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Hard calcified intrasellar schwannoma mimicking pituitary adenoma: a case report and review of the literature.
Clin Neurol Neurosurg. 2015 Oct; 137:38-43.CN

Abstract

BACKGROUND

Intrasellar location of schwannoma is extremely rare, although intracranial schwannomas are common in the central nervous system. The aim of the present study is to describe a calcified intrasellar schwannoma case.

MATERIALS AND METHODS

We represent a 45-year-old woman who had suffered from headaches; right side facial pain and visual disturbance which had worsen during the last week prior to admission. Physical examinations were normal except for the bitemporal visual field hemianopia which match with perimetry examination. MRI demonstrated an unusual seemingly calcified mass lesion in the sellar region which was mimicking pituitary macro adenoma.

RESULT

Total resection of the tumor achieved through endoscopic transnasal transsphenoidal approach by extracapsular dissection and pathologic examination of the tumor revealed calcified schwannoma.

CONCLUSION

The differential diagnoses of sellar and suprasellar lesions include pituitary adenomas, craniopharyngiomas, meningiomas, and many others. However, schwannoma is not usually included, because the occurrence of schwannoma in the sellar or suprasellar region is extremely rare. Only few cases of intrasellar schwannomas have been reported in the literature, all of which presented a suprasellar extension similar to that of our case. Fascinating surgical point is managing very firm tumor through transsphenoidal corridor which we handle it by very sharp, debulking and extracapsular removal.

Authors+Show Affiliations

Department of Neurosurgery, Loghman e Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, Loghman e Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: mehrdaada@yahoo.com.Department of Neurosurgery, Firouzgar Hospital, Iran University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, Erfan General Hospital, Tehran, Iran.Department of Neurosurgery, Loghman e Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Neuropathology, Loghman e Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, Loghman e Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

26142086

Citation

Sharifi, Guive, et al. "Hard Calcified Intrasellar Schwannoma Mimicking Pituitary Adenoma: a Case Report and Review of the Literature." Clinical Neurology and Neurosurgery, vol. 137, 2015, pp. 38-43.
Sharifi G, Bakhtevari MH, Alghasi M, et al. Hard calcified intrasellar schwannoma mimicking pituitary adenoma: a case report and review of the literature. Clin Neurol Neurosurg. 2015;137:38-43.
Sharifi, G., Bakhtevari, M. H., Alghasi, M., Saberi, M., Dehghan, M., Bidari, F., & Rezaei, O. (2015). Hard calcified intrasellar schwannoma mimicking pituitary adenoma: a case report and review of the literature. Clinical Neurology and Neurosurgery, 137, 38-43. https://doi.org/10.1016/j.clineuro.2015.06.001
Sharifi G, et al. Hard Calcified Intrasellar Schwannoma Mimicking Pituitary Adenoma: a Case Report and Review of the Literature. Clin Neurol Neurosurg. 2015;137:38-43. PubMed PMID: 26142086.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hard calcified intrasellar schwannoma mimicking pituitary adenoma: a case report and review of the literature. AU - Sharifi,Guive, AU - Bakhtevari,Mehrdad Hosseinzadeh, AU - Alghasi,Mohsen, AU - Saberi,Masood, AU - Dehghan,Mahmood, AU - Bidari,Farahnaz, AU - Rezaei,Omidvar, Y1 - 2015/06/18/ PY - 2015/04/01/received PY - 2015/05/23/revised PY - 2015/06/02/accepted PY - 2015/7/5/entrez PY - 2015/7/5/pubmed PY - 2016/8/31/medline KW - Calcified KW - Pituitary KW - Schwannoma KW - Sellar SP - 38 EP - 43 JF - Clinical neurology and neurosurgery JO - Clin Neurol Neurosurg VL - 137 N2 - BACKGROUND: Intrasellar location of schwannoma is extremely rare, although intracranial schwannomas are common in the central nervous system. The aim of the present study is to describe a calcified intrasellar schwannoma case. MATERIALS AND METHODS: We represent a 45-year-old woman who had suffered from headaches; right side facial pain and visual disturbance which had worsen during the last week prior to admission. Physical examinations were normal except for the bitemporal visual field hemianopia which match with perimetry examination. MRI demonstrated an unusual seemingly calcified mass lesion in the sellar region which was mimicking pituitary macro adenoma. RESULT: Total resection of the tumor achieved through endoscopic transnasal transsphenoidal approach by extracapsular dissection and pathologic examination of the tumor revealed calcified schwannoma. CONCLUSION: The differential diagnoses of sellar and suprasellar lesions include pituitary adenomas, craniopharyngiomas, meningiomas, and many others. However, schwannoma is not usually included, because the occurrence of schwannoma in the sellar or suprasellar region is extremely rare. Only few cases of intrasellar schwannomas have been reported in the literature, all of which presented a suprasellar extension similar to that of our case. Fascinating surgical point is managing very firm tumor through transsphenoidal corridor which we handle it by very sharp, debulking and extracapsular removal. SN - 1872-6968 UR - https://www.unboundmedicine.com/medline/citation/26142086/Hard_calcified_intrasellar_schwannoma_mimicking_pituitary_adenoma:_a_case_report_and_review_of_the_literature_ DB - PRIME DP - Unbound Medicine ER -