Tags

Type your tag names separated by a space and hit enter

Comparison of the Anti-Adhesion Activity of Three Different Cranberry Extracts on Uropathogenic P-fimbriated Escherichia coli: a Randomized, Double-blind, Placebo Controlled, Ex Vivo, Acute Study.
Nat Prod Commun 2015; 10(7):1215-8NP

Abstract

Research suggests that cranberry (Vaccinium macrocarpon) helps maintain urinary tract health. Bacterial adhesion to the uroepithelium is the initial step in the progression to development of a urinary tract infection. The bacterial anti-adhesion activity of cranberry proanthocyanidins (PACs) has been demonstrated in vitro. Three different cranberry extracts were developed containing a standardized level of 36 mg of PACs. This randomized, double-blind, placebo controlled, ex vivo, acute study was designed to compare the anti-adhesion activity exhibited by human urine following consumption of three different cranberry extracts on uropathogenic P-fimbriated Escherichia coli in healthy men and women. All three cranberry extracts significantly increased anti-adhesion activity in urine. from 6 to 12 hours after intake of a single dose standardized to deliver 36 mg of PACs (as measured by the BL-DMAC method), versus placebo.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26411014

Citation

Howell, Amy, et al. "Comparison of the Anti-Adhesion Activity of Three Different Cranberry Extracts On Uropathogenic P-fimbriated Escherichia Coli: a Randomized, Double-blind, Placebo Controlled, Ex Vivo, Acute Study." Natural Product Communications, vol. 10, no. 7, 2015, pp. 1215-8.
Howell A, Souza D, Roller M, et al. Comparison of the Anti-Adhesion Activity of Three Different Cranberry Extracts on Uropathogenic P-fimbriated Escherichia coli: a Randomized, Double-blind, Placebo Controlled, Ex Vivo, Acute Study. Nat Prod Commun. 2015;10(7):1215-8.
Howell, A., Souza, D., Roller, M., & Fromentin, E. (2015). Comparison of the Anti-Adhesion Activity of Three Different Cranberry Extracts on Uropathogenic P-fimbriated Escherichia coli: a Randomized, Double-blind, Placebo Controlled, Ex Vivo, Acute Study. Natural Product Communications, 10(7), pp. 1215-8.
Howell A, et al. Comparison of the Anti-Adhesion Activity of Three Different Cranberry Extracts On Uropathogenic P-fimbriated Escherichia Coli: a Randomized, Double-blind, Placebo Controlled, Ex Vivo, Acute Study. Nat Prod Commun. 2015;10(7):1215-8. PubMed PMID: 26411014.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of the Anti-Adhesion Activity of Three Different Cranberry Extracts on Uropathogenic P-fimbriated Escherichia coli: a Randomized, Double-blind, Placebo Controlled, Ex Vivo, Acute Study. AU - Howell,Amy, AU - Souza,Dan, AU - Roller,Marc, AU - Fromentin,Emilie, PY - 2015/9/29/entrez PY - 2015/9/29/pubmed PY - 2015/11/17/medline SP - 1215 EP - 8 JF - Natural product communications JO - Nat Prod Commun VL - 10 IS - 7 N2 - Research suggests that cranberry (Vaccinium macrocarpon) helps maintain urinary tract health. Bacterial adhesion to the uroepithelium is the initial step in the progression to development of a urinary tract infection. The bacterial anti-adhesion activity of cranberry proanthocyanidins (PACs) has been demonstrated in vitro. Three different cranberry extracts were developed containing a standardized level of 36 mg of PACs. This randomized, double-blind, placebo controlled, ex vivo, acute study was designed to compare the anti-adhesion activity exhibited by human urine following consumption of three different cranberry extracts on uropathogenic P-fimbriated Escherichia coli in healthy men and women. All three cranberry extracts significantly increased anti-adhesion activity in urine. from 6 to 12 hours after intake of a single dose standardized to deliver 36 mg of PACs (as measured by the BL-DMAC method), versus placebo. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/26411014/Comparison_of_the_Anti_Adhesion_Activity_of_Three_Different_Cranberry_Extracts_on_Uropathogenic_P_fimbriated_Escherichia_coli:_a_Randomized_Double_blind_Placebo_Controlled_Ex_Vivo_Acute_Study_ L2 - https://medlineplus.gov/urinarytractinfections.html DB - PRIME DP - Unbound Medicine ER -