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Evaluation of antioxidant and α-glucosidase inhibitory activities of some subtropical plants.
Pak J Biol Sci. 2014 Oct; 17(10):1106-14.PJ

Abstract

The antioxidant and α-glucosidase inhibitory activities of the methanolic leaf extracts of some subtropical plants were evaluated in the present study. Antioxidant activity was evaluated based on 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, reducing power, hydrogen peroxide and β-carotene bleaching assays. α-Glucosidase inhibitory activity and enzyme kinetics as well as the total phenolic content of the extracts were also investigated. Elaeocarpus sylvestris extract had the highest activities on all the antioxidant assays performed such as DPPH scavenging activity (IC50 12.7 ± 0.5 μg mL(-1)), reducing power (491.1 ± 6.3 mg QE g(-1) dry extract), hydrogen peroxide (IC50 65.6 ± 0.4 μg mL(-1)) and β-carotene bleaching assays (IC50 5.1 ± 1.9 μg mL(-1)). The total phenolic content of the E. sylvestris extract also had the highest values for gallic acid, quercetin and rutin equivalents (353.8 ± 28.6 mg GAE g(-1) dry extract; 294.9 ± 24.5 mg QE g(-1) dry extract; 663.0 ± 52.3 mg RE g(-1) dry extract, respectively). α-Glucosidase inhibition assay revealed that Distylium racemosum had the highest activity with an IC50 value of 22.6 ± 1.9 μg mL(-1). The results of the present study revealed the potencies of E. sylvestris, D. racemosum, Acer mono Maxim and Liquidambar styraciflua as alternative sources for antioxidants and α-glucosidase inhibitors.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

26027154

Citation

Prihantini, Amalia Indah, et al. "Evaluation of Antioxidant and Α-glucosidase Inhibitory Activities of some Subtropical Plants." Pakistan Journal of Biological Sciences : PJBS, vol. 17, no. 10, 2014, pp. 1106-14.
Prihantini AI, Tachibana S, Itoh K. Evaluation of antioxidant and α-glucosidase inhibitory activities of some subtropical plants. Pak J Biol Sci. 2014;17(10):1106-14.
Prihantini, A. I., Tachibana, S., & Itoh, K. (2014). Evaluation of antioxidant and α-glucosidase inhibitory activities of some subtropical plants. Pakistan Journal of Biological Sciences : PJBS, 17(10), 1106-14.
Prihantini AI, Tachibana S, Itoh K. Evaluation of Antioxidant and Α-glucosidase Inhibitory Activities of some Subtropical Plants. Pak J Biol Sci. 2014;17(10):1106-14. PubMed PMID: 26027154.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of antioxidant and α-glucosidase inhibitory activities of some subtropical plants. AU - Prihantini,Amalia Indah, AU - Tachibana,Sanro, AU - Itoh,Kazutaka, PY - 2015/6/2/entrez PY - 2015/6/2/pubmed PY - 2015/8/1/medline SP - 1106 EP - 14 JF - Pakistan journal of biological sciences : PJBS JO - Pak J Biol Sci VL - 17 IS - 10 N2 - The antioxidant and α-glucosidase inhibitory activities of the methanolic leaf extracts of some subtropical plants were evaluated in the present study. Antioxidant activity was evaluated based on 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, reducing power, hydrogen peroxide and β-carotene bleaching assays. α-Glucosidase inhibitory activity and enzyme kinetics as well as the total phenolic content of the extracts were also investigated. Elaeocarpus sylvestris extract had the highest activities on all the antioxidant assays performed such as DPPH scavenging activity (IC50 12.7 ± 0.5 μg mL(-1)), reducing power (491.1 ± 6.3 mg QE g(-1) dry extract), hydrogen peroxide (IC50 65.6 ± 0.4 μg mL(-1)) and β-carotene bleaching assays (IC50 5.1 ± 1.9 μg mL(-1)). The total phenolic content of the E. sylvestris extract also had the highest values for gallic acid, quercetin and rutin equivalents (353.8 ± 28.6 mg GAE g(-1) dry extract; 294.9 ± 24.5 mg QE g(-1) dry extract; 663.0 ± 52.3 mg RE g(-1) dry extract, respectively). α-Glucosidase inhibition assay revealed that Distylium racemosum had the highest activity with an IC50 value of 22.6 ± 1.9 μg mL(-1). The results of the present study revealed the potencies of E. sylvestris, D. racemosum, Acer mono Maxim and Liquidambar styraciflua as alternative sources for antioxidants and α-glucosidase inhibitors. SN - 1028-8880 UR - https://www.unboundmedicine.com/medline/citation/26027154/Evaluation_of_antioxidant_and_α_glucosidase_inhibitory_activities_of_some_subtropical_plants_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -