes, and emphasized the importance of lifestyle modification. This article summarizes NLA's review of the evidence, expanding it to include recent results, and outlines the clinical recommendations. SN - 1558-2264 UR - https://www.unboundmedicine.com/medline/citation/25939296/Statins_and_diabetes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0733-8651(15)00010-7 DB - PRIME DP - Unbound Medicine ER -