Tags

Type your tag names separated by a space and hit enter

Symbiotics in irritable bowel syndrome--better than probiotics alone?
Curr Opin Clin Nutr Metab Care 2015; 18(5):485-9CO

Abstract

PURPOSE OF REVIEW

Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder associated with significant physical and psychological comorbidity. The etiology of the condition is uncertain but recent research suggests that the gut bacterial composition may play a role in its development. Therefore, manipulation of the intestinal microbiome by using probiotics and symbiotics has the potential to improve patient outcomes in IBS.

RECENT FINDINGS

Numerous randomized controlled trials suggest a benefit of probiotics in the management of IBS, with a significant reduction in the likelihood of symptoms persisting after therapy, and improvements in abdominal pain, bloating and flatulence when probiotics are compared with placebo. Evidence for the effect of probiotics on quality of life is conflicting. Relatively few randomized controlled trials have examined the effect of symbiotics on outcomes in IBS, but results thus far are promising.

SUMMARY

Probiotics appear to be beneficial in IBS. Data supporting the use of symbiotics is sparse. Whether symbiotics are superior to probiotics is unclear.

Authors+Show Affiliations

aLeeds Gastroenterology Institute, St. James's University Hospital bLeeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26107141

Citation

Gracie, David J., and Alexander C. Ford. "Symbiotics in Irritable Bowel Syndrome--better Than Probiotics Alone?" Current Opinion in Clinical Nutrition and Metabolic Care, vol. 18, no. 5, 2015, pp. 485-9.
Gracie DJ, Ford AC. Symbiotics in irritable bowel syndrome--better than probiotics alone? Curr Opin Clin Nutr Metab Care. 2015;18(5):485-9.
Gracie, D. J., & Ford, A. C. (2015). Symbiotics in irritable bowel syndrome--better than probiotics alone? Current Opinion in Clinical Nutrition and Metabolic Care, 18(5), pp. 485-9. doi:10.1097/MCO.0000000000000199.
Gracie DJ, Ford AC. Symbiotics in Irritable Bowel Syndrome--better Than Probiotics Alone. Curr Opin Clin Nutr Metab Care. 2015;18(5):485-9. PubMed PMID: 26107141.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Symbiotics in irritable bowel syndrome--better than probiotics alone? AU - Gracie,David J, AU - Ford,Alexander C, PY - 2015/6/25/entrez PY - 2015/6/25/pubmed PY - 2016/5/3/medline SP - 485 EP - 9 JF - Current opinion in clinical nutrition and metabolic care JO - Curr Opin Clin Nutr Metab Care VL - 18 IS - 5 N2 - PURPOSE OF REVIEW: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder associated with significant physical and psychological comorbidity. The etiology of the condition is uncertain but recent research suggests that the gut bacterial composition may play a role in its development. Therefore, manipulation of the intestinal microbiome by using probiotics and symbiotics has the potential to improve patient outcomes in IBS. RECENT FINDINGS: Numerous randomized controlled trials suggest a benefit of probiotics in the management of IBS, with a significant reduction in the likelihood of symptoms persisting after therapy, and improvements in abdominal pain, bloating and flatulence when probiotics are compared with placebo. Evidence for the effect of probiotics on quality of life is conflicting. Relatively few randomized controlled trials have examined the effect of symbiotics on outcomes in IBS, but results thus far are promising. SUMMARY: Probiotics appear to be beneficial in IBS. Data supporting the use of symbiotics is sparse. Whether symbiotics are superior to probiotics is unclear. SN - 1473-6519 UR - https://www.unboundmedicine.com/medline/citation/26107141/Symbiotics_in_irritable_bowel_syndrome__better_than_probiotics_alone L2 - http://Insights.ovid.com/pubmed?pmid=26107141 DB - PRIME DP - Unbound Medicine ER -