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Stability of anthocyanins- and anthocyanidins-enriched extracts, and formulations of fruit pulp of Eugenia jambolana ('jamun').
Food Chem. 2016 Jan 01; 190:808-817.FC

Abstract

The fruit pulp of Eugenia jambolana (jamun) is a rich source of anthocyanins (ACs). The purpose of the present study was to assess the effect of various physical and chemical factors on the stability of ACs and anthocyanidins (ACdn) in the crude, anthocyanins-enriched extract (ACs-EEX), anthocyanins-enriched sephadex extract (ACs-EES) and anthocyanidins-enriched extract (ACdn-EEX). ACs and ACdn contents were analyzed using a stability indicating HPLC analytical method. The ACs content reduced to 86.4% (crude extract), 60.9% (ACs-EEX), 36.0% (ACs-EES), 64.8% (ACs-EEX tablet), and 71.7% (ACs-EEX capsules) after 1 year at 5 °C. The ACdn content reduced to 83.1% (ACdn-EEX), 90.1% (ACdn-EEX tablet) and 93.8% (ACdn-EEX capsules) after 1 year at 5 °C. ACs and ACdn showed lesser degradation at low pH and higher degradation at high H2O2 concentration. The thermal degradation products of ACs were identified and quantified.

Authors+Show Affiliations

Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Punjab 160062, India.James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202, USA.Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Punjab 160062, India.Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Punjab 160062, India.Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Punjab 160062, India. Electronic address: ipsingh@niper.ac.in.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26213042

Citation

Sharma, Ram Jee, et al. "Stability of Anthocyanins- and Anthocyanidins-enriched Extracts, and Formulations of Fruit Pulp of Eugenia Jambolana ('jamun')." Food Chemistry, vol. 190, 2016, pp. 808-817.
Sharma RJ, Gupta RC, Singh S, et al. Stability of anthocyanins- and anthocyanidins-enriched extracts, and formulations of fruit pulp of Eugenia jambolana ('jamun'). Food Chem. 2016;190:808-817.
Sharma, R. J., Gupta, R. C., Singh, S., Bansal, A. K., & Singh, I. P. (2016). Stability of anthocyanins- and anthocyanidins-enriched extracts, and formulations of fruit pulp of Eugenia jambolana ('jamun'). Food Chemistry, 190, 808-817. https://doi.org/10.1016/j.foodchem.2015.06.029
Sharma RJ, et al. Stability of Anthocyanins- and Anthocyanidins-enriched Extracts, and Formulations of Fruit Pulp of Eugenia Jambolana ('jamun'). Food Chem. 2016 Jan 1;190:808-817. PubMed PMID: 26213042.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Stability of anthocyanins- and anthocyanidins-enriched extracts, and formulations of fruit pulp of Eugenia jambolana ('jamun'). AU - Sharma,Ram Jee, AU - Gupta,Ramesh C, AU - Singh,Saranjit, AU - Bansal,Arvind Kumar, AU - Singh,Inder Pal, Y1 - 2015/06/11/ PY - 2015/01/21/received PY - 2015/06/09/revised PY - 2015/06/10/accepted PY - 2015/7/28/entrez PY - 2015/7/28/pubmed PY - 2016/2/26/medline KW - Anthocyanidins KW - Anthocyanins KW - Degradation products KW - Eugenia jambolana KW - HPLC-PDA KW - Stability study SP - 808 EP - 817 JF - Food chemistry JO - Food Chem VL - 190 N2 - The fruit pulp of Eugenia jambolana (jamun) is a rich source of anthocyanins (ACs). The purpose of the present study was to assess the effect of various physical and chemical factors on the stability of ACs and anthocyanidins (ACdn) in the crude, anthocyanins-enriched extract (ACs-EEX), anthocyanins-enriched sephadex extract (ACs-EES) and anthocyanidins-enriched extract (ACdn-EEX). ACs and ACdn contents were analyzed using a stability indicating HPLC analytical method. The ACs content reduced to 86.4% (crude extract), 60.9% (ACs-EEX), 36.0% (ACs-EES), 64.8% (ACs-EEX tablet), and 71.7% (ACs-EEX capsules) after 1 year at 5 °C. The ACdn content reduced to 83.1% (ACdn-EEX), 90.1% (ACdn-EEX tablet) and 93.8% (ACdn-EEX capsules) after 1 year at 5 °C. ACs and ACdn showed lesser degradation at low pH and higher degradation at high H2O2 concentration. The thermal degradation products of ACs were identified and quantified. SN - 1873-7072 UR - https://www.unboundmedicine.com/medline/citation/26213042/Stability_of_anthocyanins__and_anthocyanidins_enriched_extracts_and_formulations_of_fruit_pulp_of_Eugenia_jambolana__'jamun'__ DB - PRIME DP - Unbound Medicine ER -