Tags

Type your tag names separated by a space and hit enter

Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis.
PLoS Negl Trop Dis. 2015; 9(6):e0003785.PN

Abstract

BACKGROUND

Over the last few years, momentum has gathered around the feasibility and opportunity of eliminating gambiense human African trypanosomiasis (g-HAT). Under the leadership of the World Health Organization (WHO), a large coalition of stakeholders is now committed to achieving this goal. A roadmap has been laid out, and indicators and milestones have been defined to monitor the progress of the elimination of g-HAT as a public health problem by 2020. Subsequently, a more ambitious objective was set for 2030: to stop disease transmission. This paper provides a situational update to 2012 for a number of indicators of elimination: number of cases annually reported, geographic distribution of the disease and areas and populations at different levels of risk.

RESULTS

Comparing the 5-year periods 2003-2007 and 2008-2012, the area at high or very high risk of g-HAT shrank by 60%, while the area at moderate risk decreased by 22%. These are the areas where g-HAT is still to be considered a public health problem (i.e. > 1 HAT reported case per 10,000 people per annum). This contraction of at-risk areas corresponds to a reduction of 57% for the population at high or very high risk (from 4.1 to 1.8 million), and 20% for moderate risk (from 14.0 to 11.3 million).

DISCUSSION

Improved data completeness and accuracy of the Atlas of HAT enhanced our capacity to monitor the progress towards the elimination of g-HAT. The trends in the selected indicators suggest that, in recent years, progress has been steady and in line with the elimination goal laid out in the WHO roadmap on neglected tropical diseases.

Links

PMC Free PDF

Authors+Show Affiliations

Simarro PP
World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.
Cecchi G
Food and Agriculture Organization of the United Nations, Sub-regional Office for Eastern Africa, Addis Ababa, Ethiopia.
Franco JR
World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.
Paone M
Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy.
Diarra A
World Health Organization, Regional Office for Africa, Intercountry Support Team, Libreville, Gabon.
Priotto G
World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.
Mattioli RC
Food and Agriculture Organization of the United Nations, Animal Production and Health Division, Rome, Italy.
Jannin JG
World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland.

MeSH

Africa South of the SaharaDemographyDisease EradicationDisease Transmission, InfectiousEpidemiological MonitoringGeographyHumansRisk AssessmentTrypanosoma brucei gambienseTrypanosomiasis, African

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26056823

Citation

Simarro, Pere P., et al. "Monitoring the Progress Towards the Elimination of Gambiense Human African Trypanosomiasis." PLoS Neglected Tropical Diseases, vol. 9, no. 6, 2015, pp. e0003785.
Simarro PP, Cecchi G, Franco JR, et al. Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis. PLoS Negl Trop Dis. 2015;9(6):e0003785.
Simarro, P. P., Cecchi, G., Franco, J. R., Paone, M., Diarra, A., Priotto, G., Mattioli, R. C., & Jannin, J. G. (2015). Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis. PLoS Neglected Tropical Diseases, 9(6), e0003785. https://doi.org/10.1371/journal.pntd.0003785
Simarro PP, et al. Monitoring the Progress Towards the Elimination of Gambiense Human African Trypanosomiasis. PLoS Negl Trop Dis. 2015;9(6):e0003785. PubMed PMID: 26056823.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Monitoring the Progress towards the Elimination of Gambiense Human African Trypanosomiasis. AU - Simarro,Pere P, AU - Cecchi,Giuliano, AU - Franco,José R, AU - Paone,Massimo, AU - Diarra,Abdoulaye, AU - Priotto,Gerardo, AU - Mattioli,Raffaele C, AU - Jannin,Jean G, Y1 - 2015/06/09/ PY - 2015/02/09/received PY - 2015/04/24/accepted PY - 2015/6/10/entrez PY - 2015/6/10/pubmed PY - 2016/3/10/medline SP - e0003785 EP - e0003785 JF - PLoS neglected tropical diseases JO - PLoS Negl Trop Dis VL - 9 IS - 6 N2 - BACKGROUND: Over the last few years, momentum has gathered around the feasibility and opportunity of eliminating gambiense human African trypanosomiasis (g-HAT). Under the leadership of the World Health Organization (WHO), a large coalition of stakeholders is now committed to achieving this goal. A roadmap has been laid out, and indicators and milestones have been defined to monitor the progress of the elimination of g-HAT as a public health problem by 2020. Subsequently, a more ambitious objective was set for 2030: to stop disease transmission. This paper provides a situational update to 2012 for a number of indicators of elimination: number of cases annually reported, geographic distribution of the disease and areas and populations at different levels of risk. RESULTS: Comparing the 5-year periods 2003-2007 and 2008-2012, the area at high or very high risk of g-HAT shrank by 60%, while the area at moderate risk decreased by 22%. These are the areas where g-HAT is still to be considered a public health problem (i.e. > 1 HAT reported case per 10,000 people per annum). This contraction of at-risk areas corresponds to a reduction of 57% for the population at high or very high risk (from 4.1 to 1.8 million), and 20% for moderate risk (from 14.0 to 11.3 million). DISCUSSION: Improved data completeness and accuracy of the Atlas of HAT enhanced our capacity to monitor the progress towards the elimination of g-HAT. The trends in the selected indicators suggest that, in recent years, progress has been steady and in line with the elimination goal laid out in the WHO roadmap on neglected tropical diseases. SN - 1935-2735 UR - https://www.unboundmedicine.com/medline/citation/26056823/Monitoring_the_Progress_towards_the_Elimination_of_Gambiense_Human_African_Trypanosomiasis_ DB - PRIME DP - Unbound Medicine ER -