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Resveratrol: A Focus on Several Neurodegenerative Diseases.
Oxid Med Cell Longev. 2015; 2015:392169.OM

Abstract

Molecules of the plant world are proving their effectiveness in countering, slowing down, and regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene structure has been proven to be a universal panacea, especially for a wide range of neurodegenerative diseases. This paper evaluates (in vivo and in vitro) the various molecular targets of this peculiar polyphenol and its ability to effectively counter several neurodegenerative disorders such as Parkinson's, Alzheimer's, and Huntington's diseases and amyotrophic lateral sclerosis. What emerges is that, in the deep heterogeneity of the pathologies evaluated, resveratrol through a convergence on the protein targets is able to give therapeutic responses in neuronal cells deeply diversified not only in morphological structure but especially in their function performed in the anatomical district to which they belong.

Authors+Show Affiliations

Department of Chemical Sciences, University of Messina, V. le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.Department of Chemical Sciences, University of Messina, V. le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.Department of Chemical Sciences, University of Messina, V. le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.Biochemistry and Clinical Biochemistry Institute, School of Medicine, Catholic University, L. go F. Vito n.1, 00168 Rome, Italy ; C.N.R. Institute of Chemistry of Molecular Recognition, L. go F. Vito n.1, 00168 Rome, Italy.Department of Chemical Sciences, University of Messina, V. le Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26180587

Citation

Tellone, Ester, et al. "Resveratrol: a Focus On Several Neurodegenerative Diseases." Oxidative Medicine and Cellular Longevity, vol. 2015, 2015, p. 392169.
Tellone E, Galtieri A, Russo A, et al. Resveratrol: A Focus on Several Neurodegenerative Diseases. Oxid Med Cell Longev. 2015;2015:392169.
Tellone, E., Galtieri, A., Russo, A., Giardina, B., & Ficarra, S. (2015). Resveratrol: A Focus on Several Neurodegenerative Diseases. Oxidative Medicine and Cellular Longevity, 2015, 392169. https://doi.org/10.1155/2015/392169
Tellone E, et al. Resveratrol: a Focus On Several Neurodegenerative Diseases. Oxid Med Cell Longev. 2015;2015:392169. PubMed PMID: 26180587.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Resveratrol: A Focus on Several Neurodegenerative Diseases. AU - Tellone,Ester, AU - Galtieri,Antonio, AU - Russo,Annamaria, AU - Giardina,Bruno, AU - Ficarra,Silvana, Y1 - 2015/06/09/ PY - 2014/09/26/received PY - 2014/12/19/revised PY - 2014/12/26/accepted PY - 2015/7/17/entrez PY - 2015/7/17/pubmed PY - 2016/4/20/medline SP - 392169 EP - 392169 JF - Oxidative medicine and cellular longevity JO - Oxid Med Cell Longev VL - 2015 N2 - Molecules of the plant world are proving their effectiveness in countering, slowing down, and regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene structure has been proven to be a universal panacea, especially for a wide range of neurodegenerative diseases. This paper evaluates (in vivo and in vitro) the various molecular targets of this peculiar polyphenol and its ability to effectively counter several neurodegenerative disorders such as Parkinson's, Alzheimer's, and Huntington's diseases and amyotrophic lateral sclerosis. What emerges is that, in the deep heterogeneity of the pathologies evaluated, resveratrol through a convergence on the protein targets is able to give therapeutic responses in neuronal cells deeply diversified not only in morphological structure but especially in their function performed in the anatomical district to which they belong. SN - 1942-0994 UR - https://www.unboundmedicine.com/medline/citation/26180587/Resveratrol:_A_Focus_on_Several_Neurodegenerative_Diseases_ L2 - https://dx.doi.org/10.1155/2015/392169 DB - PRIME DP - Unbound Medicine ER -