Tags

Type your tag names separated by a space and hit enter

Prevalence and Correlates of Chlamydia trachomatis and Neisseria gonorrhoeae by Anatomic Site Among Urban Thai Men Who Have Sex With Men.
Sex Transm Dis. 2015 Aug; 42(8):440-9.ST

Abstract

BACKGROUND

Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection are prevalent among men who have sex with men (MSM) and may infect multiple anatomic sites. We measured site-specific prevalence and correlates of CT and NG infection among Bangkok MSM Cohort Study participants.

METHODS

In April 2006 to November 2010, 1744 men enrolled in the Bangkok MSM Cohort Study. Participants provided historical information and underwent physical examination. Rectal, urethral, and pharyngeal CT and NG screening were performed by nucleic acid amplification and/or culture. Logistic regression was used to identify correlates of site-specific CT, NG, and coinfection.

RESULTS

Among 1743 participants, 19.2% were infected with CT and/or NG. CT, NG, and CT-NG coinfection were detected in 11.6%, 4.6%, and 2.9%, of participants, respectively. Rectal, urethral, and pharyngeal CT infections were detected in 9.5%, 4.5%, and 3.6% of cases. N. gonorrhoeae was present at these sites in 6.1%, 1.8%, and 0.5% of cases. Most infections were asymptomatic (CT: 95.3%, NG: 83.2%). Rectal CT and NG infections were mutually associated (CT: adjusted odds ratio [AOR], 5.4; 95% confidence interval [CI], 3.4-8.7; NG: AOR, 2.4; 95% CI, 1.1-5.2) and independently associated with HIV infection (CT: AOR, 1.6, 95% CI, 1.0-2.4; NG: AOR, 2.0, 95% CI, 1.3-3.1). Numerous behavioral correlates of infection were observed.

CONCLUSIONS

CT and NG infections are highly prevalent among MSM in Bangkok, most frequently affect the rectum, and are most often asymptomatic. Routine screening of asymptomatic MSM for CT and NG infection should include rectal sampling and focus on men with HIV and a history of other sexually transmitted infections.

Authors+Show Affiliations

From the *Thailand Ministry of Public Health-Centers for Disease Control and Prevention Collaboration, Nonthaburi, Bangkok, Thailand; †FHI 360-Asia Pacific Regional Office, Bangkok, Thailand; ‡AVRAM Corporation, Miami, FL; §Thai Bureau of AIDS, TB and STD, Department of Communicable Disease Control, Ministry of Public Health, Bangkok, Thailand; ¶Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA; ∥Thai Red Cross Society AIDS Research Center, Bangkok, Thailand; and **Division of Infectious Diseases, Department of Medicine, Oregon Health and Sciences University, Portland, OR.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

26165436

Citation

Tongtoyai, Jaray, et al. "Prevalence and Correlates of Chlamydia Trachomatis and Neisseria Gonorrhoeae By Anatomic Site Among Urban Thai Men Who Have Sex With Men." Sexually Transmitted Diseases, vol. 42, no. 8, 2015, pp. 440-9.
Tongtoyai J, Todd CS, Chonwattana W, et al. Prevalence and Correlates of Chlamydia trachomatis and Neisseria gonorrhoeae by Anatomic Site Among Urban Thai Men Who Have Sex With Men. Sex Transm Dis. 2015;42(8):440-9.
Tongtoyai, J., Todd, C. S., Chonwattana, W., Pattanasin, S., Chaikummao, S., Varangrat, A., Lokpichart, S., Holtz, T. H., van Griensven, F., & Curlin, M. E. (2015). Prevalence and Correlates of Chlamydia trachomatis and Neisseria gonorrhoeae by Anatomic Site Among Urban Thai Men Who Have Sex With Men. Sexually Transmitted Diseases, 42(8), 440-9. https://doi.org/10.1097/OLQ.0000000000000311
Tongtoyai J, et al. Prevalence and Correlates of Chlamydia Trachomatis and Neisseria Gonorrhoeae By Anatomic Site Among Urban Thai Men Who Have Sex With Men. Sex Transm Dis. 2015;42(8):440-9. PubMed PMID: 26165436.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and Correlates of Chlamydia trachomatis and Neisseria gonorrhoeae by Anatomic Site Among Urban Thai Men Who Have Sex With Men. AU - Tongtoyai,Jaray, AU - Todd,Catherine S, AU - Chonwattana,Wannee, AU - Pattanasin,Sarika, AU - Chaikummao,Supaporn, AU - Varangrat,Anchalee, AU - Lokpichart,Somchai, AU - Holtz,Timothy H, AU - van Griensven,Frits, AU - Curlin,Marcel E, PY - 2015/7/14/entrez PY - 2015/7/15/pubmed PY - 2016/5/18/medline SP - 440 EP - 9 JF - Sexually transmitted diseases JO - Sex Transm Dis VL - 42 IS - 8 N2 - BACKGROUND: Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection are prevalent among men who have sex with men (MSM) and may infect multiple anatomic sites. We measured site-specific prevalence and correlates of CT and NG infection among Bangkok MSM Cohort Study participants. METHODS: In April 2006 to November 2010, 1744 men enrolled in the Bangkok MSM Cohort Study. Participants provided historical information and underwent physical examination. Rectal, urethral, and pharyngeal CT and NG screening were performed by nucleic acid amplification and/or culture. Logistic regression was used to identify correlates of site-specific CT, NG, and coinfection. RESULTS: Among 1743 participants, 19.2% were infected with CT and/or NG. CT, NG, and CT-NG coinfection were detected in 11.6%, 4.6%, and 2.9%, of participants, respectively. Rectal, urethral, and pharyngeal CT infections were detected in 9.5%, 4.5%, and 3.6% of cases. N. gonorrhoeae was present at these sites in 6.1%, 1.8%, and 0.5% of cases. Most infections were asymptomatic (CT: 95.3%, NG: 83.2%). Rectal CT and NG infections were mutually associated (CT: adjusted odds ratio [AOR], 5.4; 95% confidence interval [CI], 3.4-8.7; NG: AOR, 2.4; 95% CI, 1.1-5.2) and independently associated with HIV infection (CT: AOR, 1.6, 95% CI, 1.0-2.4; NG: AOR, 2.0, 95% CI, 1.3-3.1). Numerous behavioral correlates of infection were observed. CONCLUSIONS: CT and NG infections are highly prevalent among MSM in Bangkok, most frequently affect the rectum, and are most often asymptomatic. Routine screening of asymptomatic MSM for CT and NG infection should include rectal sampling and focus on men with HIV and a history of other sexually transmitted infections. SN - 1537-4521 UR - https://www.unboundmedicine.com/medline/citation/26165436/Prevalence_and_Correlates_of_Chlamydia_trachomatis_and_Neisseria_gonorrhoeae_by_Anatomic_Site_Among_Urban_Thai_Men_Who_Have_Sex_With_Men_ L2 - https://doi.org/10.1097/OLQ.0000000000000311 DB - PRIME DP - Unbound Medicine ER -