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Salivary and serum antibodies to gliadin in the diagnosis of celiac disease.
J Oral Pathol Med. 1989 Dec; 18(10):578-81.JO

Abstract

Salivary IgA and serum IgA and IgG antibodies to crude gliadin and alpha-gliadin were measured in adult patients with untreated celiac disease, ulcerative colitis, Crohn's disease and normal controls. Antibody levels in saliva and serum in untreated celiac disease were significantly higher than in other groups. Alpha-gliadin antibodies appeared to be a better discriminator for serum but not for saliva. The assay of salivary IgA antibodies to gliadin offers a non-invasive test which would be particularly useful in the investigation of celiac disease and for monitoring compliance with a gluten-free diet.

Authors+Show Affiliations

Department of Oral Surgery, Medicine and Pathology, University of Wales College of Medicine, Heath Park, Cardiff, England.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2621654

Citation

al-Bayaty, H F., et al. "Salivary and Serum Antibodies to Gliadin in the Diagnosis of Celiac Disease." Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, vol. 18, no. 10, 1989, pp. 578-81.
al-Bayaty HF, Aldred MJ, Walker DM, et al. Salivary and serum antibodies to gliadin in the diagnosis of celiac disease. J Oral Pathol Med. 1989;18(10):578-81.
al-Bayaty, H. F., Aldred, M. J., Walker, D. M., Newcombe, R. G., Swift, G., Smith, P. M., & Ciclitira, P. J. (1989). Salivary and serum antibodies to gliadin in the diagnosis of celiac disease. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 18(10), 578-81.
al-Bayaty HF, et al. Salivary and Serum Antibodies to Gliadin in the Diagnosis of Celiac Disease. J Oral Pathol Med. 1989;18(10):578-81. PubMed PMID: 2621654.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Salivary and serum antibodies to gliadin in the diagnosis of celiac disease. AU - al-Bayaty,H F, AU - Aldred,M J, AU - Walker,D M, AU - Newcombe,R G, AU - Swift,G, AU - Smith,P M, AU - Ciclitira,P J, PY - 1989/12/1/pubmed PY - 1989/12/1/medline PY - 1989/12/1/entrez SP - 578 EP - 81 JF - Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology JO - J Oral Pathol Med VL - 18 IS - 10 N2 - Salivary IgA and serum IgA and IgG antibodies to crude gliadin and alpha-gliadin were measured in adult patients with untreated celiac disease, ulcerative colitis, Crohn's disease and normal controls. Antibody levels in saliva and serum in untreated celiac disease were significantly higher than in other groups. Alpha-gliadin antibodies appeared to be a better discriminator for serum but not for saliva. The assay of salivary IgA antibodies to gliadin offers a non-invasive test which would be particularly useful in the investigation of celiac disease and for monitoring compliance with a gluten-free diet. SN - 0904-2512 UR - https://www.unboundmedicine.com/medline/citation/2621654/Salivary_and_serum_antibodies_to_gliadin_in_the_diagnosis_of_celiac_disease_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0904-2512&date=1989&volume=18&issue=10&spage=578 DB - PRIME DP - Unbound Medicine ER -