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Subcutaneous mycoses in coastal Karnataka in south India.
Int J Dermatol. 2016 Jan; 55(1):70-8.IJ

Abstract

BACKGROUND

Subcutaneous mycoses are chronic, localized infections of the skin and subcutaneous tissue which occur following traumatic implantation of the etiological agent. The causative organisms are soil saprophytes of regional epidemiology with varying ability to adapt to the tissue environment and elicit disease.

OBJECTIVES

This study was conducted to evaluate the various types of subcutaneous mycoses, including actinomycotic mycetomas, in south coastal Karnataka, India.

METHODS

Between January 2005 and January 2013, a total of 25 patients were diagnosed with subcutaneous mycoses based on a detailed clinical history and presentation, histopathology, and culture of organisms.

RESULTS

Chromoblastomycosis was the infection most commonly seen (n = 16 patients, 64%), followed by mycetoma (n = 4, 16%), sporotrichosis (n = 4, 16%), and rhinoentomophthoromycosis (n = 1, 4%). The extremities were the most common site of involvement, with the lower limb being most affected (64%). Males were more commonly afflicted (64%) than females (36%). Most patients were agricultural workers, although preceding trauma was noted in only three patients. The majority of patients responded well to therapy and were disease-free on follow-up.

CONCLUSIONS

Subcutaneous mycoses are a rare group of disorders. Chromoblastomycosis is the most frequent subcutaneous fungal infection in south India. Morphologically, chromomoblastomycoses present as verrucous, ulcerative, nodular, or eczematous lesions. Clinical diagnosis is important as culture is often negative. The incidence of infection is higher among rubber tappers. It is important to clinically differentiate chromoblastomycosis from tuberculosis verrucosa cutis. Most of the subcutaneous mycoses respond well to treatment, with the exception of rhinoentomophthoromycosis, which is a rare form of deep mycosis with associated mutilation. Eumycetomas are not observed in this part of India.

Authors+Show Affiliations

Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India.Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India.Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India.Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India.Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India.Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India.Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India.Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26267755

Citation

Bhat, Ramesh M., et al. "Subcutaneous Mycoses in Coastal Karnataka in South India." International Journal of Dermatology, vol. 55, no. 1, 2016, pp. 70-8.
Bhat RM, Monteiro RC, Bala N, et al. Subcutaneous mycoses in coastal Karnataka in south India. Int J Dermatol. 2016;55(1):70-8.
Bhat, R. M., Monteiro, R. C., Bala, N., Dandakeri, S., Martis, J., Kamath, G. H., Kambil, S. M., & Asha Vadakayil, R. (2016). Subcutaneous mycoses in coastal Karnataka in south India. International Journal of Dermatology, 55(1), 70-8. https://doi.org/10.1111/ijd.12943
Bhat RM, et al. Subcutaneous Mycoses in Coastal Karnataka in South India. Int J Dermatol. 2016;55(1):70-8. PubMed PMID: 26267755.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Subcutaneous mycoses in coastal Karnataka in south India. AU - Bhat,Ramesh M, AU - Monteiro,Rochelle C, AU - Bala,Nandakishore, AU - Dandakeri,Sukumar, AU - Martis,Jacintha, AU - Kamath,Ganesh H, AU - Kambil,Srinath M, AU - Asha Vadakayil,Ramay, Y1 - 2015/08/12/ PY - 2014/03/06/received PY - 2014/10/27/revised PY - 2014/12/03/accepted PY - 2015/8/13/entrez PY - 2015/8/13/pubmed PY - 2016/11/10/medline SP - 70 EP - 8 JF - International journal of dermatology JO - Int J Dermatol VL - 55 IS - 1 N2 - BACKGROUND: Subcutaneous mycoses are chronic, localized infections of the skin and subcutaneous tissue which occur following traumatic implantation of the etiological agent. The causative organisms are soil saprophytes of regional epidemiology with varying ability to adapt to the tissue environment and elicit disease. OBJECTIVES: This study was conducted to evaluate the various types of subcutaneous mycoses, including actinomycotic mycetomas, in south coastal Karnataka, India. METHODS: Between January 2005 and January 2013, a total of 25 patients were diagnosed with subcutaneous mycoses based on a detailed clinical history and presentation, histopathology, and culture of organisms. RESULTS: Chromoblastomycosis was the infection most commonly seen (n = 16 patients, 64%), followed by mycetoma (n = 4, 16%), sporotrichosis (n = 4, 16%), and rhinoentomophthoromycosis (n = 1, 4%). The extremities were the most common site of involvement, with the lower limb being most affected (64%). Males were more commonly afflicted (64%) than females (36%). Most patients were agricultural workers, although preceding trauma was noted in only three patients. The majority of patients responded well to therapy and were disease-free on follow-up. CONCLUSIONS: Subcutaneous mycoses are a rare group of disorders. Chromoblastomycosis is the most frequent subcutaneous fungal infection in south India. Morphologically, chromomoblastomycoses present as verrucous, ulcerative, nodular, or eczematous lesions. Clinical diagnosis is important as culture is often negative. The incidence of infection is higher among rubber tappers. It is important to clinically differentiate chromoblastomycosis from tuberculosis verrucosa cutis. Most of the subcutaneous mycoses respond well to treatment, with the exception of rhinoentomophthoromycosis, which is a rare form of deep mycosis with associated mutilation. Eumycetomas are not observed in this part of India. SN - 1365-4632 UR - https://www.unboundmedicine.com/medline/citation/26267755/Subcutaneous_mycoses_in_coastal_Karnataka_in_south_India_ L2 - https://doi.org/10.1111/ijd.12943 DB - PRIME DP - Unbound Medicine ER -