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Does beer, wine or liquor consumption correlate with the risk of renal cell carcinoma? A dose-response meta-analysis of prospective cohort studies.
Oncotarget. 2015 May 30; 6(15):13347-58.O

Abstract

Despite plenty of evidence supports an inverse association between alcohol drinking and risk of renal cell carcinoma (RCC), sex-specific and beverage-specific dose-response relationships have not been well established. We examined this association by performing a systematic review and meta-analysis of prospective studies. Studies were identified by comprehensively searching PubMed and EMBASE databases through February 21, 2015. Categorical and dose-response meta-analyses were conducted to identify the effects of alcohol on RCC. A total of eight publications (including seven cohort studies and one pooled analysis of 12 cohort studies) were eligible for this meta-analysis. Dose-response analysis showed that each 5 g/day increment of alcohol intake corresponded to a 5% decrease in risk of RCC for males and 9% for females. Alcohol intakes from wine, beer, and liquor were each associated with a reduced risk of RCC. When these associations were examined separately by gender, statistically significant inverse associations were restricted to alcohol from wine among females (RR = 0.82, 95% CI 0.73-0.91) and to alcohol from beer and from liquor among males (RR = 0.87, 95% CI 0.83-0.91 and RR = 0.95, 95% CI 0.92-0.99, respectively). In conclusion, there exist gender-specific and beverage-specific differences in the association between alcohol intake and RCC risk.

Authors+Show Affiliations

Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Pub Type(s)

Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Systematic Review

Language

eng

PubMed ID

25965820

Citation

Xu, Xin, et al. "Does Beer, Wine or Liquor Consumption Correlate With the Risk of Renal Cell Carcinoma? a Dose-response Meta-analysis of Prospective Cohort Studies." Oncotarget, vol. 6, no. 15, 2015, pp. 13347-58.
Xu X, Zhu Y, Zheng X, et al. Does beer, wine or liquor consumption correlate with the risk of renal cell carcinoma? A dose-response meta-analysis of prospective cohort studies. Oncotarget. 2015;6(15):13347-58.
Xu, X., Zhu, Y., Zheng, X., & Xie, L. (2015). Does beer, wine or liquor consumption correlate with the risk of renal cell carcinoma? A dose-response meta-analysis of prospective cohort studies. Oncotarget, 6(15), 13347-58.
Xu X, et al. Does Beer, Wine or Liquor Consumption Correlate With the Risk of Renal Cell Carcinoma? a Dose-response Meta-analysis of Prospective Cohort Studies. Oncotarget. 2015 May 30;6(15):13347-58. PubMed PMID: 25965820.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does beer, wine or liquor consumption correlate with the risk of renal cell carcinoma? A dose-response meta-analysis of prospective cohort studies. AU - Xu,Xin, AU - Zhu,Yi, AU - Zheng,Xiangyi, AU - Xie,Liping, PY - 2015/02/24/received PY - 2015/04/15/accepted PY - 2015/5/13/entrez PY - 2015/5/13/pubmed PY - 2016/4/8/medline KW - alcohol KW - epidemiology KW - meta-analysis KW - renal cell carcinoma KW - risk factor SP - 13347 EP - 58 JF - Oncotarget JO - Oncotarget VL - 6 IS - 15 N2 - Despite plenty of evidence supports an inverse association between alcohol drinking and risk of renal cell carcinoma (RCC), sex-specific and beverage-specific dose-response relationships have not been well established. We examined this association by performing a systematic review and meta-analysis of prospective studies. Studies were identified by comprehensively searching PubMed and EMBASE databases through February 21, 2015. Categorical and dose-response meta-analyses were conducted to identify the effects of alcohol on RCC. A total of eight publications (including seven cohort studies and one pooled analysis of 12 cohort studies) were eligible for this meta-analysis. Dose-response analysis showed that each 5 g/day increment of alcohol intake corresponded to a 5% decrease in risk of RCC for males and 9% for females. Alcohol intakes from wine, beer, and liquor were each associated with a reduced risk of RCC. When these associations were examined separately by gender, statistically significant inverse associations were restricted to alcohol from wine among females (RR = 0.82, 95% CI 0.73-0.91) and to alcohol from beer and from liquor among males (RR = 0.87, 95% CI 0.83-0.91 and RR = 0.95, 95% CI 0.92-0.99, respectively). In conclusion, there exist gender-specific and beverage-specific differences in the association between alcohol intake and RCC risk. SN - 1949-2553 UR - https://www.unboundmedicine.com/medline/citation/25965820/Does_beer_wine_or_liquor_consumption_correlate_with_the_risk_of_renal_cell_carcinoma_A_dose_response_meta_analysis_of_prospective_cohort_studies_ L2 - https://www.oncotarget.com/lookup/doi/10.18632/oncotarget.3749 DB - PRIME DP - Unbound Medicine ER -