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Sporadic intramedullary hemangioblastoma of the spine: a single institutional review of 21 cases.
Neurol Res. 2016 Mar; 38(3):205-9.NR

Abstract

INTRODUCTION

Sporadic intramedullary spinal cord hemangioblastomas are rare, vascular tumours that can present with significant neurological dysfunction. Surgical resection is the standard treatment for these lesions, and we report our institution's experience with patients who underwent surgery for sporadic intramedullary spinal cord hemangioblastomas.

METHODS

We retrospectively reviewed 21 patients (14 male, 7 female) who underwent a total of 23 surgeries for sporadic intramedullary spinal cord hemangioblastoma between 1996 and 2014.We recorded demographic, operative and postoperative factors.

RESULTS

The median age was 45 years (IQR: 28). All tumours were present in the cervical (13 of 21, 62%) or thoracic (nine of 21, 43%) spine (one patient had tumours in both locations). Thirteen patients (62%) also had concurrent syringomyelia spanning a median of 11 vertebral levels (IQR: 5). Total resection was achieved in all but one surgery, and no cases involved intraoperative complications. However, postoperative complications occurred after five cases. Median follow-up was 12 months (IQR: 38). Twelve patients (57%) experienced long-term dysfunction after surgery, and two patients experienced recurrence requiring a second surgery.

CONCLUSIONS

Maximal safe surgical resection should be considered as a primary treatment modality for individuals with intramedullary spinal cord hemangioblastomas.

Authors+Show Affiliations

a Department of Neurosurgery , Johns Hopkins Hospital , Baltimore , MD , USA.b Department of Orthopedic Surgery , Johns Hopkins Hospital , Baltimore , MD , USA.a Department of Neurosurgery , Johns Hopkins Hospital , Baltimore , MD , USA.a Department of Neurosurgery , Johns Hopkins Hospital , Baltimore , MD , USA.a Department of Neurosurgery , Johns Hopkins Hospital , Baltimore , MD , USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

26355433

Citation

Liu, Ann, et al. "Sporadic Intramedullary Hemangioblastoma of the Spine: a Single Institutional Review of 21 Cases." Neurological Research, vol. 38, no. 3, 2016, pp. 205-9.
Liu A, Jain A, Sankey EW, et al. Sporadic intramedullary hemangioblastoma of the spine: a single institutional review of 21 cases. Neurol Res. 2016;38(3):205-9.
Liu, A., Jain, A., Sankey, E. W., Jallo, G. I., & Bettegowda, C. (2016). Sporadic intramedullary hemangioblastoma of the spine: a single institutional review of 21 cases. Neurological Research, 38(3), 205-9. https://doi.org/10.1179/1743132815Y.0000000097
Liu A, et al. Sporadic Intramedullary Hemangioblastoma of the Spine: a Single Institutional Review of 21 Cases. Neurol Res. 2016;38(3):205-9. PubMed PMID: 26355433.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sporadic intramedullary hemangioblastoma of the spine: a single institutional review of 21 cases. AU - Liu,Ann, AU - Jain,Amit, AU - Sankey,Eric W, AU - Jallo,George I, AU - Bettegowda,Chetan, Y1 - 2016/04/19/ PY - 2015/9/11/entrez PY - 2015/9/12/pubmed PY - 2017/1/14/medline KW - Hemangioblastoma KW - Oncology KW - Spine SP - 205 EP - 9 JF - Neurological research JO - Neurol. Res. VL - 38 IS - 3 N2 - INTRODUCTION: Sporadic intramedullary spinal cord hemangioblastomas are rare, vascular tumours that can present with significant neurological dysfunction. Surgical resection is the standard treatment for these lesions, and we report our institution's experience with patients who underwent surgery for sporadic intramedullary spinal cord hemangioblastomas. METHODS: We retrospectively reviewed 21 patients (14 male, 7 female) who underwent a total of 23 surgeries for sporadic intramedullary spinal cord hemangioblastoma between 1996 and 2014.We recorded demographic, operative and postoperative factors. RESULTS: The median age was 45 years (IQR: 28). All tumours were present in the cervical (13 of 21, 62%) or thoracic (nine of 21, 43%) spine (one patient had tumours in both locations). Thirteen patients (62%) also had concurrent syringomyelia spanning a median of 11 vertebral levels (IQR: 5). Total resection was achieved in all but one surgery, and no cases involved intraoperative complications. However, postoperative complications occurred after five cases. Median follow-up was 12 months (IQR: 38). Twelve patients (57%) experienced long-term dysfunction after surgery, and two patients experienced recurrence requiring a second surgery. CONCLUSIONS: Maximal safe surgical resection should be considered as a primary treatment modality for individuals with intramedullary spinal cord hemangioblastomas. SN - 1743-1328 UR - https://www.unboundmedicine.com/medline/citation/26355433/Sporadic_intramedullary_hemangioblastoma_of_the_spine:_a_single_institutional_review_of_21_cases_ DB - PRIME DP - Unbound Medicine ER -