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Large two-centre study into the prevalence of Mycoplasma genitalium and Trichomonas vaginalis in the Netherlands.
Int J STD AIDS 2016; 27(10):856-60IJ

Abstract

Mycoplasma genitalium and Trichomonas vaginalis are common sexually transmitted infections (STIs). In the Netherlands, testing for M. genitalium and T. vaginalis is not recommended for first-line STI screening. Recent reports about the increasing antimicrobial resistance in M. genitalium raise concern about the adequacy of current empirical treatment regimens. It is necessary to have insight in the prevalence of M. genitalium and T. vaginalis in order to evaluate current first-line STI screening and treatment protocols. During a five-month period, samples sent to two large medical microbiology diagnostic centres in the Netherlands for STI screening (Chlamydia trachomatis and Neisseria gonorrhoeae) were retrospectively tested for the prevalence of M. genitalium and T. vaginalis using the Diagenode S-DiaMGTV kit. A total of 1569 samples from 1188 unique patients (55.4% female) were tested. M. genitalium was the second most prevalent STI detected (4.5% of the patients), after C. trachomatis (8.3%). T. vaginalis was detected in 1.4% of the patients, comparable to the prevalence of N. gonorrhoeae (1.3%). Dual infections were only detected in a small number of patients (1.0%). Incorporation of M. genitalium into routine STI screening should be considered, because of its relatively high prevalence, the consequences of its detection for antibiotic treatment and because of the availability of easy-to-use molecular diagnostic tests. For T. vaginalis, routine screening may be considered, depending on local prevalence and (sub)population.

Authors+Show Affiliations

Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands arjan.dejong@radboudumc.nl.Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.PAMM, Laboratory of Medical Microbiology, Veldhoven, the Netherlands.Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.PAMM, Laboratory of Medical Microbiology, Veldhoven, the Netherlands.Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.PAMM, Laboratory of Medical Microbiology, Veldhoven, the Netherlands.

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

26199286

Citation

de Jong, A S., et al. "Large Two-centre Study Into the Prevalence of Mycoplasma Genitalium and Trichomonas Vaginalis in the Netherlands." International Journal of STD & AIDS, vol. 27, no. 10, 2016, pp. 856-60.
de Jong AS, Rahamat-Langendoen JC, van Alphen P, et al. Large two-centre study into the prevalence of Mycoplasma genitalium and Trichomonas vaginalis in the Netherlands. Int J STD AIDS. 2016;27(10):856-60.
de Jong, A. S., Rahamat-Langendoen, J. C., van Alphen, P., Hilt, N., van Herk, C., Pont, S., ... van de Bovenkamp, J. (2016). Large two-centre study into the prevalence of Mycoplasma genitalium and Trichomonas vaginalis in the Netherlands. International Journal of STD & AIDS, 27(10), pp. 856-60. doi:10.1177/0956462415596496.
de Jong AS, et al. Large Two-centre Study Into the Prevalence of Mycoplasma Genitalium and Trichomonas Vaginalis in the Netherlands. Int J STD AIDS. 2016;27(10):856-60. PubMed PMID: 26199286.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Large two-centre study into the prevalence of Mycoplasma genitalium and Trichomonas vaginalis in the Netherlands. AU - de Jong,A S, AU - Rahamat-Langendoen,J C, AU - van Alphen,Ptw, AU - Hilt,N, AU - van Herk,Cmc, AU - Pont,Sbeh, AU - Melchers,Wjg, AU - van de Bovenkamp,Jhb, Y1 - 2015/07/20/ PY - 2015/03/17/received PY - 2015/06/22/accepted PY - 2015/7/23/entrez PY - 2015/7/23/pubmed PY - 2017/7/1/medline KW - Mycoplasma genitalium KW - Protozoal disease KW - Screening KW - Trichomoniasis (Trichomonas vaginalis) KW - sexually transmitted infection SP - 856 EP - 60 JF - International journal of STD & AIDS JO - Int J STD AIDS VL - 27 IS - 10 N2 - Mycoplasma genitalium and Trichomonas vaginalis are common sexually transmitted infections (STIs). In the Netherlands, testing for M. genitalium and T. vaginalis is not recommended for first-line STI screening. Recent reports about the increasing antimicrobial resistance in M. genitalium raise concern about the adequacy of current empirical treatment regimens. It is necessary to have insight in the prevalence of M. genitalium and T. vaginalis in order to evaluate current first-line STI screening and treatment protocols. During a five-month period, samples sent to two large medical microbiology diagnostic centres in the Netherlands for STI screening (Chlamydia trachomatis and Neisseria gonorrhoeae) were retrospectively tested for the prevalence of M. genitalium and T. vaginalis using the Diagenode S-DiaMGTV kit. A total of 1569 samples from 1188 unique patients (55.4% female) were tested. M. genitalium was the second most prevalent STI detected (4.5% of the patients), after C. trachomatis (8.3%). T. vaginalis was detected in 1.4% of the patients, comparable to the prevalence of N. gonorrhoeae (1.3%). Dual infections were only detected in a small number of patients (1.0%). Incorporation of M. genitalium into routine STI screening should be considered, because of its relatively high prevalence, the consequences of its detection for antibiotic treatment and because of the availability of easy-to-use molecular diagnostic tests. For T. vaginalis, routine screening may be considered, depending on local prevalence and (sub)population. SN - 1758-1052 UR - https://www.unboundmedicine.com/medline/citation/26199286/Large_two_centre_study_into_the_prevalence_of_Mycoplasma_genitalium_and_Trichomonas_vaginalis_in_the_Netherlands_ L2 - http://journals.sagepub.com/doi/full/10.1177/0956462415596496?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -