[Selected clinical and pathogenetic problems of Binswanger's subcortical arteriosclerotic encephalopathy--analysis of 19 cases].Neurol Neurochir Pol. 1989 Mar-Apr; 23(2):97-104.NN
In 19 patients (14 males, 5 females) the clinical diagnosis of subcortical, arteriosclerotic encephalopathy (s.a.e.) was established on the basis of CT scanning, which showed in subcortical white matter low-attenuation areas and, often, focal ischaemic changes. The age of patients ranged from 46 to 85 years, the duration of illness from 6 months to 12 years. Four patients were normotensive (in 1 of these cases the clinical diagnosis was confirmed neuropathologically). In 2 hypertensive patients the acute development of neurological symptoms was related to considerable fall of systemic RR. On the basis of the CT picture s.a.e. may be diagnosed early, before pronounced neurological and intellectual deficits develop.