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Prospective association between cancer risk and an individual dietary index based on the British Food Standards Agency Nutrient Profiling System.
Br J Nutr. 2015 Nov 28; 114(10):1702-10.BJ

Abstract

The Food Standards Agency Nutrient Profiling System (FSA-NPS) constitutes the basis for the Five-Colour Nutrition Label suggested in France to be put on the front-of-pack of food products. At the individual level, a dietary index (FSA-NPS DI) has been derived and validated and corresponds to a weighted mean of all FSA-NPS scores of foods usually consumed by the individual, reflecting the nutritional quality of his/her diet. Our aim was to investigate the association between the FSA-NPS DI and cancer risk in a large cohort. This prospective study included 6435 participants to the SUpplémentation en VItamines et Minéraux AntioXydants cohort (1994-2007) who completed at least six 24 h dietary records during the first 2 years of follow-up. FSA-NPS DI was computed for each subject (higher values representing lower nutritional quality of the diet). After a median follow-up of 12·6 years, 453 incident cancers were diagnosed. Associations were characterised by multivariate Cox proportional hazards models. The FSA-NPS DI was directly associated with overall cancer risk (hazard ratio (HR)for a 1-point increment=1·08 (95 % CI 1·01, 1·15), P trend=0·02; HRQ5 v. Q1=1·34 (95 % CI 1·00, 1·81), P trend=0·03). This association tended to be more specifically observed in subjects with moderate energy intake (≤median, HRfor a 1-point increment=1·10 (95 % CI 1·01-1·20), P trend=0·03). No association was observed in subjects with higher energy intake (P trend=0·3). Results were not statistically significant for breast and prostate cancer risks. For the first time, this study investigated the prospective association between the FSA-NPS individual score and cancer risk. The results suggest that unhealthy food choices may be associated with a 34 % increase in overall cancer risk, supporting the public health relevance of developing front-of-pack nutrition labels based on this score.

Authors+Show Affiliations

1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.1Centre de Recherche en Epidémiologie et Statistiques,Equipe de Recherche en Epidémiologie Nutritionnelle (EREN),Université Paris 13,Inserm (U1153),Inra (U1125),Cnam,COMUE Sorbonne Paris Cité,F-93017 Bobigny,France.

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26393396

Citation

Donnenfeld, Mathilde, et al. "Prospective Association Between Cancer Risk and an Individual Dietary Index Based On the British Food Standards Agency Nutrient Profiling System." The British Journal of Nutrition, vol. 114, no. 10, 2015, pp. 1702-10.
Donnenfeld M, Julia C, Kesse-Guyot E, et al. Prospective association between cancer risk and an individual dietary index based on the British Food Standards Agency Nutrient Profiling System. Br J Nutr. 2015;114(10):1702-10.
Donnenfeld, M., Julia, C., Kesse-Guyot, E., Méjean, C., Ducrot, P., Péneau, S., Deschasaux, M., Latino-Martel, P., Fezeu, L., Hercberg, S., & Touvier, M. (2015). Prospective association between cancer risk and an individual dietary index based on the British Food Standards Agency Nutrient Profiling System. The British Journal of Nutrition, 114(10), 1702-10. https://doi.org/10.1017/S0007114515003384
Donnenfeld M, et al. Prospective Association Between Cancer Risk and an Individual Dietary Index Based On the British Food Standards Agency Nutrient Profiling System. Br J Nutr. 2015 Nov 28;114(10):1702-10. PubMed PMID: 26393396.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prospective association between cancer risk and an individual dietary index based on the British Food Standards Agency Nutrient Profiling System. AU - Donnenfeld,Mathilde, AU - Julia,Chantal, AU - Kesse-Guyot,Emmanuelle, AU - Méjean,Caroline, AU - Ducrot,Pauline, AU - Péneau,Sandrine, AU - Deschasaux,Mélanie, AU - Latino-Martel,Paule, AU - Fezeu,Léopold, AU - Hercberg,Serge, AU - Touvier,Mathilde, Y1 - 2015/09/23/ PY - 2015/9/23/entrez PY - 2015/9/24/pubmed PY - 2016/2/2/medline KW - Cancer risk KW - FSA-NPS DI Food Standards Agency Nutrient Profiling System Dietary Index KW - Food Standards Agency Nutrient Profiling System KW - HR hazard ratio KW - Nutrient profiling systems KW - Nutrition policy KW - Prospective studies KW - SU.VI.MAX SUpplémentation en VItamines et Minéraux AntioXydants SP - 1702 EP - 10 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 114 IS - 10 N2 - The Food Standards Agency Nutrient Profiling System (FSA-NPS) constitutes the basis for the Five-Colour Nutrition Label suggested in France to be put on the front-of-pack of food products. At the individual level, a dietary index (FSA-NPS DI) has been derived and validated and corresponds to a weighted mean of all FSA-NPS scores of foods usually consumed by the individual, reflecting the nutritional quality of his/her diet. Our aim was to investigate the association between the FSA-NPS DI and cancer risk in a large cohort. This prospective study included 6435 participants to the SUpplémentation en VItamines et Minéraux AntioXydants cohort (1994-2007) who completed at least six 24 h dietary records during the first 2 years of follow-up. FSA-NPS DI was computed for each subject (higher values representing lower nutritional quality of the diet). After a median follow-up of 12·6 years, 453 incident cancers were diagnosed. Associations were characterised by multivariate Cox proportional hazards models. The FSA-NPS DI was directly associated with overall cancer risk (hazard ratio (HR)for a 1-point increment=1·08 (95 % CI 1·01, 1·15), P trend=0·02; HRQ5 v. Q1=1·34 (95 % CI 1·00, 1·81), P trend=0·03). This association tended to be more specifically observed in subjects with moderate energy intake (≤median, HRfor a 1-point increment=1·10 (95 % CI 1·01-1·20), P trend=0·03). No association was observed in subjects with higher energy intake (P trend=0·3). Results were not statistically significant for breast and prostate cancer risks. For the first time, this study investigated the prospective association between the FSA-NPS individual score and cancer risk. The results suggest that unhealthy food choices may be associated with a 34 % increase in overall cancer risk, supporting the public health relevance of developing front-of-pack nutrition labels based on this score. SN - 1475-2662 UR - https://www.unboundmedicine.com/medline/citation/26393396/Prospective_association_between_cancer_risk_and_an_individual_dietary_index_based_on_the_British_Food_Standards_Agency_Nutrient_Profiling_System_ L2 - https://www.cambridge.org/core/product/identifier/S0007114515003384/type/journal_article DB - PRIME DP - Unbound Medicine ER -