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Effects of Transcutaneous Electrical Acupoint Stimulation on Patients with Stable Chronic Obstructive Pulmonary Disease: A Prospective, Single-Blind, Randomized, Placebo-Controlled Study.
J Altern Complement Med. 2015 Oct; 21(10):610-6.JA

Abstract

OBJECTIVES

To evaluate the clinical effect of transcutaneous electrical nerve stimulation over acupoints (acu-TENS) on patients with stable chronic obstructive pulmonary disease (COPD).

DESIGN

Prospective, single-blind, randomized, placebo-controlled study. Settings/Locations: Outpatient center of West China Hospital, Sichuan University.

PATIENTS

Fifty patients with stable COPD enrolled in the study.

INTERVENTIONS

Patients were randomly assigned to one of two groups: the acu-TENS group (n=25), who underwent acu-TENS over acupoints of bilateral EX-B-1(Dingchuan), BL-13 (Feishu), BL-23 (Shenshu), ST-36 (Zusanli), and the placebo acu-TENS control group (n=25), who had the same electrode placement but no electrical output. Treatments were performed for 40-minute sessions every 2 days for 4 weeks.

OUTCOME MEASURES

Lung function (forced expiratory volume in 1 second, percentage predicted (FEV(1)% predicted); forced vital capacity, percentage predicted (FVC% predicted), 6-minute walk distance (6MWD) and oxygen saturation (SpO(2)), COPD assessment test (CAT), and Dyspnea Visual Analogue Scale (DVAS) were assessed before and after the intervention.

RESULTS

Compared to control group, FEV(1)% predicted was improved and CAT score was decreased significantly in the acu-TENS group after treatment (p<0.05). The DVAS score decreased significantly in the acu-TENS group (p=0.039), with a slight but insignificant improve in 6MWD, SpO(2), and FVC% predicted after treatment.

CONCLUSIONS

Acu-TENS over acupoints of bilateral EX-B-1 (Dingchuan), BL-13 (Feishu), BL-23 (Shenshu), and ST-36 (Zusanli) improved FEV(1)% predicted and reduced DVAS and CAT scores on patients with stable COPD. This may be a novel treatment strategy in COPD.

Authors+Show Affiliations

1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China .1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China .2 College of Acupuncture and Tuina, Traditional Chinese Medicine of Chengdu University , Chengdu, Sichuan, China .1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China .1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China .1 Department of Integrated Medicine, West China Hospital of Sichuan University , Chendu, Sichuan, China .

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26218785

Citation

Liu, Xuemei, et al. "Effects of Transcutaneous Electrical Acupoint Stimulation On Patients With Stable Chronic Obstructive Pulmonary Disease: a Prospective, Single-Blind, Randomized, Placebo-Controlled Study." Journal of Alternative and Complementary Medicine (New York, N.Y.), vol. 21, no. 10, 2015, pp. 610-6.
Liu X, Fan T, Lan Y, et al. Effects of Transcutaneous Electrical Acupoint Stimulation on Patients with Stable Chronic Obstructive Pulmonary Disease: A Prospective, Single-Blind, Randomized, Placebo-Controlled Study. J Altern Complement Med. 2015;21(10):610-6.
Liu, X., Fan, T., Lan, Y., Dong, S., Fu, J., & Mao, B. (2015). Effects of Transcutaneous Electrical Acupoint Stimulation on Patients with Stable Chronic Obstructive Pulmonary Disease: A Prospective, Single-Blind, Randomized, Placebo-Controlled Study. Journal of Alternative and Complementary Medicine (New York, N.Y.), 21(10), 610-6. https://doi.org/10.1089/acm.2014.0284
Liu X, et al. Effects of Transcutaneous Electrical Acupoint Stimulation On Patients With Stable Chronic Obstructive Pulmonary Disease: a Prospective, Single-Blind, Randomized, Placebo-Controlled Study. J Altern Complement Med. 2015;21(10):610-6. PubMed PMID: 26218785.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of Transcutaneous Electrical Acupoint Stimulation on Patients with Stable Chronic Obstructive Pulmonary Disease: A Prospective, Single-Blind, Randomized, Placebo-Controlled Study. AU - Liu,Xuemei, AU - Fan,Tao, AU - Lan,Ying, AU - Dong,Shoujing, AU - Fu,Juanjuan, AU - Mao,Bing, Y1 - 2015/07/28/ PY - 2015/7/29/entrez PY - 2015/7/29/pubmed PY - 2016/7/20/medline SP - 610 EP - 6 JF - Journal of alternative and complementary medicine (New York, N.Y.) JO - J Altern Complement Med VL - 21 IS - 10 N2 - OBJECTIVES: To evaluate the clinical effect of transcutaneous electrical nerve stimulation over acupoints (acu-TENS) on patients with stable chronic obstructive pulmonary disease (COPD). DESIGN: Prospective, single-blind, randomized, placebo-controlled study. Settings/Locations: Outpatient center of West China Hospital, Sichuan University. PATIENTS: Fifty patients with stable COPD enrolled in the study. INTERVENTIONS: Patients were randomly assigned to one of two groups: the acu-TENS group (n=25), who underwent acu-TENS over acupoints of bilateral EX-B-1(Dingchuan), BL-13 (Feishu), BL-23 (Shenshu), ST-36 (Zusanli), and the placebo acu-TENS control group (n=25), who had the same electrode placement but no electrical output. Treatments were performed for 40-minute sessions every 2 days for 4 weeks. OUTCOME MEASURES: Lung function (forced expiratory volume in 1 second, percentage predicted (FEV(1)% predicted); forced vital capacity, percentage predicted (FVC% predicted), 6-minute walk distance (6MWD) and oxygen saturation (SpO(2)), COPD assessment test (CAT), and Dyspnea Visual Analogue Scale (DVAS) were assessed before and after the intervention. RESULTS: Compared to control group, FEV(1)% predicted was improved and CAT score was decreased significantly in the acu-TENS group after treatment (p<0.05). The DVAS score decreased significantly in the acu-TENS group (p=0.039), with a slight but insignificant improve in 6MWD, SpO(2), and FVC% predicted after treatment. CONCLUSIONS: Acu-TENS over acupoints of bilateral EX-B-1 (Dingchuan), BL-13 (Feishu), BL-23 (Shenshu), and ST-36 (Zusanli) improved FEV(1)% predicted and reduced DVAS and CAT scores on patients with stable COPD. This may be a novel treatment strategy in COPD. SN - 1557-7708 UR - https://www.unboundmedicine.com/medline/citation/26218785/Effects_of_Transcutaneous_Electrical_Acupoint_Stimulation_on_Patients_with_Stable_Chronic_Obstructive_Pulmonary_Disease:_A_Prospective_Single_Blind_Randomized_Placebo_Controlled_Study_ L2 - https://www.liebertpub.com/doi/10.1089/acm.2014.0284?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -