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Low rate of advanced adenoma formation during a 5-year colonoscopy surveillance period after adequate polypectomy of non-advanced adenoma.
Colorectal Dis. 2016 Feb; 18(2):179-86.CD

Abstract

AIM

Patients with non-advanced adenoma (NAA) underwent surveillance colonoscopy at intervals shorter than the interval recommended by the guidelines. We aimed to assess the incidence of recurrent advanced adenoma (AA) over a 5-year period and to identify risk factors for recurrence.

METHOD

Patients with and without NAA identified at baseline colonoscopy who had had at least two colonoscopy examinations during the subsequent 5 years were included in the study. Data on the patients' demographics and colorectal findings were extracted from a specially designed colonoscopy database. The primary outcome was the finding of recurrent AA formation. Multivariate analysis was used to identify factors that predict subsequent AA formation at surveillance colonoscopy.

RESULTS

Among 43 155 colonoscopy procedures, 828 cases were identified with NAA (374) and without an adenoma (454). Forty-eight (51.1%) of 94 received a follow-up colonoscopy within 1 year due to an inadequate baseline colonoscopy. Patients with NAA at baseline had a low incidence of AA at an interval of 1-5 years which was not statistically different from patients without adenoma formation at the initial baseline colonoscopy (1.5% vs 2.2%, P = 0.51). The incidence of AA at follow-up colonoscopy performed at 1-3 years and 3-5 years in patients with a baseline NAA was 1.7% and 1.4% (P = 0.59). Age over 50 years and male gender were independent risk factors for AA recurrence within 5 years.

CONCLUSION

Surveillance colonoscopy within 5 years is of little benefit to patients who had an adequate polypectomy of an NAA at baseline. Too frequent reexamination due to concerns about AA recurrence should be avoided.

Authors+Show Affiliations

Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China. Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, Tianjin, China.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

26456236

Citation

Xu, M, et al. "Low Rate of Advanced Adenoma Formation During a 5-year Colonoscopy Surveillance Period After Adequate Polypectomy of Non-advanced Adenoma." Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland, vol. 18, no. 2, 2016, pp. 179-86.
Xu M, Wang S, Cao H, et al. Low rate of advanced adenoma formation during a 5-year colonoscopy surveillance period after adequate polypectomy of non-advanced adenoma. Colorectal Dis. 2016;18(2):179-86.
Xu, M., Wang, S., Cao, H., Wang, W., Piao, M., Cao, X., Yan, F., & Wang, B. (2016). Low rate of advanced adenoma formation during a 5-year colonoscopy surveillance period after adequate polypectomy of non-advanced adenoma. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland, 18(2), 179-86. https://doi.org/10.1111/codi.13148
Xu M, et al. Low Rate of Advanced Adenoma Formation During a 5-year Colonoscopy Surveillance Period After Adequate Polypectomy of Non-advanced Adenoma. Colorectal Dis. 2016;18(2):179-86. PubMed PMID: 26456236.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Low rate of advanced adenoma formation during a 5-year colonoscopy surveillance period after adequate polypectomy of non-advanced adenoma. AU - Xu,M, AU - Wang,S, AU - Cao,H, AU - Wang,W, AU - Piao,M, AU - Cao,X, AU - Yan,F, AU - Wang,B, PY - 2015/03/14/received PY - 2015/05/27/accepted PY - 2015/10/13/entrez PY - 2015/10/13/pubmed PY - 2016/10/22/medline KW - Colorectal adenoma KW - colonoscopy KW - polypectomy KW - surveillance SP - 179 EP - 86 JF - Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland JO - Colorectal Dis VL - 18 IS - 2 N2 - AIM: Patients with non-advanced adenoma (NAA) underwent surveillance colonoscopy at intervals shorter than the interval recommended by the guidelines. We aimed to assess the incidence of recurrent advanced adenoma (AA) over a 5-year period and to identify risk factors for recurrence. METHOD: Patients with and without NAA identified at baseline colonoscopy who had had at least two colonoscopy examinations during the subsequent 5 years were included in the study. Data on the patients' demographics and colorectal findings were extracted from a specially designed colonoscopy database. The primary outcome was the finding of recurrent AA formation. Multivariate analysis was used to identify factors that predict subsequent AA formation at surveillance colonoscopy. RESULTS: Among 43 155 colonoscopy procedures, 828 cases were identified with NAA (374) and without an adenoma (454). Forty-eight (51.1%) of 94 received a follow-up colonoscopy within 1 year due to an inadequate baseline colonoscopy. Patients with NAA at baseline had a low incidence of AA at an interval of 1-5 years which was not statistically different from patients without adenoma formation at the initial baseline colonoscopy (1.5% vs 2.2%, P = 0.51). The incidence of AA at follow-up colonoscopy performed at 1-3 years and 3-5 years in patients with a baseline NAA was 1.7% and 1.4% (P = 0.59). Age over 50 years and male gender were independent risk factors for AA recurrence within 5 years. CONCLUSION: Surveillance colonoscopy within 5 years is of little benefit to patients who had an adequate polypectomy of an NAA at baseline. Too frequent reexamination due to concerns about AA recurrence should be avoided. SN - 1463-1318 UR - https://www.unboundmedicine.com/medline/citation/26456236/Low_rate_of_advanced_adenoma_formation_during_a_5_year_colonoscopy_surveillance_period_after_adequate_polypectomy_of_non_advanced_adenoma_ L2 - https://doi.org/10.1111/codi.13148 DB - PRIME DP - Unbound Medicine ER -