Citation
Garcia-Arellano, Ana, et al. "Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study." Nutrients, vol. 7, no. 6, 2015, pp. 4124-38.
Garcia-Arellano A, Ramallal R, Ruiz-Canela M, et al. Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study. Nutrients. 2015;7(6):4124-38.
Garcia-Arellano, A., Ramallal, R., Ruiz-Canela, M., Salas-Salvadó, J., Corella, D., Shivappa, N., Schröder, H., Hébert, J. R., Ros, E., Gómez-Garcia, E., Estruch, R., Lapetra, J., Arós, F., Fiol, M., Serra-Majem, L., Pintó, X., Babio, N., González, J. I., Fitó, M., ... Martínez-González, M. A. (2015). Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study. Nutrients, 7(6), 4124-38. https://doi.org/10.3390/nu7064124
Garcia-Arellano A, et al. Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study. Nutrients. 2015 May 29;7(6):4124-38. PubMed PMID: 26035241.
TY - JOUR
T1 - Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study.
AU - Garcia-Arellano,Ana,
AU - Ramallal,Raul,
AU - Ruiz-Canela,Miguel,
AU - Salas-Salvadó,Jordi,
AU - Corella,Dolores,
AU - Shivappa,Nitin,
AU - Schröder,Helmut,
AU - Hébert,James R,
AU - Ros,Emilio,
AU - Gómez-Garcia,Enrique,
AU - Estruch,Ramon,
AU - Lapetra,José,
AU - Arós,Fernando,
AU - Fiol,Miquel,
AU - Serra-Majem,Lluis,
AU - Pintó,Xavier,
AU - Babio,Nancy,
AU - González,José I,
AU - Fitó,Montse,
AU - Martínez,J Alfredo,
AU - Martínez-González,Miguel A,
AU - ,,
Y1 - 2015/05/29/
PY - 2015/03/12/received
PY - 2015/05/11/revised
PY - 2015/05/18/accepted
PY - 2015/6/3/entrez
PY - 2015/6/4/pubmed
PY - 2016/5/4/medline
KW - PREDIMED
KW - cardiovascular disease
KW - dietary inflammatory index
KW - inflammation
SP - 4124
EP - 38
JF - Nutrients
JO - Nutrients
VL - 7
IS - 6
N2 - Previous studies have reported an association between a more pro-inflammatory diet profile and various chronic metabolic diseases. The Dietary Inflammatory Index (DII) was used to assess the inflammatory potential of nutrients and foods in the context of a dietary pattern. We prospectively examined the association between the DII and the incidence of cardiovascular disease (CVD: myocardial infarction, stroke or cardiovascular death) in the PREDIMED (Prevención con Dieta Mediterránea) study including 7216 high-risk participants. The DII was computed based on a validated 137-item food frequency questionnaire. Multivariate-adjusted hazard ratios (HR) and 95% confidence intervals of CVD risk were computed across quartiles of the DII where the lowest (most anti-inflammatory) quartile is the referent. Risk increased across the quartiles (i.e., with increasing inflammatory potential): HR(quartile2) = 1.42 (95%CI = 0.97-2.09); HR(quartile3) = 1.85 (1.27-2.71); and HR(quartile4) = 1.73 (1.15-2.60). When fit as continuous the multiple-adjusted hazard ratio for each additional standard deviation of the DII was 1.22 (1.06-1.40). Our results provide direct prospective evidence that a pro-inflammatory diet is associated with a higher risk of cardiovascular clinical events.
SN - 2072-6643
UR - https://www.unboundmedicine.com/medline/citation/26035241/Dietary_Inflammatory_Index_and_Incidence_of_Cardiovascular_Disease_in_the_PREDIMED_Study_
DB - PRIME
DP - Unbound Medicine
ER -
