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Functional status and mortality at month and year in nonagenarians hospitalized due to acute medical illness.
Eur J Intern Med. 2015 Nov; 26(9):705-8.EJ

Abstract

OBJECTIVES

To analyze risk factors associated with short and long-term mortality in nonagenarians hospitalized due to acute medical conditions.

DESIGN, SETTING, AND PARTICIPANTS

Prospective study of all patients aged 90 years or older admitted in a geriatric unit during 2009 due to medical acute illness. Baseline variables were collected at admission (sex, cause of admission, Charlson index, serum albumin, functional, and mental status), functional loss at admission (as the difference between Barthel index(BI) 2 weeks before admission and BI at admission), and functional loss at discharge(as the difference between BI 2 weeks before admission and BI at discharge). The association of these variables with mortality at 1 month and 1 year after admission was analyzed by multivariate Cox regression analysis.

RESULTS

Out of all patients admitted, 434 (33%) were 90 years old or older and 76.3% were female. Mortality at 1 month and 1 year after admission was 19% and 57%, respectively. In the month mortality multivariate analysis, being older (HR, 1.11; 95% CI=1.02 to 1.20), a previous Barthel index less than 40 points (HR, 5.87; 95% CI=1.16 to 29.67), and functional loss at admission (HR; 1.13; 95% CI=1.03 to 1.25) were independent risk factors. When patients that died 1 month after admission were excluded, the presence of hypoalbuminemia <3g/dl (HR, 2.70; 95% CI=1.69 to 4.32) and functional loss at discharge (HR-1.08, 95% CI=1.03 to 1.14) were the factors associated with 1 year mortality.

CONCLUSIONS

In nonagenarians, functional impairment is the most important risk factor associated with short and long-term mortality after hospitalization due to acute medical illness.

Authors+Show Affiliations

Department of Geriatrics, Hospital Central de la Cruz Roja, San José y Santa Adela, Madrid, Spain. Electronic address: asocorrog@yahoo.es.Department of Geriatrics, Hospital Central de la Cruz Roja, San José y Santa Adela, Madrid, Spain.Department of Geriatrics, Hospital Central de la Cruz Roja, San José y Santa Adela, Madrid, Spain.Department of Geriatrics, Hospital Central de la Cruz Roja, San José y Santa Adela, Madrid, Spain.Department of Geriatrics, Hospital Central de la Cruz Roja, San José y Santa Adela, Madrid, Spain.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26320014

Citation

Socorro García, Alberto, et al. "Functional Status and Mortality at Month and Year in Nonagenarians Hospitalized Due to Acute Medical Illness." European Journal of Internal Medicine, vol. 26, no. 9, 2015, pp. 705-8.
Socorro García A, de la Puente M, Perdomo B, et al. Functional status and mortality at month and year in nonagenarians hospitalized due to acute medical illness. Eur J Intern Med. 2015;26(9):705-8.
Socorro García, A., de la Puente, M., Perdomo, B., López Pardo, P., & Baztán, J. J. (2015). Functional status and mortality at month and year in nonagenarians hospitalized due to acute medical illness. European Journal of Internal Medicine, 26(9), 705-8. https://doi.org/10.1016/j.ejim.2015.08.007
Socorro García A, et al. Functional Status and Mortality at Month and Year in Nonagenarians Hospitalized Due to Acute Medical Illness. Eur J Intern Med. 2015;26(9):705-8. PubMed PMID: 26320014.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Functional status and mortality at month and year in nonagenarians hospitalized due to acute medical illness. AU - Socorro García,Alberto, AU - de la Puente,María, AU - Perdomo,Beatriz, AU - López Pardo,Patricia, AU - Baztán,Juan J, Y1 - 2015/08/28/ PY - 2015/04/24/received PY - 2015/08/05/revised PY - 2015/08/10/accepted PY - 2015/8/31/entrez PY - 2015/9/1/pubmed PY - 2016/9/13/medline KW - Hospitalization KW - Mortality KW - Nonagenarians SP - 705 EP - 8 JF - European journal of internal medicine JO - Eur. J. Intern. Med. VL - 26 IS - 9 N2 - OBJECTIVES: To analyze risk factors associated with short and long-term mortality in nonagenarians hospitalized due to acute medical conditions. DESIGN, SETTING, AND PARTICIPANTS: Prospective study of all patients aged 90 years or older admitted in a geriatric unit during 2009 due to medical acute illness. Baseline variables were collected at admission (sex, cause of admission, Charlson index, serum albumin, functional, and mental status), functional loss at admission (as the difference between Barthel index(BI) 2 weeks before admission and BI at admission), and functional loss at discharge(as the difference between BI 2 weeks before admission and BI at discharge). The association of these variables with mortality at 1 month and 1 year after admission was analyzed by multivariate Cox regression analysis. RESULTS: Out of all patients admitted, 434 (33%) were 90 years old or older and 76.3% were female. Mortality at 1 month and 1 year after admission was 19% and 57%, respectively. In the month mortality multivariate analysis, being older (HR, 1.11; 95% CI=1.02 to 1.20), a previous Barthel index less than 40 points (HR, 5.87; 95% CI=1.16 to 29.67), and functional loss at admission (HR; 1.13; 95% CI=1.03 to 1.25) were independent risk factors. When patients that died 1 month after admission were excluded, the presence of hypoalbuminemia <3g/dl (HR, 2.70; 95% CI=1.69 to 4.32) and functional loss at discharge (HR-1.08, 95% CI=1.03 to 1.14) were the factors associated with 1 year mortality. CONCLUSIONS: In nonagenarians, functional impairment is the most important risk factor associated with short and long-term mortality after hospitalization due to acute medical illness. SN - 1879-0828 UR - https://www.unboundmedicine.com/medline/citation/26320014/Functional_status_and_mortality_at_month_and_year_in_nonagenarians_hospitalized_due_to_acute_medical_illness_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0953-6205(15)00254-X DB - PRIME DP - Unbound Medicine ER -