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Chemical composition and antibacterial activity of essential oil of Nepeta graciliflora Benth. (Lamiaceae).
Nat Prod Res. 2016 Jun; 30(11):1332-4.NP

Abstract

The chemical composition of the essential oil obtained from aerial parts of Nepeta graciliflora was analysed, for the first time, by GC-FID and GC-MS. A total of 27 compounds were identified, constituting over 91.44% of oil composition. The oil was strongly characterised by sesquiterpenes (86.72%), with β-sesquiphellandrene (28.75%), caryophyllene oxide (12.15%), α-bisabolol (8.97%), α-bergamotene (8.51%), β-bisabolene (6.33%) and β-Caryophyllene (5.34%) as the main constituents. The in vitro activity of the essential oil was determined against four micro-organisms in comparison with chloramphenicol by the agar well diffusion and broth dilution method. The oil exhibited good activity against all tested organisms.

Authors+Show Affiliations

a Department of Chemistry , Kumaun University , SSJ Campus, Almora , Uttarakhand 263601 , India.a Department of Chemistry , Kumaun University , SSJ Campus, Almora , Uttarakhand 263601 , India.b Department of Chemistry , MM University , Sadopur, Ambala , Harayana , India.c G.B. Pant Institute of Himalayan Environment & Development , Katarmal, Almora , India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26140331

Citation

Sharma, Pankaj, et al. "Chemical Composition and Antibacterial Activity of Essential Oil of Nepeta Graciliflora Benth. (Lamiaceae)." Natural Product Research, vol. 30, no. 11, 2016, pp. 1332-4.
Sharma P, Shah GC, Sharma R, et al. Chemical composition and antibacterial activity of essential oil of Nepeta graciliflora Benth. (Lamiaceae). Nat Prod Res. 2016;30(11):1332-4.
Sharma, P., Shah, G. C., Sharma, R., & Dhyani, P. (2016). Chemical composition and antibacterial activity of essential oil of Nepeta graciliflora Benth. (Lamiaceae). Natural Product Research, 30(11), 1332-4. https://doi.org/10.1080/14786419.2015.1055489
Sharma P, et al. Chemical Composition and Antibacterial Activity of Essential Oil of Nepeta Graciliflora Benth. (Lamiaceae). Nat Prod Res. 2016;30(11):1332-4. PubMed PMID: 26140331.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and antibacterial activity of essential oil of Nepeta graciliflora Benth. (Lamiaceae). AU - Sharma,Pankaj, AU - Shah,G C, AU - Sharma,Rabia, AU - Dhyani,Praveen, Y1 - 2015/07/03/ PY - 2015/7/4/entrez PY - 2015/7/4/pubmed PY - 2017/5/24/medline KW - Nepeta graciliflora KW - antibacterial activity KW - chemical composition KW - essential oil SP - 1332 EP - 4 JF - Natural product research JO - Nat Prod Res VL - 30 IS - 11 N2 - The chemical composition of the essential oil obtained from aerial parts of Nepeta graciliflora was analysed, for the first time, by GC-FID and GC-MS. A total of 27 compounds were identified, constituting over 91.44% of oil composition. The oil was strongly characterised by sesquiterpenes (86.72%), with β-sesquiphellandrene (28.75%), caryophyllene oxide (12.15%), α-bisabolol (8.97%), α-bergamotene (8.51%), β-bisabolene (6.33%) and β-Caryophyllene (5.34%) as the main constituents. The in vitro activity of the essential oil was determined against four micro-organisms in comparison with chloramphenicol by the agar well diffusion and broth dilution method. The oil exhibited good activity against all tested organisms. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/26140331/Chemical_composition_and_antibacterial_activity_of_essential_oil_of_Nepeta_graciliflora_Benth___Lamiaceae__ L2 - https://www.tandfonline.com/doi/full/10.1080/14786419.2015.1055489 DB - PRIME DP - Unbound Medicine ER -