Tags

Type your tag names separated by a space and hit enter

Comparative effect of propolis of honey bee and some herbal extracts on Candida albicans.
Chin J Integr Med 2017; 23(3):201-207CJ

Abstract

OBJECTIVES

To determine the effect of propolis on Candida albicans and to compare it with the effects of some other herbal extracts and antibiotics on this pathogenic fungi.

METHODS

The extracts of propolis, Thymus vulgaris, Caryophillium aromaticus, Echinophora platyloba, Allium cepa and Cinnamomum zeylanicum were prepared and the antifungi effects of the extracts were examined on Candida albicans ATCC10231 using disc-diffusion assay and micro-broth dilution. The minimum fungicidal concentration (MFC) and minimum inhibitory concentrations (MIC) as well as inhibition zone were evaluated and the anti fungi effects of herbal extracts were compared with amphotricin B and nystatin at the times of 24, 48 and 72 h. Data analysis was performed using t test.

RESULTS

Obtained results showed that propolis extract with MIC90 and MFC equal to 39 and 65 μg/mL, respectively, possess the highest antifungal activity when compared with other studied extracts. The extracts of Allium cepa and Thymus vulgaris, with MFC of 169 and 137 μg/mL, respectively, showed the lowest effects on the fungi. Also nystatin and amphotricin B yielded better effects on the tested fungi compared with the effects of all studied extracts on Candida albicans.

CONCLUSION

Propolis extract is effective in controlling Candida albicans. However, the issue requires further investigation on samples in animals and performing toxicological examinations.

Authors+Show Affiliations

Young Researchers and Elite Club, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran. shahin.gavanji@khuisf.ac.ir.Young Researchers and Elite Club, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

26149083

Citation

Gavanji, Shahin, and Behrouz Larki. "Comparative Effect of Propolis of Honey Bee and some Herbal Extracts On Candida Albicans." Chinese Journal of Integrative Medicine, vol. 23, no. 3, 2017, pp. 201-207.
Gavanji S, Larki B. Comparative effect of propolis of honey bee and some herbal extracts on Candida albicans. Chin J Integr Med. 2017;23(3):201-207.
Gavanji, S., & Larki, B. (2017). Comparative effect of propolis of honey bee and some herbal extracts on Candida albicans. Chinese Journal of Integrative Medicine, 23(3), pp. 201-207. doi:10.1007/s11655-015-2074-9.
Gavanji S, Larki B. Comparative Effect of Propolis of Honey Bee and some Herbal Extracts On Candida Albicans. Chin J Integr Med. 2017;23(3):201-207. PubMed PMID: 26149083.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative effect of propolis of honey bee and some herbal extracts on Candida albicans. AU - Gavanji,Shahin, AU - Larki,Behrouz, Y1 - 2015/07/07/ PY - 2013/02/28/received PY - 2015/7/8/pubmed PY - 2017/3/16/medline PY - 2015/7/8/entrez KW - Candida albicans KW - antibiotics KW - herbal extract KW - propolis SP - 201 EP - 207 JF - Chinese journal of integrative medicine JO - Chin J Integr Med VL - 23 IS - 3 N2 - OBJECTIVES: To determine the effect of propolis on Candida albicans and to compare it with the effects of some other herbal extracts and antibiotics on this pathogenic fungi. METHODS: The extracts of propolis, Thymus vulgaris, Caryophillium aromaticus, Echinophora platyloba, Allium cepa and Cinnamomum zeylanicum were prepared and the antifungi effects of the extracts were examined on Candida albicans ATCC10231 using disc-diffusion assay and micro-broth dilution. The minimum fungicidal concentration (MFC) and minimum inhibitory concentrations (MIC) as well as inhibition zone were evaluated and the anti fungi effects of herbal extracts were compared with amphotricin B and nystatin at the times of 24, 48 and 72 h. Data analysis was performed using t test. RESULTS: Obtained results showed that propolis extract with MIC90 and MFC equal to 39 and 65 μg/mL, respectively, possess the highest antifungal activity when compared with other studied extracts. The extracts of Allium cepa and Thymus vulgaris, with MFC of 169 and 137 μg/mL, respectively, showed the lowest effects on the fungi. Also nystatin and amphotricin B yielded better effects on the tested fungi compared with the effects of all studied extracts on Candida albicans. CONCLUSION: Propolis extract is effective in controlling Candida albicans. However, the issue requires further investigation on samples in animals and performing toxicological examinations. SN - 1672-0415 UR - https://www.unboundmedicine.com/medline/citation/26149083/Comparative_effect_of_propolis_of_honey_bee_and_some_herbal_extracts_on_Candida_albicans_ L2 - https://dx.doi.org/10.1007/s11655-015-2074-9 DB - PRIME DP - Unbound Medicine ER -