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FDG PET/CT in Early and Late Stages of SAPHO Syndrome: Two Case Reports With MRI and Bone Scintigraphy Correlation.
Clin Nucl Med 2016; 41(4):e211-5CN

Abstract

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare disease, which may be underdiagnosed or misdiagnosed because of nonspecific clinical and imaging findings. We present 2 cases of SAPHO syndrome with MRI, bone scintigraphy, and FDG PET/CT findings. In case 1 with early-stage disease, the active osteitis showed osteolytic bone destruction with increased FDG uptake. In case 2 with late-stage disease, the inactive bone lesions presented as osteosclerosis with normal FDG uptake. Familiarity with the FDG PET/CT findings of SAPHO syndrome in different stages may be helpful for correct diagnosis.

Authors+Show Affiliations

From the Departments of *Nuclear Medicine and †Orthopaedic Surgery, Changhai Hospital, Second Military Medical University, Shanghai; ‡Department of Cardiothoracic Surgery, Lvcheng Hospital, Hangzhou, Zhejiang Province, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

26359576

Citation

Dong, Aisheng, et al. "FDG PET/CT in Early and Late Stages of SAPHO Syndrome: Two Case Reports With MRI and Bone Scintigraphy Correlation." Clinical Nuclear Medicine, vol. 41, no. 4, 2016, pp. e211-5.
Dong A, Bai Y, Cui Y, et al. FDG PET/CT in Early and Late Stages of SAPHO Syndrome: Two Case Reports With MRI and Bone Scintigraphy Correlation. Clin Nucl Med. 2016;41(4):e211-5.
Dong, A., Bai, Y., Cui, Y., Zhang, J., & Zuo, C. (2016). FDG PET/CT in Early and Late Stages of SAPHO Syndrome: Two Case Reports With MRI and Bone Scintigraphy Correlation. Clinical Nuclear Medicine, 41(4), pp. e211-5. doi:10.1097/RLU.0000000000000983.
Dong A, et al. FDG PET/CT in Early and Late Stages of SAPHO Syndrome: Two Case Reports With MRI and Bone Scintigraphy Correlation. Clin Nucl Med. 2016;41(4):e211-5. PubMed PMID: 26359576.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - FDG PET/CT in Early and Late Stages of SAPHO Syndrome: Two Case Reports With MRI and Bone Scintigraphy Correlation. AU - Dong,Aisheng, AU - Bai,Yushu, AU - Cui,Yong, AU - Zhang,Jian, AU - Zuo,Changjing, PY - 2015/9/12/entrez PY - 2015/9/12/pubmed PY - 2016/11/5/medline SP - e211 EP - 5 JF - Clinical nuclear medicine JO - Clin Nucl Med VL - 41 IS - 4 N2 - Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare disease, which may be underdiagnosed or misdiagnosed because of nonspecific clinical and imaging findings. We present 2 cases of SAPHO syndrome with MRI, bone scintigraphy, and FDG PET/CT findings. In case 1 with early-stage disease, the active osteitis showed osteolytic bone destruction with increased FDG uptake. In case 2 with late-stage disease, the inactive bone lesions presented as osteosclerosis with normal FDG uptake. Familiarity with the FDG PET/CT findings of SAPHO syndrome in different stages may be helpful for correct diagnosis. SN - 1536-0229 UR - https://www.unboundmedicine.com/medline/citation/26359576/FDG_PET/CT_in_Early_and_Late_Stages_of_SAPHO_Syndrome:_Two_Case_Reports_With_MRI_and_Bone_Scintigraphy_Correlation_ L2 - https://dx.doi.org/10.1097/RLU.0000000000000983 DB - PRIME DP - Unbound Medicine ER -