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Quantitative laryngeal electromyography assessment of cricothyroid function in patients with unilateral vocal fold paralysis.
Laryngoscope. 2015 Nov; 125(11):2530-5.L

Abstract

OBJECTIVES/HYPOTHESIS

Determination of superior laryngeal nerve (SLN) involvement in addition to recurrent laryngeal nerve (RLN) paralysis in patients with unilateral vocal fold paralysis (UVFP) relies on traditional, qualitative laryngeal electromyography (LEMG) examination. It is necessary to develop a quantitative measurement that reflects the degree of denervation of the cricothyroid (CT) muscle. The present study aimed to establish a standard quantitative assessment of CT function in patients with UVFP by measuring the turn frequency.

STUDY DESIGN

Case series study performed in an otolaryngology outpatient clinic.

METHODS

Twenty healthy subjects and 103 patients with UVFP were recruited. The main outcome measures for the patients included acoustic analysis using traditional LEMG examination, quantitative LEMG analysis, and acoustic analysis based on fundamental frequency contours.

RESULTS

Acoustic reliability was examined in the healthy subjects, and the peak fundamental frequency in an upward glissando showed good test-retest reliability, especially for the offset fundamental frequency. LEMG indicated that 33 patients had RLN and SLN lesions (RLN+SLN group) and 70 had only RLN lesions (RLN group). When patients produced a standard upward glissando sound, the peak turn frequency reflecting the recruitment of the CT muscle was significantly lower in the RLN+SLN group compared with the RLN group (406±256 vs. 778±238 Hz; P<.001).

CONCLUSIONS

We conclude that quantitative measurement of the interference pattern when voicing a standard upward glissando sound may provide a feasible reflection of the degree of a SLN injury.

LEVEL OF EVIDENCE

4.

Authors+Show Affiliations

Department of Otolaryngology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. School of Medicine, Chang Gung University, Taoyuan, Taiwan.School of Medicine, Chang Gung University, Taoyuan, Taiwan. Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.Department of Otolaryngology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. School of Medicine, Chang Gung University, Taoyuan, Taiwan.Department of Otolaryngology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. School of Medicine, Chang Gung University, Taoyuan, Taiwan.Department of Otolaryngology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. School of Medicine, Chang Gung University, Taoyuan, Taiwan.Department of Otolaryngology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. School of Medicine, Chang Gung University, Taoyuan, Taiwan.School of Medicine, Chang Gung University, Taoyuan, Taiwan. Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26110784

Citation

Fang, Tuan-Jen, et al. "Quantitative Laryngeal Electromyography Assessment of Cricothyroid Function in Patients With Unilateral Vocal Fold Paralysis." The Laryngoscope, vol. 125, no. 11, 2015, pp. 2530-5.
Fang TJ, Pei YC, Hsin LJ, et al. Quantitative laryngeal electromyography assessment of cricothyroid function in patients with unilateral vocal fold paralysis. Laryngoscope. 2015;125(11):2530-5.
Fang, T. J., Pei, Y. C., Hsin, L. J., Lin, W. N., Lee, L. A., Li, H. Y., & Wong, A. M. (2015). Quantitative laryngeal electromyography assessment of cricothyroid function in patients with unilateral vocal fold paralysis. The Laryngoscope, 125(11), 2530-5. https://doi.org/10.1002/lary.25418
Fang TJ, et al. Quantitative Laryngeal Electromyography Assessment of Cricothyroid Function in Patients With Unilateral Vocal Fold Paralysis. Laryngoscope. 2015;125(11):2530-5. PubMed PMID: 26110784.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Quantitative laryngeal electromyography assessment of cricothyroid function in patients with unilateral vocal fold paralysis. AU - Fang,Tuan-Jen, AU - Pei,Yu-Cheng, AU - Hsin,Li-Jen, AU - Lin,Wan-Ni, AU - Lee,Li-Ang, AU - Li,Hsueh-Yu, AU - Wong,Alice M K, Y1 - 2015/06/24/ PY - 2015/05/11/accepted PY - 2015/6/26/entrez PY - 2015/6/26/pubmed PY - 2016/2/9/medline KW - Laryngeal electromyography KW - fundamental frequency KW - recruitment analysis KW - superior laryngeal nerve KW - unilateral vocal fold paralysis SP - 2530 EP - 5 JF - The Laryngoscope JO - Laryngoscope VL - 125 IS - 11 N2 - OBJECTIVES/HYPOTHESIS: Determination of superior laryngeal nerve (SLN) involvement in addition to recurrent laryngeal nerve (RLN) paralysis in patients with unilateral vocal fold paralysis (UVFP) relies on traditional, qualitative laryngeal electromyography (LEMG) examination. It is necessary to develop a quantitative measurement that reflects the degree of denervation of the cricothyroid (CT) muscle. The present study aimed to establish a standard quantitative assessment of CT function in patients with UVFP by measuring the turn frequency. STUDY DESIGN: Case series study performed in an otolaryngology outpatient clinic. METHODS: Twenty healthy subjects and 103 patients with UVFP were recruited. The main outcome measures for the patients included acoustic analysis using traditional LEMG examination, quantitative LEMG analysis, and acoustic analysis based on fundamental frequency contours. RESULTS: Acoustic reliability was examined in the healthy subjects, and the peak fundamental frequency in an upward glissando showed good test-retest reliability, especially for the offset fundamental frequency. LEMG indicated that 33 patients had RLN and SLN lesions (RLN+SLN group) and 70 had only RLN lesions (RLN group). When patients produced a standard upward glissando sound, the peak turn frequency reflecting the recruitment of the CT muscle was significantly lower in the RLN+SLN group compared with the RLN group (406±256 vs. 778±238 Hz; P<.001). CONCLUSIONS: We conclude that quantitative measurement of the interference pattern when voicing a standard upward glissando sound may provide a feasible reflection of the degree of a SLN injury. LEVEL OF EVIDENCE: 4. SN - 1531-4995 UR - https://www.unboundmedicine.com/medline/citation/26110784/Quantitative_laryngeal_electromyography_assessment_of_cricothyroid_function_in_patients_with_unilateral_vocal_fold_paralysis_ L2 - https://doi.org/10.1002/lary.25418 DB - PRIME DP - Unbound Medicine ER -