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Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder.
Biomed Res Int 2015; 2015:735615BR

Abstract

Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D deficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.

Authors+Show Affiliations

Department of Internal Medicine and Biomedicine, University of Palermo, 90100 Palermo, Italy.Department of Internal Medicine and Biomedicine, University of Palermo, 90100 Palermo, Italy.Department of Internal Medicine and Biomedicine, University of Palermo, 90100 Palermo, Italy.Department of Human Pathology, University of Messina, 98125 Messina, Italy ; IFC CNR, Messina Unit, 98100 Messina, Italy.Infectious Diseases Unit, Papardo-Piemonte Hospital, 98125 Messina, Italy.Department of Human Pathology, University of Messina, 98125 Messina, Italy ; AILMI-ONLUS Italian Association for the Control of Infectious Diseases, University of Messina, 98125 Messina, Italy.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26000302

Citation

Mansueto, Pasquale, et al. "Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder." BioMed Research International, vol. 2015, 2015, p. 735615.
Mansueto P, Seidita A, Vitale G, et al. Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder. Biomed Res Int. 2015;2015:735615.
Mansueto, P., Seidita, A., Vitale, G., Gangemi, S., Iaria, C., & Cascio, A. (2015). Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder. BioMed Research International, 2015, p. 735615. doi:10.1155/2015/735615.
Mansueto P, et al. Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder. Biomed Res Int. 2015;2015:735615. PubMed PMID: 26000302.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder. AU - Mansueto,Pasquale, AU - Seidita,Aurelio, AU - Vitale,Giustina, AU - Gangemi,Sebastiano, AU - Iaria,Chiara, AU - Cascio,Antonio, Y1 - 2015/04/27/ PY - 2014/11/19/received PY - 2015/02/18/revised PY - 2015/03/02/accepted PY - 2015/5/23/entrez PY - 2015/5/23/pubmed PY - 2016/2/16/medline SP - 735615 EP - 735615 JF - BioMed research international JO - Biomed Res Int VL - 2015 N2 - Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D deficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects. SN - 2314-6141 UR - https://www.unboundmedicine.com/medline/citation/26000302/full_citation L2 - https://dx.doi.org/10.1155/2015/735615 DB - PRIME DP - Unbound Medicine ER -