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Antimicrobial activity of silver and gold in toothpastes: A comparative analysis.
Stomatologija. 2015; 17(1):9-12.S

Abstract

OBJECTIVE

In this study, we compared the antimicrobial activity of identical toothpastes differing only in silver or gold nanoparticles against the activity of one of the common toothpastes containing a chemical active ingredient. We also compared the active concentrations of the toothpastes.

METHODS

For this study, we selected "Royal Denta" toothpastes containing silver and gold particles, and the "Blend-A-Med Complete" toothpaste containing zinc citrate as the active ingredient. We used 8 standard microorganism cultures on the basis of their individual mechanisms of protection. The antimicrobial activity of each studied preparation was evaluated at 9 concentrations.

RESULTS

Most effective against gram-positive bacteria (Staphylococcus aureus and Enterococcus faecalis) was the "Silver Technology" – MIC was 0.004-0.0015 g/mL. Neither "Silver Technology" nor "Orange and Gold Technology" had any effect on Escherichia coli or Proteus mirabilis. Antimicrobial activity against the motile bacterium Proteus mirabilis was observed in "Silver Technology", "Orange and Gold Technology", and "Blend-A-Med Complete" – the MIC was 0.015 g/mL or lower. No antimicrobial activity against Candida albicans fungus at the studied concentrations was observed in the "Orange and Gold Technology". The toothpaste "Blend-A-Med" demonstrated the most effective antimicrobial activity - the MIC of 0.0015 g/mL and 0.015 g/mL inhibited Staphylococcus aureus and Enterococcus faecalis, respectively, and the MIC of 0.15 g/mL inhibited the growth of the bacteria Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and fungus Candida albicans.

CONCLUSIONS

Silver in toothpaste has a greater antimicrobial effect than gold, but its effect is still inferior to that of a chemical antimicrobial agent.

Authors+Show Affiliations

No affiliation info availableNo affiliation info availableUkmergės g. 32-18, Kaunas, Lithuania. kcesaitis@gmail.com.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

26183852

Citation

Junevičius, Jonas, et al. "Antimicrobial Activity of Silver and Gold in Toothpastes: a Comparative Analysis." Stomatologija, vol. 17, no. 1, 2015, pp. 9-12.
Junevičius J, Žilinskas J, Česaitis K, et al. Antimicrobial activity of silver and gold in toothpastes: A comparative analysis. Stomatologija. 2015;17(1):9-12.
Junevičius, J., Žilinskas, J., Česaitis, K., Česaitienė, G., Gleiznys, D., & Maželienė, Ž. (2015). Antimicrobial activity of silver and gold in toothpastes: A comparative analysis. Stomatologija, 17(1), 9-12.
Junevičius J, et al. Antimicrobial Activity of Silver and Gold in Toothpastes: a Comparative Analysis. Stomatologija. 2015;17(1):9-12. PubMed PMID: 26183852.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial activity of silver and gold in toothpastes: A comparative analysis. AU - Junevičius,Jonas, AU - Žilinskas,Juozas, AU - Česaitis,Kęstutis, AU - Česaitienė,Gabrielė, AU - Gleiznys,Darius, AU - Maželienė,Žaneta, PY - 2015/7/18/entrez PY - 2015/7/18/pubmed PY - 2016/11/9/medline SP - 9 EP - 12 JF - Stomatologija JO - Stomatologija VL - 17 IS - 1 N2 - OBJECTIVE: In this study, we compared the antimicrobial activity of identical toothpastes differing only in silver or gold nanoparticles against the activity of one of the common toothpastes containing a chemical active ingredient. We also compared the active concentrations of the toothpastes. METHODS: For this study, we selected "Royal Denta" toothpastes containing silver and gold particles, and the "Blend-A-Med Complete" toothpaste containing zinc citrate as the active ingredient. We used 8 standard microorganism cultures on the basis of their individual mechanisms of protection. The antimicrobial activity of each studied preparation was evaluated at 9 concentrations. RESULTS: Most effective against gram-positive bacteria (Staphylococcus aureus and Enterococcus faecalis) was the "Silver Technology" – MIC was 0.004-0.0015 g/mL. Neither "Silver Technology" nor "Orange and Gold Technology" had any effect on Escherichia coli or Proteus mirabilis. Antimicrobial activity against the motile bacterium Proteus mirabilis was observed in "Silver Technology", "Orange and Gold Technology", and "Blend-A-Med Complete" – the MIC was 0.015 g/mL or lower. No antimicrobial activity against Candida albicans fungus at the studied concentrations was observed in the "Orange and Gold Technology". The toothpaste "Blend-A-Med" demonstrated the most effective antimicrobial activity - the MIC of 0.0015 g/mL and 0.015 g/mL inhibited Staphylococcus aureus and Enterococcus faecalis, respectively, and the MIC of 0.15 g/mL inhibited the growth of the bacteria Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and fungus Candida albicans. CONCLUSIONS: Silver in toothpaste has a greater antimicrobial effect than gold, but its effect is still inferior to that of a chemical antimicrobial agent. SN - 1822-301X UR - https://www.unboundmedicine.com/medline/citation/26183852/Antimicrobial_activity_of_silver_and_gold_in_toothpastes:_A_comparative_analysis_ L2 - http://sbdmj.lsmuni.lt/151/151-02.pdf DB - PRIME DP - Unbound Medicine ER -