Citation
Yao, Xin, et al. "Enterovirus Spectrum From the Active Surveillance of Hand Foot and Mouth Disease Patients Under the Clinical Trial of Inactivated Enterovirus A71 Vaccine in Jiangsu, China, 2012-2013." Journal of Medical Virology, vol. 87, no. 12, 2015, pp. 2009-17.
Yao X, Bian LL, Lu WW, et al. Enterovirus spectrum from the active surveillance of hand foot and mouth disease patients under the clinical trial of inactivated Enterovirus A71 vaccine in Jiangsu, China, 2012-2013. J Med Virol. 2015;87(12):2009-17.
Yao, X., Bian, L. L., Lu, W. W., Li, J. X., Mao, Q. Y., Wang, Y. P., Gao, F., Wu, X., Ye, Q., Xu, M., Li, X. L., Zhu, F. C., & Liang, Z. L. (2015). Enterovirus spectrum from the active surveillance of hand foot and mouth disease patients under the clinical trial of inactivated Enterovirus A71 vaccine in Jiangsu, China, 2012-2013. Journal of Medical Virology, 87(12), 2009-17. https://doi.org/10.1002/jmv.24275
Yao X, et al. Enterovirus Spectrum From the Active Surveillance of Hand Foot and Mouth Disease Patients Under the Clinical Trial of Inactivated Enterovirus A71 Vaccine in Jiangsu, China, 2012-2013. J Med Virol. 2015;87(12):2009-17. PubMed PMID: 26010334.
TY - JOUR
T1 - Enterovirus spectrum from the active surveillance of hand foot and mouth disease patients under the clinical trial of inactivated Enterovirus A71 vaccine in Jiangsu, China, 2012-2013.
AU - Yao,Xin,
AU - Bian,Lian-Lian,
AU - Lu,Wei-Wei,
AU - Li,Jing-Xin,
AU - Mao,Qun-Ying,
AU - Wang,Yi-Ping,
AU - Gao,Fan,
AU - Wu,Xing,
AU - Ye,Qiang,
AU - Xu,Miao,
AU - Li,Xiu-Ling,
AU - Zhu,Feng-Cai,
AU - Liang,Zheng-Lun,
Y1 - 2015/06/09/
PY - 2015/05/19/accepted
PY - 2015/5/27/entrez
PY - 2015/5/27/pubmed
PY - 2016/7/23/medline
KW - coxsackievirus A16
KW - enterovirus 71
KW - enterovirus spectrum
KW - hand, foot, and mouth disease
KW - human enteroviruses
SP - 2009
EP - 17
JF - Journal of medical virology
JO - J Med Virol
VL - 87
IS - 12
N2 - Epidemiological data from active surveillance on human enterovirus, which could cause hand, foot, and mouth disease, were limited. An active surveillance system was used to investigate the enterovirus spectrum and the incidence of different enteroviruses in infants aged 6-35 months in Jiangsu Province from 2012 to 2013. Fifty-nine infants were randomly selected from 522 non-EV-A71/CV-A16 HFMD patients. We collected 173 throat swabs and 174 rectal swabs from these infants. RT-PCR was used to amplify 5'-UTR and VP1 regions of enteroviruses and the serotypes were determined by the sequence comparison using BLAST. Twenty-one non-EV-A71/CA16 enterovirus serotypes were detected in those infants. E16, E18 were firstly reported in HFMD patients. The four top common non-EV-A71/CV-A enteroviruses among infants were CV-B3, CV-A10, CV-A6, and E9 with the HFMD incidence rates at 1.4%, 0.84%, 0.56%, and 0.47%, respectively. Over 20.8% patients were co-infected with multiple enteroviruses. Neither the course of sickness nor clinical symptoms of the co-infected patients was more severe than those infected with single enterovirus. Two patients were infected different enterovirus successively within 2 months. Several new enterovirus serotypes and multiple models of infection associated with HFMD were discovered through the active surveillance system. These data provide a better understanding of the viral etiology of HFMD.
SN - 1096-9071
UR - https://www.unboundmedicine.com/medline/citation/26010334/Enterovirus_spectrum_from_the_active_surveillance_of_hand_foot_and_mouth_disease_patients_under_the_clinical_trial_of_inactivated_Enterovirus_A71_vaccine_in_Jiangsu_China_2012_2013_
L2 - https://doi.org/10.1002/jmv.24275
DB - PRIME
DP - Unbound Medicine
ER -
