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Sleep-Related Breathing Disorders and the Chiari 1 Malformation.
Chest. 2015 Nov; 148(5):1346-1352.Chest

Abstract

The Chiari 1 malformation is characterized by > 5-mm herniation of the cerebellar tonsils through the foramen magnum. Consequent compression of the brain stem and nearby neuronal structures involved in respiratory control and maintenance of pharyngeal wall muscle tone may result in respiratory changes during sleep. These changes include respiratory failure and arrest, as well as sleep-related breathing disorders (ie, OSA and central sleep apnea). Although data have accrued on the significance of sleep-related breathing disorders in patients with the Chiari 1 malformation, many management questions remain unanswered. This article reviews the available literature on prevalence and management of sleep-related breathing disorders in patients with the Chiari 1 malformation.

Authors+Show Affiliations

Department of Pediatrics, Emory University, Atlanta, GA; Children's Healthcare of Atlanta, Atlanta, GA. Electronic address: Roberta.m.leu@emory.edu.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26158759

Citation

Leu, Roberta M.. "Sleep-Related Breathing Disorders and the Chiari 1 Malformation." Chest, vol. 148, no. 5, 2015, pp. 1346-1352.
Leu RM. Sleep-Related Breathing Disorders and the Chiari 1 Malformation. Chest. 2015;148(5):1346-1352.
Leu, R. M. (2015). Sleep-Related Breathing Disorders and the Chiari 1 Malformation. Chest, 148(5), 1346-1352. https://doi.org/10.1378/chest.14-3090
Leu RM. Sleep-Related Breathing Disorders and the Chiari 1 Malformation. Chest. 2015;148(5):1346-1352. PubMed PMID: 26158759.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sleep-Related Breathing Disorders and the Chiari 1 Malformation. A1 - Leu,Roberta M, PY - 2015/7/10/entrez PY - 2015/7/15/pubmed PY - 2016/2/19/medline SP - 1346 EP - 1352 JF - Chest JO - Chest VL - 148 IS - 5 N2 - The Chiari 1 malformation is characterized by > 5-mm herniation of the cerebellar tonsils through the foramen magnum. Consequent compression of the brain stem and nearby neuronal structures involved in respiratory control and maintenance of pharyngeal wall muscle tone may result in respiratory changes during sleep. These changes include respiratory failure and arrest, as well as sleep-related breathing disorders (ie, OSA and central sleep apnea). Although data have accrued on the significance of sleep-related breathing disorders in patients with the Chiari 1 malformation, many management questions remain unanswered. This article reviews the available literature on prevalence and management of sleep-related breathing disorders in patients with the Chiari 1 malformation. SN - 1931-3543 UR - https://www.unboundmedicine.com/medline/citation/26158759/Sleep_Related_Breathing_Disorders_and_the_Chiari_1_Malformation_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0012-3692(15)50246-8 DB - PRIME DP - Unbound Medicine ER -