Tags

Type your tag names separated by a space and hit enter

Spinal Deformity Associated with Chiari Malformation.
Neurosurg Clin N Am. 2015 Oct; 26(4):579-85.NC

Abstract

Despite the frequency of Chiari-associated spinal deformities, this disease process remains poorly understood. Syringomyelia is often present; however, this is not necessary and scoliosis has been described in the absence of a syrinx. Decompression of the hindbrain is often recommended. In young patients (<10 years old) and/or those with small coronal Cobb measurements (<40°), decompression of the hindbrain may lead to resolution of the spinal deformity. Spinal fusion is reserved for those curves that progress to deformities greater than 50°. Further research is needed to understand the underlying pathophysiology to improve prognostication and treatment of this patient population.

Authors+Show Affiliations

Department of Orthopedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Box 8233, Saint Louis, MO 63110, USA. Electronic address: kellymi@wudosis.wustl.edu.Department of Orthopedic Surgery, Gillette Children's Hospital, 200 University Ave E, St Paul, MN 55101, USA.Department of Orthopedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Box 8233, Saint Louis, MO 63110, USA.

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Review

Language

eng

PubMed ID

26408068

Citation

Kelly, Michael P., et al. "Spinal Deformity Associated With Chiari Malformation." Neurosurgery Clinics of North America, vol. 26, no. 4, 2015, pp. 579-85.
Kelly MP, Guillaume TJ, Lenke LG. Spinal Deformity Associated with Chiari Malformation. Neurosurg Clin N Am. 2015;26(4):579-85.
Kelly, M. P., Guillaume, T. J., & Lenke, L. G. (2015). Spinal Deformity Associated with Chiari Malformation. Neurosurgery Clinics of North America, 26(4), 579-85. https://doi.org/10.1016/j.nec.2015.06.005
Kelly MP, Guillaume TJ, Lenke LG. Spinal Deformity Associated With Chiari Malformation. Neurosurg Clin N Am. 2015;26(4):579-85. PubMed PMID: 26408068.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spinal Deformity Associated with Chiari Malformation. AU - Kelly,Michael P, AU - Guillaume,Tenner J, AU - Lenke,Lawrence G, Y1 - 2015/08/04/ PY - 2015/9/27/entrez PY - 2015/9/27/pubmed PY - 2016/8/26/medline KW - Chiari malformation KW - Early onset KW - Scoliosis KW - Syringomyelia KW - Syrinx SP - 579 EP - 85 JF - Neurosurgery clinics of North America JO - Neurosurg Clin N Am VL - 26 IS - 4 N2 - Despite the frequency of Chiari-associated spinal deformities, this disease process remains poorly understood. Syringomyelia is often present; however, this is not necessary and scoliosis has been described in the absence of a syrinx. Decompression of the hindbrain is often recommended. In young patients (<10 years old) and/or those with small coronal Cobb measurements (<40°), decompression of the hindbrain may lead to resolution of the spinal deformity. Spinal fusion is reserved for those curves that progress to deformities greater than 50°. Further research is needed to understand the underlying pathophysiology to improve prognostication and treatment of this patient population. SN - 1558-1349 UR - https://www.unboundmedicine.com/medline/citation/26408068/Spinal_Deformity_Associated_with_Chiari_Malformation_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1042-3680(15)00046-7 DB - PRIME DP - Unbound Medicine ER -