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Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients.
Anesth Prog 2015; 62(3):91-9AP

Abstract

The study investigated patient discharge parameters and postdischarge adverse events after discharge among children who received oral conscious sedation for dental treatment. This prospective study involved 51 patients needing dental treatment under oral conscious sedation. Each patient received one of various regimens involving combinations of a narcotic (ie, morphine or meperidine), a sedative-hypnotic (ie, chloral hydrate), a benzodiazepine (ie, midazolam or diazepam), and/or an antihistamine (ie, hydroxyzine HCl). Nitrous oxide and local anesthesia were used in conjunction with all regimens. After written informed consent was obtained, each guardian was contacted by phone with specific questions in regard to adverse events following the dental appointment. Out of 51 sedation visits, 46 were utilized for analysis including 23 boys and 23 girls ranging from 2 years 2 months to 10 years old (mean 5.8 years). 60.1% of patients slept in the car on the way home, while 21.4% of that group was difficult to awaken upon reaching home. At home, 76.1% of patients slept; furthermore, 85.7% of patients who napped following the dental visit slept longer than usual. After the appointment, 19.6% exhibited nausea, 10.1% vomited, and 7.0% experienced a fever. A return to normal behavior was reported as follows: 17.4% in <2 hours, 39.1% in 2-6 hours, 28.3% in 6-10 hours, and 15.2% in >10 hours. Postdischarge excessive somnolence, nausea, and emesis were frequent complications. The time to normality ranged until the following morning demonstrating the importance of careful postdischarge adult supervision.

Authors+Show Affiliations

Assistant Professor of Clinical Dentistry in Pediatric Dentistry, Herman Ostrow School of Dentistry of University of Southern California, Los Angeles, California.Graduate Clinic Director of Pediatric Dentistry, Herman Ostrow School of Dentistry of University of Southern California, Los Angeles, California.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

26398124

Citation

Huang, Annie, and Thomas Tanbonliong. "Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients." Anesthesia Progress, vol. 62, no. 3, 2015, pp. 91-9.
Huang A, Tanbonliong T. Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients. Anesth Prog. 2015;62(3):91-9.
Huang, A., & Tanbonliong, T. (2015). Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients. Anesthesia Progress, 62(3), pp. 91-9. doi:10.2344/0003-3006-62.3.91.
Huang A, Tanbonliong T. Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients. Anesth Prog. 2015;62(3):91-9. PubMed PMID: 26398124.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients. AU - Huang,Annie, AU - Tanbonliong,Thomas, PY - 2015/9/24/entrez PY - 2015/9/24/pubmed PY - 2016/1/8/medline KW - Chloral hydrate KW - Conscious sedation KW - Dental treatment KW - Diazepam KW - Hydroxyzine KW - Meperidine KW - Midazolam KW - Morphine KW - Postdischarge adverse event SP - 91 EP - 9 JF - Anesthesia progress JO - Anesth Prog VL - 62 IS - 3 N2 - The study investigated patient discharge parameters and postdischarge adverse events after discharge among children who received oral conscious sedation for dental treatment. This prospective study involved 51 patients needing dental treatment under oral conscious sedation. Each patient received one of various regimens involving combinations of a narcotic (ie, morphine or meperidine), a sedative-hypnotic (ie, chloral hydrate), a benzodiazepine (ie, midazolam or diazepam), and/or an antihistamine (ie, hydroxyzine HCl). Nitrous oxide and local anesthesia were used in conjunction with all regimens. After written informed consent was obtained, each guardian was contacted by phone with specific questions in regard to adverse events following the dental appointment. Out of 51 sedation visits, 46 were utilized for analysis including 23 boys and 23 girls ranging from 2 years 2 months to 10 years old (mean 5.8 years). 60.1% of patients slept in the car on the way home, while 21.4% of that group was difficult to awaken upon reaching home. At home, 76.1% of patients slept; furthermore, 85.7% of patients who napped following the dental visit slept longer than usual. After the appointment, 19.6% exhibited nausea, 10.1% vomited, and 7.0% experienced a fever. A return to normal behavior was reported as follows: 17.4% in <2 hours, 39.1% in 2-6 hours, 28.3% in 6-10 hours, and 15.2% in >10 hours. Postdischarge excessive somnolence, nausea, and emesis were frequent complications. The time to normality ranged until the following morning demonstrating the importance of careful postdischarge adult supervision. SN - 0003-3006 UR - https://www.unboundmedicine.com/medline/citation/26398124/Oral_Sedation_Postdischarge_Adverse_Events_in_Pediatric_Dental_Patients_ L2 - http://www.anesthesiaprogress.org/doi/10.2344/0003-3006-62.3.91?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -