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Epidemic yellow fever caused by an incompetent mosquito vector.
Trop Med Parasitol. 1989 Dec; 40(4):396-9.TM

Abstract

Arbovirus epidemics in a geographic region are believed to depend on the presence of susceptible or "competent" arthropod vectors. We demonstrate that an urban, Aedes aegypti-borne, epidemic of yellow fever occurred in 1987 although the mosquito vector was relatively resistant to infection and transmitted the virus inefficiently. Twenty-six percent of the experimental mosquitoes from the epidemic area that ingested yellow fever virus became infected and only 7% of these transmitted the virus. In contrast, 80% of an exotic susceptible strain of Ae. aegypti became infected and 43% were able to transmit. We also show that no other potential vectors were active during the epidemic and that the local Ae. aegypti were present in extremely large numbers. These results document, for the first time, that, in the presence of high population density an incompetent mosquito vector can initiate and maintain virus transmission resulting in an epidemic.

Authors+Show Affiliations

Division of Vector-Borne Viral Diseases, Centers for Disease Control, U.S. Department of Health and Human Services, Fort Collins, Colorado.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2623418

Citation

Miller, B R., et al. "Epidemic Yellow Fever Caused By an Incompetent Mosquito Vector." Tropical Medicine and Parasitology : Official Organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft Fur Technische Zusammenarbeit (GTZ), vol. 40, no. 4, 1989, pp. 396-9.
Miller BR, Monath TP, Tabachnick WJ, et al. Epidemic yellow fever caused by an incompetent mosquito vector. Trop Med Parasitol. 1989;40(4):396-9.
Miller, B. R., Monath, T. P., Tabachnick, W. J., & Ezike, V. I. (1989). Epidemic yellow fever caused by an incompetent mosquito vector. Tropical Medicine and Parasitology : Official Organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft Fur Technische Zusammenarbeit (GTZ), 40(4), 396-9.
Miller BR, et al. Epidemic Yellow Fever Caused By an Incompetent Mosquito Vector. Trop Med Parasitol. 1989;40(4):396-9. PubMed PMID: 2623418.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemic yellow fever caused by an incompetent mosquito vector. AU - Miller,B R, AU - Monath,T P, AU - Tabachnick,W J, AU - Ezike,V I, PY - 1989/12/1/pubmed PY - 1989/12/1/medline PY - 1989/12/1/entrez SP - 396 EP - 9 JF - Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ) JO - Trop Med Parasitol VL - 40 IS - 4 N2 - Arbovirus epidemics in a geographic region are believed to depend on the presence of susceptible or "competent" arthropod vectors. We demonstrate that an urban, Aedes aegypti-borne, epidemic of yellow fever occurred in 1987 although the mosquito vector was relatively resistant to infection and transmitted the virus inefficiently. Twenty-six percent of the experimental mosquitoes from the epidemic area that ingested yellow fever virus became infected and only 7% of these transmitted the virus. In contrast, 80% of an exotic susceptible strain of Ae. aegypti became infected and 43% were able to transmit. We also show that no other potential vectors were active during the epidemic and that the local Ae. aegypti were present in extremely large numbers. These results document, for the first time, that, in the presence of high population density an incompetent mosquito vector can initiate and maintain virus transmission resulting in an epidemic. SN - 0177-2392 UR - https://www.unboundmedicine.com/medline/citation/2623418/Epidemic_yellow_fever_caused_by_an_incompetent_mosquito_vector_ L2 - https://www.diseaseinfosearch.org/result/7583 DB - PRIME DP - Unbound Medicine ER -