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[Study on anti-tumor chemical constituents from pericarps of Juglans mandshurica].
Zhong Yao Cai. 2014 Nov; 37(11):1998-2001.ZY

Abstract

OBJECTIVE

To study the anti-tumor chemical components of the pericarps of Juglans mandshurica.

METHODS

The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin, silica gel, Sephadex LH-20 columns and recrystallization. The structures were elucidated on the basis of physicochemical properties and NMR spectral data analysis.

RESULTS

From the pericarps of Juglans mandshurica, twelve compounds were separated and identified as 3-methoxy juglone(1), 3-ethoxy juglone(2), 1,8-di-hydroxy anthraquinone (3), juglone (4), 2α, 3α, 19α-trihydroxy ursolic acid (5), 1α, 3β-dihydroxy-olean-18-ene (6), methyl gallate (7), pterocarine(8), quercetin(9), kaempferol(10), daucosterol(11), and β-sitosterol(12).

CONCLUSION

Compounds 1 - 3 and 6 are isolated from the pericarps of Juglans mandshurica for the first time. Compounds 5 and 7 are isolated from Juglans genus for the first time.

Authors

Zhou YY
No affiliation info available
Meng Y
No affiliation info available
Jiang YQ
No affiliation info available
Liu ZX
No affiliation info available
Yang BY
No affiliation info available

MeSH

AnthraquinonesAntineoplastic Agents, PhytogenicDrugs, Chinese HerbalGallic AcidJuglansKaempferolsNaphthoquinonesPhytochemicalsSeedsSitosterolsTriterpenes

Pub Type(s)

Journal Article

Language

chi

PubMed ID

26027119

Citation

Zhou, Yuan-yuan, et al. "[Study On Anti-tumor Chemical Constituents From Pericarps of Juglans Mandshurica]." Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, vol. 37, no. 11, 2014, pp. 1998-2001.
Zhou YY, Meng Y, Jiang YQ, et al. [Study on anti-tumor chemical constituents from pericarps of Juglans mandshurica]. Zhong Yao Cai. 2014;37(11):1998-2001.
Zhou, Y. Y., Meng, Y., Jiang, Y. Q., Liu, Z. X., & Yang, B. Y. (2014). [Study on anti-tumor chemical constituents from pericarps of Juglans mandshurica]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, 37(11), 1998-2001.
Zhou YY, et al. [Study On Anti-tumor Chemical Constituents From Pericarps of Juglans Mandshurica]. Zhong Yao Cai. 2014;37(11):1998-2001. PubMed PMID: 26027119.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Study on anti-tumor chemical constituents from pericarps of Juglans mandshurica]. AU - Zhou,Yuan-yuan, AU - Meng,Ying, AU - Jiang,Yan-qiu, AU - Liu,Zhao-xi, AU - Yang,Bing-you, PY - 2015/6/2/entrez PY - 2015/6/2/pubmed PY - 2015/12/17/medline SP - 1998 EP - 2001 JF - Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials JO - Zhong Yao Cai VL - 37 IS - 11 N2 - OBJECTIVE: To study the anti-tumor chemical components of the pericarps of Juglans mandshurica. METHODS: The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin, silica gel, Sephadex LH-20 columns and recrystallization. The structures were elucidated on the basis of physicochemical properties and NMR spectral data analysis. RESULTS: From the pericarps of Juglans mandshurica, twelve compounds were separated and identified as 3-methoxy juglone(1), 3-ethoxy juglone(2), 1,8-di-hydroxy anthraquinone (3), juglone (4), 2α, 3α, 19α-trihydroxy ursolic acid (5), 1α, 3β-dihydroxy-olean-18-ene (6), methyl gallate (7), pterocarine(8), quercetin(9), kaempferol(10), daucosterol(11), and β-sitosterol(12). CONCLUSION: Compounds 1 - 3 and 6 are isolated from the pericarps of Juglans mandshurica for the first time. Compounds 5 and 7 are isolated from Juglans genus for the first time. SN - 1001-4454 UR - https://www.unboundmedicine.com/medline/citation/26027119/[Study_on_anti_tumor_chemical_constituents_from_pericarps_of_Juglans_mandshurica]_ DB - PRIME DP - Unbound Medicine ER -