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First report of autochthonous transmission of Zika virus in Brazil.
Mem Inst Oswaldo Cruz 2015; 110(4):569-72MI

Abstract

In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil.

Authors+Show Affiliations

Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fundação Oswaldo Cruz, Curitiba, PR, Brasil.Secretaria Estadual de Saúde do Rio Grande do Norte, Natal, RN, Brasil.Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fundação Oswaldo Cruz, Curitiba, PR, Brasil.Secretaria Estadual de Saúde do Rio Grande do Norte, Natal, RN, Brasil.Laboratório de Virologia Molecular, Instituto Carlos Chagas, Fundação Oswaldo Cruz, Curitiba, PR, Brasil.Instituto de Medicina Tropical, Universidade Federal do Rio Grande do Norte, Natal, RN, Brasil.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26061233

Citation

Zanluca, Camila, et al. "First Report of Autochthonous Transmission of Zika Virus in Brazil." Memorias Do Instituto Oswaldo Cruz, vol. 110, no. 4, 2015, pp. 569-72.
Zanluca C, Melo VC, Mosimann AL, et al. First report of autochthonous transmission of Zika virus in Brazil. Mem Inst Oswaldo Cruz. 2015;110(4):569-72.
Zanluca, C., Melo, V. C., Mosimann, A. L., Santos, G. I., Santos, C. N., & Luz, K. (2015). First report of autochthonous transmission of Zika virus in Brazil. Memorias Do Instituto Oswaldo Cruz, 110(4), pp. 569-72. doi:10.1590/0074-02760150192.
Zanluca C, et al. First Report of Autochthonous Transmission of Zika Virus in Brazil. Mem Inst Oswaldo Cruz. 2015;110(4):569-72. PubMed PMID: 26061233.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - First report of autochthonous transmission of Zika virus in Brazil. AU - Zanluca,Camila, AU - Melo,Vanessa Campos Andrade de, AU - Mosimann,Ana Luiza Pamplona, AU - Santos,Glauco Igor Viana Dos, AU - Santos,Claudia Nunes Duarte Dos, AU - Luz,Kleber, Y1 - 2015/06/09/ PY - 2015/05/17/received PY - 2015/05/25/accepted PY - 2015/6/11/entrez PY - 2015/6/11/pubmed PY - 2016/3/5/medline SP - 569 EP - 72 JF - Memorias do Instituto Oswaldo Cruz JO - Mem. Inst. Oswaldo Cruz VL - 110 IS - 4 N2 - In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular and serological diagnosis for dengue resulted negative. Chikungunya virus infection was also discarded. Subsequently, Zika virus (ZIKV) was detected by reverse transcription-polymerase chain reaction from the sera of eight patients and the result was confirmed by DNA sequencing. Phylogenetic analysis suggests that the ZIKV identified belongs to the Asian clade. This is the first report of ZIKV infection in Brazil. SN - 1678-8060 UR - https://www.unboundmedicine.com/medline/citation/26061233/First_report_of_autochthonous_transmission_of_Zika_virus_in_Brazil_ L2 - http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015005050192&lng=en&nrm=iso&tlng=en DB - PRIME DP - Unbound Medicine ER -