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Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.
World J Gastroenterol. 2015 Jun 21; 21(23):7225-32.WJ

Abstract

AIM

To compare the clinicopathological features of patients with non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer.

METHODS

All the patients with rectosigmoid carcinoma who underwent laparoscopic radical surgical resection in the Shanghai Minimally Invasive Surgical Center at Ruijin Hospital affiliated to Shanghai Jiao-Tong University between October 2009 and October 2013 were included in this study. Twenty-six cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected. Symptoms, endoscopic findings and clinicopathological characteristics were evaluated retrospectively.

RESULTS

There were no significant differences between patients with and without schistosomiasis in gender, age, CEA, CA19-9, preoperative biopsy findings or postoperative pathology. Patients with rectosigmoid schistosomiasis had a significantly higher CA-125 level and a larger proportion of these patients were at an early tumor stage (P = 0.003). Various morphological characteristics of schistosomiasis combined with rectosigmoid cancer could be found by colonoscopic examination: 46% were fungating mass polyps, 23% were congestive and ulcerative polyps, 23% were cauliflower-like masses, 8% were annular masses. Only 27% of the patients were diagnosed with rectal carcinoma preoperatively after the biopsy. Computed tomography (CT) scans showed thickened intestinal walls combined with linear and tram-track calcifications in 26 patients.

CONCLUSION

Rectosigmoid carcinoma combined with schistosomiasis is associated with higher CA-125 values and early tumor stages. CA-125 and CT scans have a reasonable sensitivity for the accurate diagnosis.

Authors+Show Affiliations

Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.Hao Feng, Tobias S Schiergens, Serene ML Lee, Wolfgang E Thasler, Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

26109809

Citation

Feng, Hao, et al. "Comparison of Non-schistosomal Rectosigmoid Cancer and Schistosomal Rectosigmoid Cancer." World Journal of Gastroenterology, vol. 21, no. 23, 2015, pp. 7225-32.
Feng H, Lu AG, Zhao XW, et al. Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer. World J Gastroenterol. 2015;21(23):7225-32.
Feng, H., Lu, A. G., Zhao, X. W., Han, D. P., Zhao, J. K., Shi, L., Schiergens, T. S., Lee, S. M., Zhang, W. P., & Thasler, W. E. (2015). Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer. World Journal of Gastroenterology, 21(23), 7225-32. https://doi.org/10.3748/wjg.v21.i23.7225
Feng H, et al. Comparison of Non-schistosomal Rectosigmoid Cancer and Schistosomal Rectosigmoid Cancer. World J Gastroenterol. 2015 Jun 21;21(23):7225-32. PubMed PMID: 26109809.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer. AU - Feng,Hao, AU - Lu,Ai-Guo, AU - Zhao,Xue-Wei, AU - Han,Ding-Pei, AU - Zhao,Jing-Kun, AU - Shi,Lei, AU - Schiergens,Tobias S, AU - Lee,Serene M L, AU - Zhang,Wen-Peng, AU - Thasler,Wolfgang E, PY - 2015/01/06/received PY - 2015/03/13/revised PY - 2015/04/28/accepted PY - 2015/6/26/entrez PY - 2015/6/26/pubmed PY - 2016/3/30/medline KW - Biomarker KW - Colonoscopy KW - Diagnosis KW - Rectosigmoid cancer KW - Schistosomiasis SP - 7225 EP - 32 JF - World journal of gastroenterology JO - World J. Gastroenterol. VL - 21 IS - 23 N2 - AIM: To compare the clinicopathological features of patients with non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer. METHODS: All the patients with rectosigmoid carcinoma who underwent laparoscopic radical surgical resection in the Shanghai Minimally Invasive Surgical Center at Ruijin Hospital affiliated to Shanghai Jiao-Tong University between October 2009 and October 2013 were included in this study. Twenty-six cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected. Symptoms, endoscopic findings and clinicopathological characteristics were evaluated retrospectively. RESULTS: There were no significant differences between patients with and without schistosomiasis in gender, age, CEA, CA19-9, preoperative biopsy findings or postoperative pathology. Patients with rectosigmoid schistosomiasis had a significantly higher CA-125 level and a larger proportion of these patients were at an early tumor stage (P = 0.003). Various morphological characteristics of schistosomiasis combined with rectosigmoid cancer could be found by colonoscopic examination: 46% were fungating mass polyps, 23% were congestive and ulcerative polyps, 23% were cauliflower-like masses, 8% were annular masses. Only 27% of the patients were diagnosed with rectal carcinoma preoperatively after the biopsy. Computed tomography (CT) scans showed thickened intestinal walls combined with linear and tram-track calcifications in 26 patients. CONCLUSION: Rectosigmoid carcinoma combined with schistosomiasis is associated with higher CA-125 values and early tumor stages. CA-125 and CT scans have a reasonable sensitivity for the accurate diagnosis. SN - 2219-2840 UR - https://www.unboundmedicine.com/medline/citation/26109809/Comparison_of_non_schistosomal_rectosigmoid_cancer_and_schistosomal_rectosigmoid_cancer_ L2 - http://www.wjgnet.com/1007-9327/full/v21/i23/7225.htm DB - PRIME DP - Unbound Medicine ER -