TY - JOUR T1 - Nickel/cobalt oxide-decorated 3D graphene nanocomposite electrode for enhanced electrochemical detection of urea. AU - Nguyen,Nhi Sa, AU - Das,Gautam, AU - Yoon,Hyon Hee, Y1 - 2015/09/25/ PY - 2015/06/19/received PY - 2015/09/06/revised PY - 2015/09/21/accepted PY - 2015/10/4/entrez PY - 2015/10/4/pubmed PY - 2016/9/13/medline KW - 3D graphene KW - Ni–Co oxide KW - Non-enzymatic KW - Urea sensor KW - Urine SP - 372 EP - 7 JF - Biosensors & bioelectronics JO - Biosens Bioelectron VL - 77 N2 - A NiCo2O4 bimetallic electro-catalyst was synthesized on three-dimensional graphene (3D graphene) for the non-enzymatic detection of urea. The structural and morphological properties of the NiCo2O4/3D graphene nanocomposite were characterized by X-ray diffraction, Raman spectroscopy, and scanning electron microscopy. The NiCo2O4/3D graphene was deposited on an indium tin oxide (ITO) glass to fabricate a highly sensitive urea sensor. The electrochemical properties of the prepared electrode were studied by cyclic voltammetry. A high sensitivity of 166 μAmM(-)(1)cm(-)(2) was obtained for the NiCo2O4/3D graphene/ITO sensor. The sensor exhibited a linear range of 0.06-0.30 mM (R(2)=0.998) and a fast response time of approximately 1.0 s with a detection limit of 5.0 µM. Additionally, the sensor exhibited high stability with a sensitivity decrease of only 5.5% after four months of storage in ambient conditions. The urea sensor demonstrates feasibility for urea analysis in urine samples. SN - 1873-4235 UR - https://www.unboundmedicine.com/medline/citation/26433071/Nickel/cobalt_oxide_decorated_3D_graphene_nanocomposite_electrode_for_enhanced_electrochemical_detection_of_urea_ DB - PRIME DP - Unbound Medicine ER -