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Reevaluation of the utility of mean cell hemoglobin (MCH) screening in infants for iron deficiency.
Nouv Rev Fr Hematol 1989; 31(4):307-9NR

Abstract

Iron deficiency (ID) at the stage of latent deficiency (LID) or frank anemia (IDA) is still common in pediatric practice. We have assessed the prevalence of LID and IDA in an infant population with an age range of 9-11 months, in Paris. Red cell indices, hemoglobin level, serum iron, transferrin saturation and serum ferritin levels were assayed. There was considerable prevalence of ID as 82% of the children exhibited low levels in one of the above parameters. We found low mean cell hemoglobin (MCH) to be predictive of LID in one third of cases. Since MCH value is routinely available to the physician, it appears that a close examination of this red cell index should allow for the diagnosis of ID in a large number of children at risk, without the need to resort to more elaborate and expensive laboratory tests.

Authors+Show Affiliations

Département de Pédiatrie, Hôpital du Kremlin-Bicêtre, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2608441

Citation

Archambeaud-Breton, M P., et al. "Reevaluation of the Utility of Mean Cell Hemoglobin (MCH) Screening in Infants for Iron Deficiency." Nouvelle Revue Francaise D'hematologie, vol. 31, no. 4, 1989, pp. 307-9.
Archambeaud-Breton MP, Dommergues JP, Ducot B, et al. Reevaluation of the utility of mean cell hemoglobin (MCH) screening in infants for iron deficiency. Nouv Rev Fr Hematol. 1989;31(4):307-9.
Archambeaud-Breton, M. P., Dommergues, J. P., Ducot, B., Rossignol, C., Yvart, J., & Tchernia, G. (1989). Reevaluation of the utility of mean cell hemoglobin (MCH) screening in infants for iron deficiency. Nouvelle Revue Francaise D'hematologie, 31(4), pp. 307-9.
Archambeaud-Breton MP, et al. Reevaluation of the Utility of Mean Cell Hemoglobin (MCH) Screening in Infants for Iron Deficiency. Nouv Rev Fr Hematol. 1989;31(4):307-9. PubMed PMID: 2608441.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reevaluation of the utility of mean cell hemoglobin (MCH) screening in infants for iron deficiency. AU - Archambeaud-Breton,M P, AU - Dommergues,J P, AU - Ducot,B, AU - Rossignol,C, AU - Yvart,J, AU - Tchernia,G, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 307 EP - 9 JF - Nouvelle revue francaise d'hematologie JO - Nouv Rev Fr Hematol VL - 31 IS - 4 N2 - Iron deficiency (ID) at the stage of latent deficiency (LID) or frank anemia (IDA) is still common in pediatric practice. We have assessed the prevalence of LID and IDA in an infant population with an age range of 9-11 months, in Paris. Red cell indices, hemoglobin level, serum iron, transferrin saturation and serum ferritin levels were assayed. There was considerable prevalence of ID as 82% of the children exhibited low levels in one of the above parameters. We found low mean cell hemoglobin (MCH) to be predictive of LID in one third of cases. Since MCH value is routinely available to the physician, it appears that a close examination of this red cell index should allow for the diagnosis of ID in a large number of children at risk, without the need to resort to more elaborate and expensive laboratory tests. UR - https://www.unboundmedicine.com/medline/citation/2608441/Reevaluation_of_the_utility_of_mean_cell_hemoglobin__MCH__screening_in_infants_for_iron_deficiency_ L2 - https://medlineplus.gov/iron.html DB - PRIME DP - Unbound Medicine ER -