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Clinical Presentation of Chiari I Malformation and Syringomyelia in Children.
Neurosurg Clin N Am. 2015 Oct; 26(4):509-14.NC

Abstract

Chiari I malformation and syringomyelia may be associated with a wide spectrum of symptoms and signs in children. Clinical presentations vary based on patient age and relative frequency; some diagnoses represent incidental radiographic findings. Occipitocervical pain, propagated or intensified by Valsalva maneuvers (or generalized irritability in younger patients unable to communicate verbally), and syringomyelia with or without scoliosis are the most common clinical presentations. Cranial nerve or brainstem dysfunction also may be observed in younger patients, and is associated with more complex deformity that includes ventral compression secondary to basilar invagination, retroflexion of the dens, and/or craniocervical instability.

Authors+Show Affiliations

Division of Pediatric Neurosurgery, Department of Neurosurgery, Children's of Alabama, University of Alabama, Birmingham (UAB), 1600 7th Avenue South, Lowder 400, Birmingham, AL 35233, USA.Division of Pediatric Neurosurgery, Department of Neurosurgery, Children's of Alabama, University of Alabama, Birmingham (UAB), 1600 7th Avenue South, Lowder 400, Birmingham, AL 35233, USA. Electronic address: James.Johnston@childrensal.org.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

26408059

Citation

Pindrik, Jonathan, and James M. Johnston. "Clinical Presentation of Chiari I Malformation and Syringomyelia in Children." Neurosurgery Clinics of North America, vol. 26, no. 4, 2015, pp. 509-14.
Pindrik J, Johnston JM. Clinical Presentation of Chiari I Malformation and Syringomyelia in Children. Neurosurg Clin N Am. 2015;26(4):509-14.
Pindrik, J., & Johnston, J. M. (2015). Clinical Presentation of Chiari I Malformation and Syringomyelia in Children. Neurosurgery Clinics of North America, 26(4), 509-14. https://doi.org/10.1016/j.nec.2015.06.004
Pindrik J, Johnston JM. Clinical Presentation of Chiari I Malformation and Syringomyelia in Children. Neurosurg Clin N Am. 2015;26(4):509-14. PubMed PMID: 26408059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical Presentation of Chiari I Malformation and Syringomyelia in Children. AU - Pindrik,Jonathan, AU - Johnston,James M,Jr Y1 - 2015/08/04/ PY - 2015/9/27/entrez PY - 2015/9/27/pubmed PY - 2016/8/26/medline KW - Cervicomedullary junction KW - Chiari I malformation KW - Craniocervical junction KW - Headache KW - Scoliosis KW - Syringomyelia KW - Syrinx SP - 509 EP - 14 JF - Neurosurgery clinics of North America JO - Neurosurg Clin N Am VL - 26 IS - 4 N2 - Chiari I malformation and syringomyelia may be associated with a wide spectrum of symptoms and signs in children. Clinical presentations vary based on patient age and relative frequency; some diagnoses represent incidental radiographic findings. Occipitocervical pain, propagated or intensified by Valsalva maneuvers (or generalized irritability in younger patients unable to communicate verbally), and syringomyelia with or without scoliosis are the most common clinical presentations. Cranial nerve or brainstem dysfunction also may be observed in younger patients, and is associated with more complex deformity that includes ventral compression secondary to basilar invagination, retroflexion of the dens, and/or craniocervical instability. SN - 1558-1349 UR - https://www.unboundmedicine.com/medline/citation/26408059/Clinical_Presentation_of_Chiari_I_Malformation_and_Syringomyelia_in_Children_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1042-3680(15)00045-5 DB - PRIME DP - Unbound Medicine ER -