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[Dose-effect relationships between blood lead and free erythrocyte protoporphyrin or zinc protoporphyrin].
Zhonghua Yu Fang Yi Xue Za Zhi. 1989 Sep; 23(5):279-82.ZY

Abstract

Studies on dose-effect relationships between blood lead (PbB) and free erythrocyte protoporphyrin (FEP) or zinc protoporphyrin (ZPP) in 583 workers (male 326, female 257) was conducted. Good dose-effect relationships and S-shaped curves between PbB and logFEP, logZPP or log (ZPP/Hb) were established. Sectioned linear regression showed that linear correlation was obtained while PbB between 0.48 (10 micrograms/dl) and 3.36 mumol/L (70 micrograms/dl) (male) or 0.48 (10 micrograms/dl) and 2.88 mumol/L (60 micrograms/dl) (female). However, while PbB below 0.48 mumol/L (10 micrograms/dl), there was no linear correlation. The increasing of FEP, ZPP slowed down remarkably as PbB were beyond 3.36 mumol/L (70 micrograms/dl) (male) or 2.88 mumol/L (60 micrograms/dl) (female). Therefore, the degree of lead poisoning can't be classified by the values of FEP, ZPP among plumbism.

Authors

Sun GL
No affiliation info available

MeSH

Dose-Response Relationship, DrugErythrocytesFemaleHumansLeadLead PoisoningMaleOccupational DiseasesPorphyrinsProtoporphyrinsSeverity of Illness Index

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

2625062

Citation

Sun, G L.. "[Dose-effect Relationships Between Blood Lead and Free Erythrocyte Protoporphyrin or Zinc Protoporphyrin]." Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine], vol. 23, no. 5, 1989, pp. 279-82.
Sun GL. [Dose-effect relationships between blood lead and free erythrocyte protoporphyrin or zinc protoporphyrin]. Zhonghua Yu Fang Yi Xue Za Zhi. 1989;23(5):279-82.
Sun, G. L. (1989). [Dose-effect relationships between blood lead and free erythrocyte protoporphyrin or zinc protoporphyrin]. Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine], 23(5), 279-82.
Sun GL. [Dose-effect Relationships Between Blood Lead and Free Erythrocyte Protoporphyrin or Zinc Protoporphyrin]. Zhonghua Yu Fang Yi Xue Za Zhi. 1989;23(5):279-82. PubMed PMID: 2625062.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Dose-effect relationships between blood lead and free erythrocyte protoporphyrin or zinc protoporphyrin]. A1 - Sun,G L, PY - 1989/9/1/pubmed PY - 1989/9/1/medline PY - 1989/9/1/entrez SP - 279 EP - 82 JF - Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] JO - Zhonghua Yu Fang Yi Xue Za Zhi VL - 23 IS - 5 N2 - Studies on dose-effect relationships between blood lead (PbB) and free erythrocyte protoporphyrin (FEP) or zinc protoporphyrin (ZPP) in 583 workers (male 326, female 257) was conducted. Good dose-effect relationships and S-shaped curves between PbB and logFEP, logZPP or log (ZPP/Hb) were established. Sectioned linear regression showed that linear correlation was obtained while PbB between 0.48 (10 micrograms/dl) and 3.36 mumol/L (70 micrograms/dl) (male) or 0.48 (10 micrograms/dl) and 2.88 mumol/L (60 micrograms/dl) (female). However, while PbB below 0.48 mumol/L (10 micrograms/dl), there was no linear correlation. The increasing of FEP, ZPP slowed down remarkably as PbB were beyond 3.36 mumol/L (70 micrograms/dl) (male) or 2.88 mumol/L (60 micrograms/dl) (female). Therefore, the degree of lead poisoning can't be classified by the values of FEP, ZPP among plumbism. SN - 0253-9624 UR - https://www.unboundmedicine.com/medline/citation/2625062/[Dose_effect_relationships_between_blood_lead_and_free_erythrocyte_protoporphyrin_or_zinc_protoporphyrin]_ DB - PRIME DP - Unbound Medicine ER -