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Patterns of health-related quality of life and associated factors in Chinese patients undergoing haemodialysis.
Health Qual Life Outcomes. 2015 Jul 29; 13:108.HQ

Abstract

BACKGROUND

Haemodialysis (HD) is a life-saving but burdensome therapy for patients with end-stage renal disease (ESRD) which can have a detrimental impact on patients' quality of life and outcomes. There is currently little data on the health related quality of life (HRQOL) of Chinese ESRD patients undergoing HD and this study sought to examine the patterns of HRQOL and its associated factors within this population, as well as in comparison with the general local population.

METHODS

A cross-sectional study of 244 ESRD patients receiving HD in the hospital and in the community in Hong Kong was conducted using the Short Form-12 Health Survey version 2 (SF-12v2). All study subjects were one-to-one matched with subjects in a Hong Kong general population database by sex and exact age. Independent t-tests were performed to compare the mean SF-12v2 scores between HD patients and the general population, followed by one-way analysis of variance with post hoc Tukey's HSD tests to compare community-based haemodialysis, hospital-based haemodialysis and the general population. Multiple linear regressions were used to identify the factors (socio-demographic, clinical characteristics and comorbidities) associated with the HRQOL scores of ESRD patients receiving HD.

RESULTS

The SF-12v2 Physical Functioning, Role Physical, Bodily Pain, General Health and Physical Component Summary scores of HD patients were significantly lower than the age-sex adjusted general population. However, the SF-12v2 Mental Health and Mental Component Summary scores of HD patients were significantly higher than the corresponding general population. Poorer HRQOL was associated with being female, smoking, unemployment and hospital-based haemodialysis.

CONCLUSIONS

HD patients had substantially poorer physical HRQOL but better mental HRQOL than the age-sex adjusted general population. Patients receiving HD in the community setting had better HRQOL. Reasons for these observations will need to be further investigated. Those patients who are female, smokers and unemployed may warrant more attention as their poorer HRQOL may be associated with poorer outcomes.

Authors+Show Affiliations

Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong. yfwan@hku.hk.Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong. juliechen@hku.hk. Institute of Medical and Health Sciences Education, The University of Hong Kong, 2/F William MW Mong Block, 21 Sassoon Road, Pokfulam, Hong Kong. juliechen@hku.hk.School of Nursing, The University of Hong Kong, 4/F William MW Mong Block, 21 Sassoon Road, Pokfulam, Hong Kong. h0714919@connect.hku.hk.Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong. carlosho@hku.hk.Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong. kcchanae@hku.hk.Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong. khychan4@hku.hk.Department of Family Medicine and Primary Care, The University of Hong Kong, 3/F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong. clklam@hku.hk.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26215978

Citation

Wan, Eric Y F., et al. "Patterns of Health-related Quality of Life and Associated Factors in Chinese Patients Undergoing Haemodialysis." Health and Quality of Life Outcomes, vol. 13, 2015, p. 108.
Wan EY, Chen JY, Choi EP, et al. Patterns of health-related quality of life and associated factors in Chinese patients undergoing haemodialysis. Health Qual Life Outcomes. 2015;13:108.
Wan, E. Y., Chen, J. Y., Choi, E. P., Wong, C. K., Chan, A. K., Chan, K. H., & Lam, C. L. (2015). Patterns of health-related quality of life and associated factors in Chinese patients undergoing haemodialysis. Health and Quality of Life Outcomes, 13, 108. https://doi.org/10.1186/s12955-015-0308-3
Wan EY, et al. Patterns of Health-related Quality of Life and Associated Factors in Chinese Patients Undergoing Haemodialysis. Health Qual Life Outcomes. 2015 Jul 29;13:108. PubMed PMID: 26215978.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Patterns of health-related quality of life and associated factors in Chinese patients undergoing haemodialysis. AU - Wan,Eric Y F, AU - Chen,Julie Y, AU - Choi,Edmond P H, AU - Wong,Carlos K H, AU - Chan,Anca K C, AU - Chan,Karina H Y, AU - Lam,Cindy L K, Y1 - 2015/07/29/ PY - 2015/04/18/received PY - 2015/07/17/accepted PY - 2015/7/29/entrez PY - 2015/7/29/pubmed PY - 2016/2/16/medline SP - 108 EP - 108 JF - Health and quality of life outcomes JO - Health Qual Life Outcomes VL - 13 N2 - BACKGROUND: Haemodialysis (HD) is a life-saving but burdensome therapy for patients with end-stage renal disease (ESRD) which can have a detrimental impact on patients' quality of life and outcomes. There is currently little data on the health related quality of life (HRQOL) of Chinese ESRD patients undergoing HD and this study sought to examine the patterns of HRQOL and its associated factors within this population, as well as in comparison with the general local population. METHODS: A cross-sectional study of 244 ESRD patients receiving HD in the hospital and in the community in Hong Kong was conducted using the Short Form-12 Health Survey version 2 (SF-12v2). All study subjects were one-to-one matched with subjects in a Hong Kong general population database by sex and exact age. Independent t-tests were performed to compare the mean SF-12v2 scores between HD patients and the general population, followed by one-way analysis of variance with post hoc Tukey's HSD tests to compare community-based haemodialysis, hospital-based haemodialysis and the general population. Multiple linear regressions were used to identify the factors (socio-demographic, clinical characteristics and comorbidities) associated with the HRQOL scores of ESRD patients receiving HD. RESULTS: The SF-12v2 Physical Functioning, Role Physical, Bodily Pain, General Health and Physical Component Summary scores of HD patients were significantly lower than the age-sex adjusted general population. However, the SF-12v2 Mental Health and Mental Component Summary scores of HD patients were significantly higher than the corresponding general population. Poorer HRQOL was associated with being female, smoking, unemployment and hospital-based haemodialysis. CONCLUSIONS: HD patients had substantially poorer physical HRQOL but better mental HRQOL than the age-sex adjusted general population. Patients receiving HD in the community setting had better HRQOL. Reasons for these observations will need to be further investigated. Those patients who are female, smokers and unemployed may warrant more attention as their poorer HRQOL may be associated with poorer outcomes. SN - 1477-7525 UR - https://www.unboundmedicine.com/medline/citation/26215978/Patterns_of_health_related_quality_of_life_and_associated_factors_in_Chinese_patients_undergoing_haemodialysis_ L2 - https://hqlo.biomedcentral.com/articles/10.1186/s12955-015-0308-3 DB - PRIME DP - Unbound Medicine ER -