Tags

Type your tag names separated by a space and hit enter

The needle glucose electrode: in vitro performance and optimisation for implantation.
Biomed Biochim Acta. 1989; 48(11-12):935-42.BB

Abstract

The classical glucose needle electrode based on detection of H2O2 from glucose oxidase has been studied. Dip-coating of a series of outer polyurethane layers of increasing concentration (10-50% W/V) achieved devices with extended linearity (greater than or equal to 30 mM glucose) with greater reliability than a single dip-coat. In vitro performance in unstirred whole blood was acceptable, and all devices were stir-independent. Nevertheless, signal size was affected by a high solution viscosity, and this may have implications for the use of enzyme electrodes in subcutaneous tissue.

Authors+Show Affiliations

Department of Clinical Biochemistry, Medical School, Newcastle upon Tyne, U.K.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2636838

Citation

Vadgama, P, et al. "The Needle Glucose Electrode: in Vitro Performance and Optimisation for Implantation." Biomedica Biochimica Acta, vol. 48, no. 11-12, 1989, pp. 935-42.
Vadgama P, Spoors J, Tang LX, et al. The needle glucose electrode: in vitro performance and optimisation for implantation. Biomed Biochim Acta. 1989;48(11-12):935-42.
Vadgama, P., Spoors, J., Tang, L. X., & Battersby, C. (1989). The needle glucose electrode: in vitro performance and optimisation for implantation. Biomedica Biochimica Acta, 48(11-12), 935-42.
Vadgama P, et al. The Needle Glucose Electrode: in Vitro Performance and Optimisation for Implantation. Biomed Biochim Acta. 1989;48(11-12):935-42. PubMed PMID: 2636838.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The needle glucose electrode: in vitro performance and optimisation for implantation. AU - Vadgama,P, AU - Spoors,J, AU - Tang,L X, AU - Battersby,C, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 935 EP - 42 JF - Biomedica biochimica acta JO - Biomed Biochim Acta VL - 48 IS - 11-12 N2 - The classical glucose needle electrode based on detection of H2O2 from glucose oxidase has been studied. Dip-coating of a series of outer polyurethane layers of increasing concentration (10-50% W/V) achieved devices with extended linearity (greater than or equal to 30 mM glucose) with greater reliability than a single dip-coat. In vitro performance in unstirred whole blood was acceptable, and all devices were stir-independent. Nevertheless, signal size was affected by a high solution viscosity, and this may have implications for the use of enzyme electrodes in subcutaneous tissue. SN - 0232-766X UR - https://www.unboundmedicine.com/medline/citation/2636838/The_needle_glucose_electrode:_in_vitro_performance_and_optimisation_for_implantation_ L2 - https://medlineplus.gov/bloodsugar.html DB - PRIME DP - Unbound Medicine ER -