Tags

Type your tag names separated by a space and hit enter

Impulse oscillometry in acute and stable asthmatic children: a comparison with spirometry.
J Asthma. 2016; 53(2):179-86.JA

Abstract

OBJECTIVE

Lung function tests have attracted interest for the diagnosis and follow-up of childhood asthma in recent years. For patients who cannot perform forced expiratory maneuvers, impulse oscillometry (IOS), performed during spontaneous breathing, may be an alternative tool.

METHODS

Thirty-five acute, 107 stable asthmatic and 103 healthy children who presented to our clinic performed IOS followed by spirometry before and after salbutamol inhalation. The mean baseline and reversibility of IOS and spirometry parameters were compared between the groups. Correlation analyses were undertaken within the asthmatics, and the healthy controls separately. To distinguish the three groups, the sensitivity and specificity of baseline and reversibility values of IOS and spirometry were computed. When spirometry was taken as the gold standard, the discriminating performance of IOS to detect the airway obstruction and reversibility was investigated.

RESULTS

The mean absolute values of Zrs, R5, R5-R20, X5, X10, X15, Fres, AX, and all spirometric parameters, and the mean reversibility values of R5, R10, Fres, AX and forced expiratory volume in one second were different between the groups and the highest area under curve values to discriminate the groups was obtained from area of reactance (AX) and ΔAX. Zrs, all resistance (including R5-R20) and reactance parameters, Fres and AX were correlated with at least one spirometric parameter. Spirometric reversibility was detected by ≤-22.34 and ≤-39.05 cut-off values of ΔR5 and ΔAX, respectively.

CONCLUSIONS

IOS has shown a highly significant association with spirometric indices and reversibility testing. It may be a substitute for spirometry in children who fail to perform forced expiratory maneuvers.

Authors+Show Affiliations

a Division of Allergy and Immunology, Department of Pediatrics , Medical School, Mersin University , Mersin , Turkey and.a Division of Allergy and Immunology, Department of Pediatrics , Medical School, Mersin University , Mersin , Turkey and.a Division of Allergy and Immunology, Department of Pediatrics , Medical School, Mersin University , Mersin , Turkey and.b Pediatrics Clinic, Kars State Hospital , Kars , Turkey.a Division of Allergy and Immunology, Department of Pediatrics , Medical School, Mersin University , Mersin , Turkey and.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

26367097

Citation

Batmaz, Sehra Birgul, et al. "Impulse Oscillometry in Acute and Stable Asthmatic Children: a Comparison With Spirometry." The Journal of Asthma : Official Journal of the Association for the Care of Asthma, vol. 53, no. 2, 2016, pp. 179-86.
Batmaz SB, Kuyucu S, Arıkoglu T, et al. Impulse oscillometry in acute and stable asthmatic children: a comparison with spirometry. J Asthma. 2016;53(2):179-86.
Batmaz, S. B., Kuyucu, S., Arıkoglu, T., Tezol, O., & Aydogdu, A. (2016). Impulse oscillometry in acute and stable asthmatic children: a comparison with spirometry. The Journal of Asthma : Official Journal of the Association for the Care of Asthma, 53(2), 179-86. https://doi.org/10.3109/02770903.2015.1081699
Batmaz SB, et al. Impulse Oscillometry in Acute and Stable Asthmatic Children: a Comparison With Spirometry. J Asthma. 2016;53(2):179-86. PubMed PMID: 26367097.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impulse oscillometry in acute and stable asthmatic children: a comparison with spirometry. AU - Batmaz,Sehra Birgul, AU - Kuyucu,Semanur, AU - Arıkoglu,Tugba, AU - Tezol,Ozlem, AU - Aydogdu,Ayse, Y1 - 2015/09/14/ PY - 2015/9/15/entrez PY - 2015/9/15/pubmed PY - 2016/7/29/medline KW - Childhood KW - impulse oscillometry KW - reversibility KW - spirometry SP - 179 EP - 86 JF - The Journal of asthma : official journal of the Association for the Care of Asthma JO - J Asthma VL - 53 IS - 2 N2 - OBJECTIVE: Lung function tests have attracted interest for the diagnosis and follow-up of childhood asthma in recent years. For patients who cannot perform forced expiratory maneuvers, impulse oscillometry (IOS), performed during spontaneous breathing, may be an alternative tool. METHODS: Thirty-five acute, 107 stable asthmatic and 103 healthy children who presented to our clinic performed IOS followed by spirometry before and after salbutamol inhalation. The mean baseline and reversibility of IOS and spirometry parameters were compared between the groups. Correlation analyses were undertaken within the asthmatics, and the healthy controls separately. To distinguish the three groups, the sensitivity and specificity of baseline and reversibility values of IOS and spirometry were computed. When spirometry was taken as the gold standard, the discriminating performance of IOS to detect the airway obstruction and reversibility was investigated. RESULTS: The mean absolute values of Zrs, R5, R5-R20, X5, X10, X15, Fres, AX, and all spirometric parameters, and the mean reversibility values of R5, R10, Fres, AX and forced expiratory volume in one second were different between the groups and the highest area under curve values to discriminate the groups was obtained from area of reactance (AX) and ΔAX. Zrs, all resistance (including R5-R20) and reactance parameters, Fres and AX were correlated with at least one spirometric parameter. Spirometric reversibility was detected by ≤-22.34 and ≤-39.05 cut-off values of ΔR5 and ΔAX, respectively. CONCLUSIONS: IOS has shown a highly significant association with spirometric indices and reversibility testing. It may be a substitute for spirometry in children who fail to perform forced expiratory maneuvers. SN - 1532-4303 UR - https://www.unboundmedicine.com/medline/citation/26367097/Impulse_oscillometry_in_acute_and_stable_asthmatic_children:_a_comparison_with_spirometry_ L2 - http://www.tandfonline.com/doi/full/10.3109/02770903.2015.1081699 DB - PRIME DP - Unbound Medicine ER -