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Vitamin D supplements in chronic kidney disease.
Ren Fail. 2015 Jul; 37(6):917-24.RF

Abstract

Chronic kidney disease (CKD) is a significant public health problem and Vitamin D deficiency is prevalent in CKD and might be associated with calcium and phosphate metabolism, cardiovascular disease, infections as well as the progress of kidney dysfunction. Emerging evidence implies that Vitamin D supplements may be of benefit to CKD. Based on existing laboratory and clinical evidence, this review intends to discuss the effectiveness of Vitamin D supplements and controversy in clinical practice. The effect of Vitamin D in CKD patients is summarized in detail from CKD-mineral bone disease, the progression of renal function, cardiovascular events and immune system. Considerable disputes exist for the Vitamin D supplements in CKD, and a growing amount of experimental evidence and some clinical evidence are now gathering from in vitro, animal and epidemiological studies.

Authors+Show Affiliations

a Department of Nephrology , Shanghai Jiao Tong University Affiliated First People's Hospital , Shanghai , P.R. China and.a Department of Nephrology , Shanghai Jiao Tong University Affiliated First People's Hospital , Shanghai , P.R. China and. b Division of Nephrology and Clinical Immunology , University Hospital , RWTH Aachen , Aachen , Germany.a Department of Nephrology , Shanghai Jiao Tong University Affiliated First People's Hospital , Shanghai , P.R. China and.a Department of Nephrology , Shanghai Jiao Tong University Affiliated First People's Hospital , Shanghai , P.R. China and.a Department of Nephrology , Shanghai Jiao Tong University Affiliated First People's Hospital , Shanghai , P.R. China and.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26211501

Citation

Zhu, Nan, et al. "Vitamin D Supplements in Chronic Kidney Disease." Renal Failure, vol. 37, no. 6, 2015, pp. 917-24.
Zhu N, Wang J, Gu L, et al. Vitamin D supplements in chronic kidney disease. Ren Fail. 2015;37(6):917-24.
Zhu, N., Wang, J., Gu, L., Wang, L., & Yuan, W. (2015). Vitamin D supplements in chronic kidney disease. Renal Failure, 37(6), 917-24. https://doi.org/10.3109/0886022X.2015.1043920
Zhu N, et al. Vitamin D Supplements in Chronic Kidney Disease. Ren Fail. 2015;37(6):917-24. PubMed PMID: 26211501.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vitamin D supplements in chronic kidney disease. AU - Zhu,Nan, AU - Wang,Jialin, AU - Gu,Lijie, AU - Wang,Ling, AU - Yuan,Weijie, Y1 - 2015/07/27/ PY - 2015/7/28/entrez PY - 2015/7/28/pubmed PY - 2016/6/11/medline KW - CKD KW - Vitamin D KW - Vitamin D analogs KW - Vitamin D deficiency KW - Vitamin D supplements SP - 917 EP - 24 JF - Renal failure JO - Ren Fail VL - 37 IS - 6 N2 - Chronic kidney disease (CKD) is a significant public health problem and Vitamin D deficiency is prevalent in CKD and might be associated with calcium and phosphate metabolism, cardiovascular disease, infections as well as the progress of kidney dysfunction. Emerging evidence implies that Vitamin D supplements may be of benefit to CKD. Based on existing laboratory and clinical evidence, this review intends to discuss the effectiveness of Vitamin D supplements and controversy in clinical practice. The effect of Vitamin D in CKD patients is summarized in detail from CKD-mineral bone disease, the progression of renal function, cardiovascular events and immune system. Considerable disputes exist for the Vitamin D supplements in CKD, and a growing amount of experimental evidence and some clinical evidence are now gathering from in vitro, animal and epidemiological studies. SN - 1525-6049 UR - https://www.unboundmedicine.com/medline/citation/26211501/Vitamin_D_supplements_in_chronic_kidney_disease_ L2 - https://www.tandfonline.com/doi/full/10.3109/0886022X.2015.1043920 DB - PRIME DP - Unbound Medicine ER -