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Negative impacts of ultraviolet-A radiation on antioxidant and oxidative stress biomarkers of African catfish Clarias gariepinus.
Photochem Photobiol Sci. 2015 Jul; 14(7):1337-45.PP

Abstract

The present study was carried out to evaluate the ultraviolet-A (UVA) effects on biochemical, oxidative stress and antioxidant changes using aquatic species. The destructive effects of ultraviolet-A radiation on the African Catfish, Clarias gariepinus was revealed in terms of the carbonyl protein (CP), lipid peroxidation (LPO), DNA damage, super oxide dismutase (SOD), catalase (CAT), glutathione peroxidase (Gpx), glutathione reductase (GR), glucose-6-phosphate dehydrogenase (G6PDH), lactate dehydrogenase (LDH), glutathione (GSH) and total antioxidant (TAO) in the gills, kidney, liver, muscles and skin. Also, glucose, total lipid, total protein and cortisol content of fish serums was detected. These parameters can be used as biomarkers to identify the negative effects of UVA radiation (20, 60 and 180 min per day) for 3 days in different tissues of Clarias gariepinus. There was a significant decrease in the activity of SOD, CAT, Gpx, GSH, G6PDH, LDH, and TAO in all of the examined tissues. The pattern of GR activity in UVA exposed groups showed no significant differences compared with the control group. However, CP, LPO and DNA damage were increased significantly with exposure periods in all of the examined tissues. The exposure to different doses of UVA caused hypoglycaemia, hypolipidimia and hypoproteinimia. Cortisol levels showed a significant increase after UV exposure when compared with the control group. In conclusion, UVA exposure with different time periods has been shown to have negative effects on the blood biochemistry, hormonal and antioxidant capacity of Clarias gariepinus tissues.

Authors+Show Affiliations

Zoology Department, Faculty of Science (New Valley Branch), Assiut University, Egypt. Ahmedt1983@yahoo.com Ahmedt1983@gmail.com Ahmedt1983@scinv.au.edu.eg.

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

26084758

Citation

Ibrahim, Ahmed Th A.. "Negative Impacts of ultraviolet-A Radiation On Antioxidant and Oxidative Stress Biomarkers of African Catfish Clarias Gariepinus." Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology, vol. 14, no. 7, 2015, pp. 1337-45.
Ibrahim AT. Negative impacts of ultraviolet-A radiation on antioxidant and oxidative stress biomarkers of African catfish Clarias gariepinus. Photochem Photobiol Sci. 2015;14(7):1337-45.
Ibrahim, A. T. (2015). Negative impacts of ultraviolet-A radiation on antioxidant and oxidative stress biomarkers of African catfish Clarias gariepinus. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology, 14(7), 1337-45. https://doi.org/10.1039/c5pp00112a
Ibrahim AT. Negative Impacts of ultraviolet-A Radiation On Antioxidant and Oxidative Stress Biomarkers of African Catfish Clarias Gariepinus. Photochem Photobiol Sci. 2015;14(7):1337-45. PubMed PMID: 26084758.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Negative impacts of ultraviolet-A radiation on antioxidant and oxidative stress biomarkers of African catfish Clarias gariepinus. A1 - Ibrahim,Ahmed Th A, PY - 2015/6/19/entrez PY - 2015/6/19/pubmed PY - 2016/3/30/medline SP - 1337 EP - 45 JF - Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology JO - Photochem Photobiol Sci VL - 14 IS - 7 N2 - The present study was carried out to evaluate the ultraviolet-A (UVA) effects on biochemical, oxidative stress and antioxidant changes using aquatic species. The destructive effects of ultraviolet-A radiation on the African Catfish, Clarias gariepinus was revealed in terms of the carbonyl protein (CP), lipid peroxidation (LPO), DNA damage, super oxide dismutase (SOD), catalase (CAT), glutathione peroxidase (Gpx), glutathione reductase (GR), glucose-6-phosphate dehydrogenase (G6PDH), lactate dehydrogenase (LDH), glutathione (GSH) and total antioxidant (TAO) in the gills, kidney, liver, muscles and skin. Also, glucose, total lipid, total protein and cortisol content of fish serums was detected. These parameters can be used as biomarkers to identify the negative effects of UVA radiation (20, 60 and 180 min per day) for 3 days in different tissues of Clarias gariepinus. There was a significant decrease in the activity of SOD, CAT, Gpx, GSH, G6PDH, LDH, and TAO in all of the examined tissues. The pattern of GR activity in UVA exposed groups showed no significant differences compared with the control group. However, CP, LPO and DNA damage were increased significantly with exposure periods in all of the examined tissues. The exposure to different doses of UVA caused hypoglycaemia, hypolipidimia and hypoproteinimia. Cortisol levels showed a significant increase after UV exposure when compared with the control group. In conclusion, UVA exposure with different time periods has been shown to have negative effects on the blood biochemistry, hormonal and antioxidant capacity of Clarias gariepinus tissues. SN - 1474-9092 UR - https://www.unboundmedicine.com/medline/citation/26084758/Negative_impacts_of_ultraviolet_A_radiation_on_antioxidant_and_oxidative_stress_biomarkers_of_African_catfish_Clarias_gariepinus_ L2 - https://doi.org/10.1039/c5pp00112a DB - PRIME DP - Unbound Medicine ER -