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Patients' satisfaction with therapy methods of advanced chronic venous disease.
Int Angiol. 2016 Feb; 35(1):98-107.IA

Abstract

BACKGROUND

To assess patients' satisfaction from the therapy of advanced chronic venous disorders (CVD) in everyday clinical practice in Poland, and to compare the efficacy of various venoactive drugs (VADs) in venous ulcers healing process.

METHODS

Seven hundred and eighty unselected adult patients with active (N.=441) or healed (N.=339) venous ulcers participated in the non-interventional observational 6-week study.

RESULTS

Compression therapy and VADs were utilized by 81.5% and 89.2% of patients respectively: 31.2% of all patients underwent surgical procedures for vein incompetence, 61.3% were satisfied with surgical methods, 43% with compression therapy, and 32.6% with VADs ‑ with highest rate of satisfied patients in the group taking Ruscus aculeatus and HMC and ascorbic acid (51.4%). Of 377 patients with active venous ulcers smaller than 200 cm2, adherent to VADs, 18.0% have been cured, and 66.6% have improved during 6-week period of observation. Multiple logistic regression analysis revealed that the compression therapy (OR=2.74), the size of ulcer ≤10 cm2 (OR=2.70) were increasing the change of ulcer healing. No VADs was better than another in the healing process.

CONCLUSION

1) Compression therapy and VADs are highly utilized by patients with advanced CVD. 2) Patients are more satisfied with surgical than conservative treatment of advanced CVD. 3) More than half of the patients with the advanced stage CVD taking Ruscus aculeatus and HMC and ascorbic acid is satisfied with the obtained improvement. 4) Ruscus aculeatus and HMC and ascorbic acid is similarly effective as other frequently used VADs in venous ulcer healing. 5) Ruscus aculeatus and HMC and ascorbic acid exerting effects on veins, capillaries and lymphatic vessels may explain the positive results observed in this study.

Authors+Show Affiliations

Department of Pathophysiology, Medical Faculty in Katowice, Medical University of Silesia, Katowice, Poland - chj@poczta.fm.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26406967

Citation

Chudek, Jerzy, et al. "Patients' Satisfaction With Therapy Methods of Advanced Chronic Venous Disease." International Angiology : a Journal of the International Union of Angiology, vol. 35, no. 1, 2016, pp. 98-107.
Chudek J, Mikosiński J, Kobielski A, et al. Patients' satisfaction with therapy methods of advanced chronic venous disease. Int Angiol. 2016;35(1):98-107.
Chudek, J., Mikosiński, J., Kobielski, A., Hering, A., Aleksiejew-Kleszczyński, T., Umiński, J., Zubilewicz, T., Kobusiewicz, W., Iłżecki, M., Wojtak, A., Stec, J., & Urbanek, T. (2016). Patients' satisfaction with therapy methods of advanced chronic venous disease. International Angiology : a Journal of the International Union of Angiology, 35(1), 98-107.
Chudek J, et al. Patients' Satisfaction With Therapy Methods of Advanced Chronic Venous Disease. Int Angiol. 2016;35(1):98-107. PubMed PMID: 26406967.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Patients' satisfaction with therapy methods of advanced chronic venous disease. AU - Chudek,Jerzy, AU - Mikosiński,Jacek, AU - Kobielski,Andrzej, AU - Hering,Artur, AU - Aleksiejew-Kleszczyński,Tomasz, AU - Umiński,Jacek, AU - Zubilewicz,Tomasz, AU - Kobusiewicz,Wojciech, AU - Iłżecki,Marek, AU - Wojtak,Andrzej, AU - Stec,Janusz, AU - Urbanek,Tomasz, Y1 - 2015/09/25/ PY - 2015/9/26/entrez PY - 2015/9/26/pubmed PY - 2016/12/15/medline SP - 98 EP - 107 JF - International angiology : a journal of the International Union of Angiology JO - Int Angiol VL - 35 IS - 1 N2 - BACKGROUND: To assess patients' satisfaction from the therapy of advanced chronic venous disorders (CVD) in everyday clinical practice in Poland, and to compare the efficacy of various venoactive drugs (VADs) in venous ulcers healing process. METHODS: Seven hundred and eighty unselected adult patients with active (N.=441) or healed (N.=339) venous ulcers participated in the non-interventional observational 6-week study. RESULTS: Compression therapy and VADs were utilized by 81.5% and 89.2% of patients respectively: 31.2% of all patients underwent surgical procedures for vein incompetence, 61.3% were satisfied with surgical methods, 43% with compression therapy, and 32.6% with VADs ‑ with highest rate of satisfied patients in the group taking Ruscus aculeatus and HMC and ascorbic acid (51.4%). Of 377 patients with active venous ulcers smaller than 200 cm2, adherent to VADs, 18.0% have been cured, and 66.6% have improved during 6-week period of observation. Multiple logistic regression analysis revealed that the compression therapy (OR=2.74), the size of ulcer ≤10 cm2 (OR=2.70) were increasing the change of ulcer healing. No VADs was better than another in the healing process. CONCLUSION: 1) Compression therapy and VADs are highly utilized by patients with advanced CVD. 2) Patients are more satisfied with surgical than conservative treatment of advanced CVD. 3) More than half of the patients with the advanced stage CVD taking Ruscus aculeatus and HMC and ascorbic acid is satisfied with the obtained improvement. 4) Ruscus aculeatus and HMC and ascorbic acid is similarly effective as other frequently used VADs in venous ulcer healing. 5) Ruscus aculeatus and HMC and ascorbic acid exerting effects on veins, capillaries and lymphatic vessels may explain the positive results observed in this study. SN - 1827-1839 UR - https://www.unboundmedicine.com/medline/citation/26406967/Patients'_satisfaction_with_therapy_methods_of_advanced_chronic_venous_disease_ DB - PRIME DP - Unbound Medicine ER -