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Meta-analysis of female stress urinary incontinence treatments with adjustable single-incision mini-slings and transobturator tension-free vaginal tape surgeries.
BMC Urol. 2015 Jul 07; 15:64.BU

Abstract

BACKGROUND

The study on SIMS and SMUS as a whole by Alyaa Mostafa et al showed that after excluding the TVT-S sling, there is no significant difference in patient-reported cure rate and objective cure rate between these two methods. In this paper, we systematically evaluate the relevant data on SIMS-Ajust and TVT-O/TOT and further confirm their safety and effectiveness, providing reliable clinical evidence.

METHODS

By searching the Medline, Embase, Scopus, and Web of Science databases and the Cochrane Database of Systematic Reviews combined with manual searches, all reports on randomized controlled trials (RCTs) of single-incision mini-sling (SIMS-Ajust) and transobturator tension-free vaginal tape (TVT-O/TOT) surgeries were collected. Using RevMan 5.2 statistical software, the patient-reported cure rate, objective cure rate, operative time, postoperative pain, lower urinary tract injuries, groin pain, postoperative voiding difficulties, de novo urgency and/or worsening of preexisting surgery, vaginal tape erosion, repeated continence surgery, and other related data on both surgical methods were evaluated.

RESULTS

A total of 154 relevant research reports were retrieved, and five randomized controlled trials were included in this study, involving a total of 678 patients. The meta-analysis results show no significant difference in the patient-reported cure rate and objective cure rate between SIMS-Ajust and TVT-O/TOT [RR = 0.95, 95% CI (0.87 to 1.04), P > 0.05; RR = 0.97, 95% CI (0.90-1.05), P > 0.05]. With respect to operation time and groin pain, SIMS-Ajust outperforms TVT-O/TOT [MD = -1.61, 95% CI (-2.48 to 0.74), P < 0.05; RR = 0.30, 95% CI (0.11 to 0.85), P < 0.05]. In terms of postoperative pain, lower urinary tract injuries, postoperative voiding difficulties, de novo urgency and/or worsening of preexisting surgery, vaginal tape erosion, and repetition of continence surgery, there is no significant difference between SIMS-Ajust and TVT-O/TOT [RR = 0.50, 95% CI(0.18-1.43), P > 0.05; RR = 2.82, 95% CI(0.14-57.76), P > 0.05; RR = 0.64, 95% CI(0.28-1.45), P > 0.05; RR = 1.06, 95% CI(0.66-1.71), P > 0.05; RR = 1.04, 95% CI(0.24-4.45), P > 0.05; RR = 1.64, 95% CI(0.41-6.61), P > 0.05].

CONCLUSIONS

SIMS-Ajust is safe and effective in the treatment of female stress urinary incontinence. Compared with TVT-O/TOT surgery, SIMS-Ajust surgery has the same high objective cure rate and patient-reported cure rate and low incidence of perioperative complications, in addition to its short operative time and low incidence of groin pain. Its long-term efficacy needs further observation.

Authors+Show Affiliations

Urology department, Beijing Chaoyang hospital, Capital Medical University, 8 Gongren Tiyuchang NanluChaoyang District, Beijing, 100020, China. syfanbh@126.com.Urology department, Beijing Chaoyang hospital, Capital Medical University, 8 Gongren Tiyuchang NanluChaoyang District, Beijing, 100020, China. syfanbh@163.com.Urology department, Beijing Chaoyang hospital Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China. syfanbh@126.com.Urology department, Beijing Chaoyang hospital Capital Medical University, 8 Gongren Tiyuchang Nanlu,Chaoyang District, Beijing, 100020, China. lyghanhu@sina.com.Urology department, Beijing Chaoyang hospital Capital Medical University, 8 Gongren Tiyuchang Nanlu,Chaoyang District, Beijing, 100020, China. 253532611@qq.com.Urology department, Beijing Chaoyang hospital Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China. wangbiao6176@sina.com.Urology department, Beijing Chaoyang hospital Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China. zxd581@263.net.

Pub Type(s)

Journal Article
Meta-Analysis
Review

Language

eng

PubMed ID

26148987

Citation

Zhang, Peng, et al. "Meta-analysis of Female Stress Urinary Incontinence Treatments With Adjustable Single-incision Mini-slings and Transobturator Tension-free Vaginal Tape Surgeries." BMC Urology, vol. 15, 2015, p. 64.
Zhang P, Fan B, Zhang P, et al. Meta-analysis of female stress urinary incontinence treatments with adjustable single-incision mini-slings and transobturator tension-free vaginal tape surgeries. BMC Urol. 2015;15:64.
Zhang, P., Fan, B., Zhang, P., Han, H., Xu, Y., Wang, B., & Zhang, X. (2015). Meta-analysis of female stress urinary incontinence treatments with adjustable single-incision mini-slings and transobturator tension-free vaginal tape surgeries. BMC Urology, 15, 64. https://doi.org/10.1186/s12894-015-0060-3
Zhang P, et al. Meta-analysis of Female Stress Urinary Incontinence Treatments With Adjustable Single-incision Mini-slings and Transobturator Tension-free Vaginal Tape Surgeries. BMC Urol. 2015 Jul 7;15:64. PubMed PMID: 26148987.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Meta-analysis of female stress urinary incontinence treatments with adjustable single-incision mini-slings and transobturator tension-free vaginal tape surgeries. AU - Zhang,Peng, AU - Fan,Bohan, AU - Zhang,Peng, AU - Han,Hu, AU - Xu,Yue, AU - Wang,Biao, AU - Zhang,Xiaodong, Y1 - 2015/07/07/ PY - 2015/01/31/received PY - 2015/06/22/accepted PY - 2015/7/8/entrez PY - 2015/7/8/pubmed PY - 2016/3/5/medline SP - 64 EP - 64 JF - BMC urology JO - BMC Urol VL - 15 N2 - BACKGROUND: The study on SIMS and SMUS as a whole by Alyaa Mostafa et al showed that after excluding the TVT-S sling, there is no significant difference in patient-reported cure rate and objective cure rate between these two methods. In this paper, we systematically evaluate the relevant data on SIMS-Ajust and TVT-O/TOT and further confirm their safety and effectiveness, providing reliable clinical evidence. METHODS: By searching the Medline, Embase, Scopus, and Web of Science databases and the Cochrane Database of Systematic Reviews combined with manual searches, all reports on randomized controlled trials (RCTs) of single-incision mini-sling (SIMS-Ajust) and transobturator tension-free vaginal tape (TVT-O/TOT) surgeries were collected. Using RevMan 5.2 statistical software, the patient-reported cure rate, objective cure rate, operative time, postoperative pain, lower urinary tract injuries, groin pain, postoperative voiding difficulties, de novo urgency and/or worsening of preexisting surgery, vaginal tape erosion, repeated continence surgery, and other related data on both surgical methods were evaluated. RESULTS: A total of 154 relevant research reports were retrieved, and five randomized controlled trials were included in this study, involving a total of 678 patients. The meta-analysis results show no significant difference in the patient-reported cure rate and objective cure rate between SIMS-Ajust and TVT-O/TOT [RR = 0.95, 95% CI (0.87 to 1.04), P > 0.05; RR = 0.97, 95% CI (0.90-1.05), P > 0.05]. With respect to operation time and groin pain, SIMS-Ajust outperforms TVT-O/TOT [MD = -1.61, 95% CI (-2.48 to 0.74), P < 0.05; RR = 0.30, 95% CI (0.11 to 0.85), P < 0.05]. In terms of postoperative pain, lower urinary tract injuries, postoperative voiding difficulties, de novo urgency and/or worsening of preexisting surgery, vaginal tape erosion, and repetition of continence surgery, there is no significant difference between SIMS-Ajust and TVT-O/TOT [RR = 0.50, 95% CI(0.18-1.43), P > 0.05; RR = 2.82, 95% CI(0.14-57.76), P > 0.05; RR = 0.64, 95% CI(0.28-1.45), P > 0.05; RR = 1.06, 95% CI(0.66-1.71), P > 0.05; RR = 1.04, 95% CI(0.24-4.45), P > 0.05; RR = 1.64, 95% CI(0.41-6.61), P > 0.05]. CONCLUSIONS: SIMS-Ajust is safe and effective in the treatment of female stress urinary incontinence. Compared with TVT-O/TOT surgery, SIMS-Ajust surgery has the same high objective cure rate and patient-reported cure rate and low incidence of perioperative complications, in addition to its short operative time and low incidence of groin pain. Its long-term efficacy needs further observation. SN - 1471-2490 UR - https://www.unboundmedicine.com/medline/citation/26148987/Meta_analysis_of_female_stress_urinary_incontinence_treatments_with_adjustable_single_incision_mini_slings_and_transobturator_tension_free_vaginal_tape_surgeries_ L2 - https://bmcurol.biomedcentral.com/articles/10.1186/s12894-015-0060-3 DB - PRIME DP - Unbound Medicine ER -