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Stenotrophomonas maltophilia keratitis treated with trimethoprim-sulfamethoxazole.
Arch Soc Esp Oftalmol. 2015 Nov; 90(11):539-41.AS

Abstract

CASE REPORT

An 84 year-old woman with persistent epithelial defect and a dense stromal infiltrate post-corneal transplantation. According to the microbiological results, it was due to a Stenotrophomonas maltophilia (S. maltophilia) resistant to all antibiotics except trimethoprim-sulfamethoxazole (TMP/SMX). Healing was achieved after three weeks of treatment with oral and topical TMP/SMX.

DISCUSSION

S. maltophilia is an opportunistic microorganism rarely described in ophthalmology. It is associated with conjunctivitis, keratitis, scleritis, dacryrocystitis, cellulitis, and endophthalmitis with significant morbidity. Treatment is complicated because of its resistances to broad-spectrum antibiotics. TMP/SMX monotherapy can be considered an option of treatment for this type of keratitis.

Authors+Show Affiliations

Servicio de Oftalmología, Hospital Universitario Ramón y Cajal, Madrid, España. Electronic address: diezalvarezl@gmail.com.Servicio de Oftalmología, Hospital Universitario Ramón y Cajal, Madrid, España.Servicio de Oftalmología, Hospital Universitario Ramón y Cajal, Madrid, España; Clínica Rementería, Madrid, España.

Pub Type(s)

Case Reports
Journal Article

Language

eng spa

PubMed ID

26008926

Citation

Díez-Álvarez, L, et al. "Stenotrophomonas Maltophilia Keratitis Treated With Trimethoprim-sulfamethoxazole." Archivos De La Sociedad Espanola De Oftalmologia, vol. 90, no. 11, 2015, pp. 539-41.
Díez-Álvarez L, Lumbreras-Fernández B, García-Pérez JL. Stenotrophomonas maltophilia keratitis treated with trimethoprim-sulfamethoxazole. Arch Soc Esp Oftalmol. 2015;90(11):539-41.
Díez-Álvarez, L., Lumbreras-Fernández, B., & García-Pérez, J. L. (2015). Stenotrophomonas maltophilia keratitis treated with trimethoprim-sulfamethoxazole. Archivos De La Sociedad Espanola De Oftalmologia, 90(11), 539-41. https://doi.org/10.1016/j.oftal.2015.03.001
Díez-Álvarez L, Lumbreras-Fernández B, García-Pérez JL. Stenotrophomonas Maltophilia Keratitis Treated With Trimethoprim-sulfamethoxazole. Arch Soc Esp Oftalmol. 2015;90(11):539-41. PubMed PMID: 26008926.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Stenotrophomonas maltophilia keratitis treated with trimethoprim-sulfamethoxazole. AU - Díez-Álvarez,L, AU - Lumbreras-Fernández,B, AU - García-Pérez,J L, Y1 - 2015/05/23/ PY - 2014/07/25/received PY - 2015/03/04/revised PY - 2015/03/07/accepted PY - 2015/5/27/entrez PY - 2015/5/27/pubmed PY - 2017/5/23/medline KW - Ciprofloxacin KW - Ciprofloxacino KW - Cornea KW - Córnea KW - Keratitis KW - Queratitis KW - Stenotrophomonas maltophilia KW - Trimethoprim-sulfamethoxazole KW - Trimetoprima-sulfametoxazol SP - 539 EP - 41 JF - Archivos de la Sociedad Espanola de Oftalmologia JO - Arch Soc Esp Oftalmol VL - 90 IS - 11 N2 - CASE REPORT: An 84 year-old woman with persistent epithelial defect and a dense stromal infiltrate post-corneal transplantation. According to the microbiological results, it was due to a Stenotrophomonas maltophilia (S. maltophilia) resistant to all antibiotics except trimethoprim-sulfamethoxazole (TMP/SMX). Healing was achieved after three weeks of treatment with oral and topical TMP/SMX. DISCUSSION: S. maltophilia is an opportunistic microorganism rarely described in ophthalmology. It is associated with conjunctivitis, keratitis, scleritis, dacryrocystitis, cellulitis, and endophthalmitis with significant morbidity. Treatment is complicated because of its resistances to broad-spectrum antibiotics. TMP/SMX monotherapy can be considered an option of treatment for this type of keratitis. SN - 1989-7286 UR - https://www.unboundmedicine.com/medline/citation/26008926/Stenotrophomonas_maltophilia_keratitis_treated_with_trimethoprim_sulfamethoxazole_ L2 - http://www.elsevier.es/en/linksolver/ft/pii/S0365-6691(15)00090-8 DB - PRIME DP - Unbound Medicine ER -